Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care

2262 Camino Ramon, San Ramon, CA 94583
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

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MEDICAL DERMATOLOGY

Acne and Acne Scar

Excimer Laser for Psoriasis & Vitiligo

Keloid & Hypertrophic Scar Laser Therapy

Mohs Surgery for Skin Cancers

Nail Fungus GenesisPlus Laser Therapy

Photodynamic Therapy

Psoriasis & NBUVB Phototherapy

RadioTherapy Nonsurgical SRT-100 for Skin Cancer

Skin Allergy Patch Test

Sweating Disorder MiraDry for Hyperhidrosis

Wart Laser Therapy


COSMETIC DERMATOLOGY

Aesthetician Services
Microdermabrasion
 

Botox, Dysport & Xeomin

Cellulaze Cellulite Therapy

new! CoolSculpting

Facial Redness/Vein Laser Therapy

Fillers injection for Wrinkles

Fractional CO2 laser

new! Hair Transplant with Neograft

Laser Surgery Services
Acne/Pore reducing Laser
Collagen Stimulating Laser
Excimer Laser
Facial Veins laser
Hair Laser Removal
IPL Fotofacial
Melasma Laser
Nail Fungus Laser
Resurfacing Laser
Scar revision Laser
Tattoo Removal Lasers
VBeam Pulse Dye Laser
Wart Laser


Latisse

Leg Vein Laser Therapy & Asclera Sclerotherapy

Liposonix + Vaser Shape Nonsurgical Body Sculpting
 

Melasma and Pigmentation

Pore Size Reduction and Laser Rejuvenation

Sculptra Liquid Facelift

SideLaze Lift

Ulthera natural lift & skin tightening of face and neck


Related Websites
FaceUpLifting.com
iCellulaze.com
MoreHair4Me.com
SideLazeLift.com
SonixLipo.com


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Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Wed, 17 Dec 2014 04:25:26 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Dec 16, 2014 08:24PM

Angioimmunoblastic T-Cell Lymphoma: A Diagnostic Challenge

We present the illustrative case of a 55-year-old woman with an AITL who presented prominent skin findings, arthritis, lymphadenopathy and hypereosinophilia. Skin biopsy reported a T-cell lymphoma and the diagnosis of AITL was confirmed by an axillary lymph node biopsy, which was also positive for Epstein-Barr virus. Chemotherapy with CHOP-21 and thalidomide was given, accomplishing complete remission after six cycles.Case Rep Dermatol 2014;6:291-295 (Source: Case Reports in Dermatology)

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Dec 16, 2014 08:24PM

Childhood actinic lichen planus: four cases report in Caucasian Spanish children and review of the literature

(Source: Journal of the European Academy of Dermatology and Venereology)

Dec 16, 2014 08:23PM

Your Wound Care Department Checklist for 2015

No abstract available (Source: Advances in Skin and Wound Care)

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Dec 16, 2014 08:23PM

The Incidence of Lower-Extremity Amputation and Bone Resection in Diabetic Foot Ulcer Patients Treated with a Human Fibroblast-Derived Dermal Substitute

CONCLUSION:There were significantly fewer amputations/bone resections in patients who received human fibroblast-derived dermal substitute versus conventional care, likely related to the lower incidence of infection adverse events observed in the human fibroblast-derived dermal substitute treatment group. (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

Antimicrobial-Impregnated Dressing Combined with Negative-Pressure Wound Therapy Increases Split-Thickness Skin Graft Engraftment: A Simple Effective Technique

CONCLUSION:Use of an AMD dressing with NPWT after split-thickness skin grafting can be an effective method to ensure good graft to wound contact and enhances skin graft take in chronic and contaminated wounds. (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

Pilot Study Compares Scores of the Resident Assessment Instrument Minimum Data Set Version 2.0 (MDS 2.0) Pressure Ulcer Risk Scale with the Braden Pressure Ulcer Risk Assessment for Patients in Complex Continuing Care

CONCLUSION:This preliminary study may provide some evidence that the MDS 2.0 PURS may be an alternative risk assessment tool option that utilizes mandatory collected data, reduces workload duplication, and would generate a Resident Assessment Protocol, when indicated, in complex continuing care. (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

Educational Opportunities, Expert Faculty, and Vendor Exhibits Seen at the Mirage

No abstract available (Source: Advances in Skin and Wound Care)

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Dec 16, 2014 08:23PM

Infrared Skin Thermometry: An Underutilized Cost-effective Tool for Routine Wound Care Practice and Patient High-Risk Diabetic Foot Self-monitoring

PURPOSE:To provide information about the use of infrared skin thermometry for routine wound care practice and patient high-risk diabetic foot self-monitoring. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant will be able to:1. Describe infrared thermometer use and the authors? study findings.2. Summarize studies that have evaluated the use of infrared thermometers for measuring skin temperature of the diabetic foot. ABSTRACTThe aim of this article is to provide practitioners with an overview of infrared skin thermometry for everyday wound care practice. Thermometers have the potential for home use by patients with neuropathy to self...

Dec 16, 2014 08:23PM

JoAnn R. Maklebust, DNP, MSN, RN, ACNS-BC, AOCN, FAAN (1934?2014)

No abstract available (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

Matching Editorial Content to the Educational Needs of Wound Care Professionals

No abstract available (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

2015: ?Key Word? for Wound Care Business Success

No abstract available (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:23PM

Validation of Commercially Available Infrared Thermometers for Measuring Skin Surface Temperature Associated with Deep and Surrounding Wound Infection

CONCLUSIONS:The results of this study demonstrate that less expensive, industrial-grade noncontact infrared thermometers have reliable temperature readings to identify and quantify the temperature gradients that along with other signs may be associated with deep and surrounding wound infection or tissue injury due to repeated microtrauma. (Source: Advances in Skin and Wound Care)

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Dec 16, 2014 08:23PM

Providing a Roadmap to Predict Tissue Viability

No abstract available (Source: Advances in Skin and Wound Care)

Dec 16, 2014 08:22PM

Long-Lasting Responses under Treatment with Ipilimumab: An Argument against Maintenance Therapy

We present three patients with metastatic melanoma who received ipilimumab after progression under chemotherapy. In all of these patients ipilimumab led to a long-term tumor control of at least 32 months. Interestingly, all of them developed severe autoimmune toxicity and ipilimumab treatment was discontinued after 1 respectively 2 cycles. The present cases demonstrate that a long-term response to ipilimumab can be achieved without maintenance therapy.Dermatology (Source: Dermatology)

Dec 16, 2014 04:00PM

The Influence of Age and Gender in Knowledge, Behaviors and Attitudes Towards Sun Protection: A Cross-Sectional Survey of Australian Outpatient Clinic Attendees

Conclusion This study highlights a number of gender- and age-specific findings with regards to sun protection. There are knowledge, attitude, and behavior deficiencies within each demographic group that need to be specifically targeted through educational and public health efforts in order to improve general sun protection measures and decrease the incidence of skin cancers. (Source: American Journal of Clinical Dermatology)

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Dec 16, 2014 02:22PM

Evaluating the impact of FDA?s pregnancy and lactation labeling rule

Since 1979, obstetric and other health care providers who treat pregnant or potentially pregnant and breastfeeding women have relied heavily on the Food and Drug Administration?s pregnancy labeling categories for pharmaceuticals ? the familiar A, B, C, D, X. However, as early as 1997, a public... (Source: Skin and Allergy News)

Dec 16, 2014 02:22AM

Recent Advances in Acne PathogenesisRecent Advances in Acne Pathogenesis

Learn how emerging acne treatment options can help improve patient outcomes. American Journal of Clinical Dermatology (Source: Medscape Today Headlines)

Dec 16, 2014 01:11AM

Exclusive: Service hit by staff 'exodus' after CCG transfers contract to Circle

One of the biggest teaching trusts in England has been forced to axe its once renowned acute dermatology service due to an ?exodus? of medical consultants following the transfer of their contract to private provider Circle. (Source: HSJ)

Dec 15, 2014 11:58PM

Paraneoplastic Syndrome: A Masquerade of Autoimmune Inner Ear Disease

We present three recent cases: one patient with a history of B-cell follicular lymphoma who developed dermatomyositis and hearing loss before detection of lymphoma recurrence in his anterior chest wall, a second patient with sudden asymmetric hearing loss, found to have a 12-cm renal mass before death, and a third with fluctuating bilateral hearing loss who was ultimately found to have a thymoma. Although characterized as type VI (non-immune rapidly progressive sensorineural hearing loss) within the Harris autoimmune inner ear disease classification system, the mechanism of paraneoplastic cochleovestibulopathy is not well understood. Although specific anti-neuronal antibodies such as anti-Hu may be associated with other paraneoplastic neurologic disorders, these antibodies have limited dia...

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Dec 15, 2014 10:18PM

Rapid Partial Repigmentation of Vitiligo in a Young Female Adult with a Gluten-Free Diet

Vitiligo is a common pigmentary skin condition with a profound impact. Despite a number of therapeutic modalities, few have been demonstrated to result in significant repigmentation within a brief period of time. Reported dietary interventions are sparse. Following exclusion of gluten in the diet, early and extensive repigmentation of facial lesions were noted in a young female adult of Asian ethnicity with acrofacial vitiligo. The majority of the benefits occurred within the first month and stabilized at 4 months. Previous topical and phototherapy had not been found to be effective. The patient was maintained on the previously prescribed dapsone therapy. Dietary elimination can potentially be a disease-modifying intervention for vitiligo and should be considered even in patients without c...

Dec 15, 2014 10:18PM

Calcinosis Cutis Long after Rhinoplasty with Silicone

Rhinoplasty is a plastic surgery procedure to reconstruct the nose. Silicone alloplastic materials are most widely used as implants for rhinoplasty, but calcification on the surface occurs with long-term usage. Herein, we report a case of gruel-like calcification approximately 50 years after silicone implant rhinoplasty. In this case, calcification on the silicone surface might have transformed into gruel-like deposits, which presented as a subcutaneous mass at the dorsal area of the nose. The precise mechanism is unclear; a pH change in the tissue might have occurred during the process of inflammation, leading to the dissolution of calcified deposits.Case Rep Dermatol 2014;6:288-290 (Source: Case Reports in Dermatology)

Dec 15, 2014 10:14PM

The Influence of the Acyl Chain on the Transdermal Penetration-Enhancing Effect of Synthetic Phytoceramides

Conclusion: The investigated PCERs exhibited a penetration-enhancing effect on caffeine and testosterone but not on ibuprofen.Skin Pharmacol Physiol 2015;28:124-136 (Source: Skin Pharmacology and Physiology)

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Dec 15, 2014 05:20PM

The study of cellular cytotoxicity of argireline - an anti-aging peptide.

In conclusion, the considered method resulted in dose-dependent argireline anti-proliferation effects. However, the significant cytotoxicity of argireline solution was observed under 18 to 10 000 fold higher concentrations (depending on cells that were examined) in comparison to doxorubicin. PMID: 24644551 [PubMed - indexed for MEDLINE] (Source: Acta Biochim Pol)

Dec 15, 2014 04:19PM

?Kaiser Permanente Hawaii launches virtual dermatology service

Kaiser Permanente Hawaii has launched teledermatology, a digital service that connects patients to their dermatologists to make the diagnosis process more efficient. Using a secure email server, patients can send their dermatologists photos of any suspicious moles, lesions and rashes via Kaiser Permanente HealthConnect, the electronic medical record system. The new process allows doctors to determine which patients need an in-person visit to their office, says Dr. Theresa Devere, chief of dermatology? (Source: bizjournals.com Health Care:Hospitals headlines)

Dec 15, 2014 04:00PM

Hospitalizations associated with influenza and respiratory syncytial virus among patients attending a network of private hospitals in South Africa, 2007¿2012

Background: Influenza and respiratory syncytial virus (RSV) infection are common causes of lower respiratory tract illness. Data on their burden in low and middle-income settings and from Africa are scarce. We aimed to estimate age-specific rates of hospitalization attributable to influenza and RSV among patients attending private hospitals in South Africa during 2007?2012. Methods: We estimated annual age-specific rates of influenza- and RSV-associated hospitalization (that is respiratory hospitalizations likely due to influenza or RSV infection) by applying regression models to monthly administrative hospitalization data from a national private hospital group, using influenza and RSV surveillance data as covariates. Results: Estimated mean hospitalization rates associated with seasonal i...

Dec 15, 2014 04:00PM

Neurofibromatosis Type 1 Diagnosed in a Child Based on Multiple Juvenile Xanthogranulomas and Juvenile Myelomonocytic Leukemia

Abstract An association between juvenile xanthogranuloma (JXG), neurofibromatosis type 1 (NF1), and juvenile myelomonocytic leukemia (JMML) has been described in the literature but has only been documented in approximately 20 cases. We diagnosed a patient with NF1 at 25 months of age, before any cutaneous stigmata of this disease had appeared, because we decided to screen for the NF1 gene mutation because of his presentation with multiple JXGs and moderate macrocephaly (2.5 standard deviations) at 9 months of age and JMML diagnosed at 20 months of age. The child is well today after treatment with chemotherapy and allogenic bone marrow transplantation. With increased awareness, patients with JXG and NF1 who develop symptoms possibly related to JMML, such as paleness, skin bleeding, cough...

Dec 15, 2014 04:00PM

Large Multifocal Cutaneous Hemangioma Along Lines of Blaschko with Cardiac Failure Treated with Propranolol

We report here the case of a large multifocal hemangioma along the lines of Blaschko with high?output cardiac failure, with improvement in cutaneous and hemodynamic symptoms after propranolol therapy. Presentation along the lines of Blaschko raises the possibility of hemangiomas arising as a result of mosaicism. (Source: Pediatric Dermatology)

Dec 15, 2014 04:00PM

Clinicopathologic Evaluation of Cardiofaciocutaneous Syndrome: Overcoming the Challenges of Diagnosing a Rare Genodermatosis

We report the case of a 2?year?old boy from a family with limited financial resources who presented with cutaneous abnormalities, a history of congenital heart defect, and a presumptive diagnosis of Noonan syndrome. Genetic testing had been deferred because of a lack of funds. Skin findings were characteristic of cardiofaciocutaneous syndrome, including keratosis pilaris, ichthyosis, sparse eyebrows, and multiple nevi. A biopsy of a perifollicular thick papule with background hyperpigmentation was obtained to further characterize the cutaneous findings. Clinical evaluation allowed rapid, cost?effective, specific diagnosis in this patient with a RASopathy?spectrum genetic disorder who did not have access to genetic testing. This time?honored clinical approach is adequate for provi...

Dec 15, 2014 04:00PM

Congenital Melanotic Macules of the Tongue. A Case Report and Brief Review of the Literature

We report the case of an African infant with multiple congenital hyperpigmented macules of the tongue. To avoid a difficult?to?perform procedure such as a tongue biopsy, focused clinical monitoring was performed every 3 months for 30 months to detect significant changes. A clinical diagnosis of CMMT was made in the absence of concomitant systemic diseases using the clinical findings, the location on the tongue, the negative family history for melanoma, and the absence of drugs and toxic exposure. Clinical follow?up may be sufficient to monitor CMMT rather than performing a tongue biopsy. (Source: Pediatric Dermatology)

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Dec 15, 2014 04:00PM

Early?Onset Heart Failure, Alopecia, and Cutaneous Abnormalities Associated with a Novel Compound Heterozygous Mutation in Desmoplakin

We report the case of a 3?year?old boy presenting with severe left?sided heart failure with a preceding history of cutaneous abnormalities including congenital alopecia, PPK, nail dystrophy, and follicular hyperkeratosis on the extensor surfaces. Genetic testing revealed a novel combination of two heterozygous mutations in the DSP gene encoding desmoplakin: R1400X and R2284X. Both are predicted to be deleterious to protein function. This case adds to our understanding of the spectrum of clinical presentations of syndromes associated with desmoplakin mutations and highlights the need for cardiac examination in patients with characteristic cutaneous findings. (Source: Pediatric Dermatology)

Dec 15, 2014 04:00PM

Case of Merkel cell carcinoma with squamous cell carcinoma possibly arising in chronic radiodermatitis of the hand

We report a case of Merkel cell carcinoma (MCC) on the dorsal aspect of the right middle finger associated with multiple squamous cell carcinomas (SCC) possibly arising in chronic radiation dermatitis of the hand of an 80?year?old surgeon. In spite of resection of the primary lesion and right axillary lymph nodes, he died of the tumor 5 months after the first visit. Cutaneous and lymph node lesions of MCC were negative for Merkel cell polyoma virus (MCPyV) by immunostaining using monoclonal antibody (CM2B4) and anti?large T antigen of MCPyV polyclonal antibody, and real?time polymerase chain reaction. Several differences in clinicopathological findings have been found between MCPyV?positive cases and negative ones. Several authors have reported that MCPyV?negative cases have a...

Dec 15, 2014 04:00PM

Cerebriform connective tissue nevus of lumbar

Abstract Connective tissue nevi represents a kind of hamartoma, and coalescence of the lesions in a cerebriform mode in the lumbar region without Proteus syndrome is rarely seen. Here, we report a 26?year?old woman presenting with nodules and plaques in her left lumbar region of 26 years in duration. Histopathological examination and Masson?trichrome stain showed increased dermal collagen bundles in a haphazard array. The diagnosis of connective tissue nevi was made. This is the first case report on cerebriform connective tissue nevi without Proteus syndrome in the lumbar region. (Source: The Journal of Dermatology)

Dec 15, 2014 04:00PM

Successful treatment of oral itraconazole for infantile hemangiomas: A case series

We present six cases of infantile hemangiomas successfully treated with oral itraconazole approximately 5 mg/kg per day. In the first month, the red color of the lesions became a little lighter and the growth of the lesions was controlled in all cases. An obvious clinical improvement was noted in all cases during the 3?month period, with 80?100% improvement in each patient at the end of the treatment, which was judged by both their parents and the dermatologists. Compliance with treatment instructions of oral itraconazole in infants was judged to be very good. Side?effects were mild and limited. Although itraconazole can inhibit angiogenesis and tumor growth in vitro and in vivo associated with some cancers, further research is required to understand the pathogenesis of infantile he...

Dec 15, 2014 04:00PM

Human papillomavirus evaluation of vemurafenib?induced skin epithelial tumors: a case series

(Source: British Journal of Dermatology)

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Dec 15, 2014 04:00PM

A case of recurrent facial herpes simplex mimicking hydroa vacciniforme

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Language barriers: challenges to quality healthcare

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Generalized acquired cutis laxa with papular lesions

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Teledermatology: a possible reality in rural India

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Post?herpetic eosinophilic papules and plaques

(Source: International Journal of Dermatology)

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Dec 15, 2014 04:00PM

Psoriasis?associated IgA nephropathy under infliximab therapy

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

A giant lump on the shoulder

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

The Worst Itch Numeric Rating Scale for patients with moderate to severe plaque psoriasis or psoriatic arthritis

Abstract Plaque psoriasis (PP) and psoriatic arthritis (PsA) are autoinflammatory chronic conditions associated with skin involvement. Pruritus, or itching, is a prevalent and bothersome symptom in patients with PP and is associated with reduced health?related quality of life. The Worst Itch Numeric Rating Scale (WI?NRS) has been developed as a simple, single item with which to assess the patient?reported severity of this symptom at its most intense during the previous 24?hour period. Qualitative research was undertaken to assess the content validity of the WI?NRS. Patients with moderate to severe PP and patients with PsA were recruited from clinical sites in the USA. The qualitative research entailed two?part interviews, which began with concept elicitation to gain understandi...

Dec 15, 2014 04:00PM

Systematic review of treatments for chronic spontaneous urticaria with inadequate response to licensed first?line treatments

ConclusionsThis review confirms that available evidence to guide treatment choice for patients with CSU with inadequate response to H1 antihistamines varies in quality. Further research is warranted due to low?quality trials with methodological and reporting limitations. (Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Cylindroma: an update

Abstract This paper reviews the recent literature on cylindroma, a rare tumor originating from the cutaneous adnexal structures of the scalp and face. Benign cylindroma is more frequent in women, and there are solitary and multiple forms, which are autosomal. Malignant cylindroma can occur in the Brooke?Spiegler syndrome, and malignant transformation is more frequent in multiple variants than in solitary tumors. Its histopathological basis is controversial, and its origin is unknown, although it is known that there is a genetic basis for onset of these tumors in Brooke?Spiegler syndrome. (Source: International Journal of Dermatology)

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Dec 15, 2014 04:00PM

De rerum natura: a case of irritant phytodermatitis from Ranunculus bulbosus

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Total body photography for skin cancer screening

ConclusionsRapid?acquisition automated skin photography is feasible with a low?cost system, with excellent lesion visualization and participant acceptance. These data provide a basis for employing this method in clinical melanoma screening. (Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Eosinophilic annular erythema in a patient with metastatic prostate adenocarcinoma

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Periorbital indurated lesions in a 67?year?old female patient

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Panatrophy of Gowers is a rare disease: case reports and review of the literature

ConclusionsThis disorder is not as rare as it is assumed to be, probably because it is misdiagnosed as post?steroid atrophy; thus PG requires more attention. Seven patients with PG are reported here to counteract the supposed rarity of this disorder and to highlight findings of hypopigmentation mimicking steroid?induced atrophy. (Source: International Journal of Dermatology)

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Dec 15, 2014 04:00PM

Long pulsed 1064 nm Nd:YAG laser treatment for wrinkle reduction and skin laxity: evaluation of new parameters

ConclusionNew parameters of LPND can achieve wrinkle improvement with few side effects. (Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Expression of transforming growth factor?? after different non?invasive facial rejuvenation modalities

ConclusionsRadiofrequency, ELOS, and Nd:YAG 1320?nm laser and Er:YAG 2940?nm laser mini?peels resulted in an increase in TGF?? expression, which may mediate the effects of these modalities in enhancing dermal collagen expression through the activation of fibroblasts and thereby reverse the photoaging of skin. (Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Eccrine porocarcinoma: epidemiologic and histopathologic characteristics

ConclusionsOur series presents some clinical and histopathology differences with previously reported, such as the most frequent localization in the head and the presence of melanocyte colonization. (Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

The pathogenesis of herpes zoster duplex bilateralis symmetricus

(Source: International Journal of Dermatology)

Dec 15, 2014 04:00PM

Inadequate response to ustekinumab in atopic dermatitis ? a report of two patients

(Source: Journal of the European Academy of Dermatology and Venereology)

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Dec 15, 2014 04:00PM

Lymph node melanosis. Should it be managed as a high?risk melanoma? A case report and review of the literature

(Source: Journal of the European Academy of Dermatology and Venereology)

Dec 15, 2014 04:00PM

Mycobacterium marinum infection initially diagnosed as metastatic Crohn's disease

(Source: Journal of the European Academy of Dermatology and Venereology)

Dec 15, 2014 04:00PM

Comorbidity profiles in association with vitiligo: a nationwide population?based study in Taiwan

ConclusionOur study not only confirmed the significant association of vitiligo with multiple autoimmune and atopic diseases in Taiwan but also disclosed several unique findings, including the much lower prevalence of vitiligo, delayed onset of vitiligo by three decades, different associated comorbidity profiles comparing to westerners and the age? and gender?specific approach for the vitiligo?associated comorbidities. (Source: Journal of the European Academy of Dermatology and Venereology)

Dec 15, 2014 04:00PM

Acral peeling skin syndrome resulting from mutations in TGM5

(Source: Journal of the European Academy of Dermatology and Venereology)

Dec 15, 2014 04:00PM

Finger and toenail onycholysis

Abstract Onycholysis ? the separation of the nail plate from the nail bed occurs in fingers and toenails. It is diagnosed by the whitish appearance of the separated nail plate from the nail bed. In fingers, the majority is caused by trauma, manicuring, occupational or self?induced behavior. The most common disease producing fingernail onycholysis is psoriasis and pustular psoriasis. Phototoxic dermatitis, due to drugs can also produce finger onycholysis. Once the separation occurs, the environmental flora sets up temporary colonization in the available space. Finger onycholysis is most common in women. Candida albicans is often recovered from the onycholytic space. Many reports, want to associate the yeast as cause and effect, but the data are lacking and the treatment of the candida d...

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Dec 15, 2014 04:00PM

Verneuil's disease, innate immunity and vitamin D: a pilot study

ConclusionOur study shows that Verneuil's disease is associated with a major vitamin D deficiency, correlated with the disease severity. It suggests that vitamin D could significantly improve the inflammatory nodules, probably by stimulating the skin innate immunity. A larger randomized study is needed to confirm these findings. (Source: Journal of the European Academy of Dermatology and Venereology)

Dec 15, 2014 03:45PM

Lasers for nevi: a review

This article serves as a comprehensive review of available laser treatments for nevi and discusses the appropriate measures that should be taken before and after laser therapy. Based on the reviewed literature, laser treatment has generally been proven to be a safe and effective therapy for nevi with minimal side effects. (Source: Lasers in Medical Science)

Dec 15, 2014 02:00PM

Burns, fainting, eyes most common indoor tanning injuries

Skin burns, fainting, and eye injuries are the most common indoor tanning injuries requiring a trip to the local emergency department, according to a research letter published online Dec. 15 in JAMA Internal... (Source: Skin and Allergy News)

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Dec 15, 2014 01:28PM

Alpinia officinarum

(and its close relative Alpinia galanga), a member of the Zingiberaceae family (Zhong Xi Yi Jie He Xue Bao 2011;9:1061-5), has long been used in Chinese... (Source: Skin and Allergy News)

Dec 15, 2014 12:27PM

Rapid syphilis test cleared for use in medical offices, hospitals

A screening test for syphilis that can produce results in 12 minutes has been granted a waiver, allowing it ?to be used in a greater variety of health care settings,? including physician?s offices, the Food and Drug Administration announced on Dec. 15. The Syphilis Health Check test, which uses a...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

Dec 15, 2014 06:13AM

Maintenance tacrolimus for eczema boosts quality of life

AMSTERDAM ? Twice-weekly proactive maintenance therapy with 0.1% tacrolimus ointment in adults with moderate to severe atopic dermatitis resulted in dramatic improvement in self-reported quality of life in a 12-month observational study. This prospective study was designed to assess patients? own...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

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Dec 15, 2014 05:00AM

PODCAST: Congressional Fail on SGR, Medicaid pay parity

The 113th Congress ended with a bang, jamming almost a year?s worth of work into a single bill ? one that pretty much skipped over most of what was on physicians? priority list. The $1.1 trillion spending...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

Dec 14, 2014 04:57PM

Novartis Psoriasis Drug Tops J and J's StelaraNovartis Psoriasis Drug Tops J and J's Stelara

Novartis said on Friday its experimental psoriasis drug Cosentyx (secukinumab) was better at clearing the rough skin patches associated with the disease than Johnson & Johnson's Stelara (ustekinumab). Reuters Health Information (Source: Medscape Medical News Headlines)

Dec 14, 2014 04:19PM

What Are Risk Factors for Progression To Severe Disease with Bronchiolitis?

Discussion Bronchiolitis is a clinical disease with following features: begins usually with rhinitis and cough that may progress to also having tachypnea, rales, wheezing and increased work of breathing shown by nasal flaring and/or accessory muscle use. The increased work of breathing may cause problems with feeding and hydration and also with mental status changes. It is usually seen in infants and children < 2 years of age. It is also usually seasonal (winter in upper North America) with 60-70% of cases being caused by respiratory syncytial virus but also human rhinorvirus, human metapneumovirus, influenza, adenovirus, coronavirus and human and parainfluenza viruses. Co-infections also are relatively common. Diagnosis is clinical. Treatment includes secretion removal from the nose, ...

Dec 14, 2014 04:00PM

Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid-DPPC microparticles as a wound healing system

Publication date: Available online 12 December 2014 Source:Colloids and Surfaces B: Biointerfaces Author(s): ?pek Ero?lu , Evren H Gökçe , Nicolas Tsapis , Sakine Tuncay Tanr?verdi , Göksel Gökçe , Elias Fattal , Özgen Özer Resveratrol (RSV) was incorporated into microparticles by spray drying to treat chronic wounds such as diabetic ulcers. RSV was chosen due to its defense mechanisms as the formation of free radicals delays the healing process. RSV was loaded into microparticles consisting of dipalmitoylphosphatidylcholine (DPPC) and hyaluronic acid (HA), a polysaccharide naturally present within the skin, known to contribute to the healing process. Microparticles were evaluated in terms of production yield, size distribution, encapsulation efficiency, morphology, specific su...

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Dec 14, 2014 04:00PM

Demographic and clinical differences between unilateral and bilateral forms of nevoid telangiectasia: a retrospective study with review of literature

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Treatment of two patients with generalised pustular psoriasis with the interleukin?1? inhibitor gevokizumab

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

The Prevalence of Burning Mouth Syndrome: A Population?Based Study

ConclusionsTo our knowledge, we provide the first report of population?based BMS prevalence. The data show that BMS most commonly affects women older than 50 years, and when defined through diagnostic criteria, it is less prevalent than described previously.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Dec 14, 2014 04:00PM

Actual practice of melanoma follow?up and treatment in Germany: Results of a prospective, longitudinal cohort study

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Alpha?1?antitrypsin deficiency panniculitis presenting with severe anasarca, pulmonary embolus, and hypogammaglobulinemia

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Oral squamous cell carcinoma and hyperkeratotic lesions with BRAF inhibitors

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Cervical screening uptake in a dermatology cohort on immunosuppressive agents

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Mobile teledermatology for a prompter and more efficient dermatological care in rural Mongolia

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Dec 14, 2014 04:00PM

Th17 cytokines expression in leprosy skin lesions

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

A case of panniculitis caused by Mycobacterium massiliense mimicking erythema induratum

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Plasma concentrations of lignocaine and prilocaine and analgesic efficacy in leg ulcer?related pain during 10 days? daily application of lignocaine?prilocaine cream (EMLA?)

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Combination of ablative fractional laser and daylight?mediated photodynamic therapy for actinic keratosis in organ transplant recipients ? a randomized controlled trial

ConclusionsAFL?dPDT is a novel PDT modality that enhances CR with excellent tolerability compared with dPDT and cPDT in difficult?to?treat AK in OTR. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Ehlers-Danlos syndrome: how to diagnose and when to perform genetic tests

The term Ehlers–Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many subtypes has now been elucidated, confirming heterogeneity. An awareness of the different conditions within this group is the starting point towards accurate diagnosis. Accurate elicitation of history and clinical signs is vital in selecting the correct confirmatory investigation. Skin biopsy with electron microscopy can be helpful in the decision process of whether and when to perform genetic testing. Correct diagnosis within the EDSs allows targeted management, family s...

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Dec 14, 2014 04:00PM

The root cause of a blistering eruption

A 3-year-old girl was referred to paediatrics by her general practitioner with a 2-day history of blisters on her hands. Staphylococcal scalded skin syndrome was suspected, so intravenous flucloxacillin was started. All observations, including temperature, were within normal limits. Investigations showed normal full blood count and C reactive protein. Dermatology opinion was sought and further history revealed that on the day before the eruption appeared, she had helped to peel parsnips for Sunday lunch. She played in the garden all afternoon after completing culinary duties. On examination, there was background erythema with bullae on the dorsal aspect of the fingers, much worse on her dominant hand (figure 1). A diagnosis of phytophotodermatitis caused by parsnips was made. The antibioti...

Dec 14, 2014 04:00PM

MRI findings of radiation?associated angiosarcoma of the breast (RAS)

ConclusionClinical, mammographic, and sonographic findings of RAS are nonspecific and may be occult on conventional breast imaging; MRI findings of RAS include rapidly enhancing dermal and intraparenchymal lesions, some of which are low signal on T2 weighted imaging. J. Magn. Reson. Imaging 2014. (Source: Journal of Magnetic Resonance Imaging)

Dec 14, 2014 04:00PM

?? T?cell?rich variants of pityriasis lichenoides and lymphomatoid papulosis: benign cutaneous disorders to be distinguished from aggressive cutaneous ?? T?cell lymphomas

ConclusionsThe detection of a predominantly ?? T?cell phenotype in papular lymphoid?rich infiltrates in the absence of other lesions is not associated with a clinically aggressive course. ?? T?cell?rich variants of LyP and PL may reflect a spectrum of related conditions. This is a single academic centre retrospective chart review of a relatively small sample. (Source: British Journal of Dermatology)

Dec 14, 2014 04:00PM

Intractable abdominal pain in a healthy young man

A 23-year-old previously healthy man was admitted to our hospital due to intractable abdominal pain with haematemesis for 1 week. He also presented with fever and painful symmetric polyarthritis involving his wrists and ankles. Laboratory evaluation was unremarkable. CT of his abdomen disclosed remarkable segmental dilatation and wall thickening of the small intestine (figure 1). After 2 days, palpable purpura developed over the dorsal aspect of his feet and ankles (figure 2). A skin biopsy showed leucocytoclastic vasculitis, which is compatible with Henoch –Schönlein purpura (HSP). The abdominal pain and skin lesions resolved after intravenous corticosteroid therapy. The typical first symptom of HSP is purpuric skin lesions. However, up to 24% of patients with HSP hav...

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Dec 14, 2014 06:52AM

Ixekizumab linked to decrease in psoriasis-related sexual difficulties

AMSTERDAM ? Patient complaints of psoriasis-related sexual difficulties decreased significantly in response to treatment with the investigational biologic agent ixekizumab in a phase 2 dose-ranging study. Sexual problems attributed by psoriasis patients to their skin condition are a common,...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

Dec 14, 2014 05:51AM

Congress leaves SGR, Medicaid parity, ICD-10 undone

The year is ending on a sour note for physicians, as Congress is recessing without addressing the Medicare Sustainable Growth Rate formula or acting on a number of other doctors? priorities. Congress did not extend a pay increase for primary care physicians who serve Medicaid recipients, nor did...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

Dec 13, 2014 04:00PM

Biocompatibilities and biodegradation of poly(3-hydroxybutyrate- co -3-hydroxyvalerate)s produced by a model metabolic reaction-based system

Conclusion: Taken together, the results support the use of PHB and the random and putative block PHBVs produced in this study as potential biomaterials in tissue engineering applications for connective tissue, bone and dermal fibroblast reconstruction. (Source: BMC Microbiology)

Dec 13, 2014 04:00PM

Blistering disease: insight from the hemidesmosome and other components of the dermal-epidermal junction

Abstract The hemidesmosome is a specialized transmembrane complex that mediates the binding of epithelial cells to the underlying basement membrane. In the skin, this multiprotein structure can be regarded as the chief adhesion unit at the site of the dermal-epidermal junction. Focal adhesions are additional specialized attachment structures located between hemidesmosomes. The integrity of the skin relies on well-assembled and functional hemidesmosomes and focal adhesions (also known as integrin adhesomes). However, if these adhesion structures are impaired, e.g., as a result of circulating autoantibodies or inherited genetic mutations, the mechanical strength of the skin is compromised, leading to blistering and/or tissue inflammation. A particular clinical presentation emerges s...

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Dec 13, 2014 04:00PM

Biocompatibilities and biodegradation of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)s produced by a model metabolic reaction-based system

Conclusion: Taken together, the results support the use of PHB and the random and putative block PHBVs produced in this study as potential biomaterials in tissue engineering applications for connective tissue, bone and dermal fibroblast reconstruction. (Source: BioMed Central)

Dec 13, 2014 04:00PM

Redox-active cerium oxide nanoparticles protect human dermal fibroblasts from PQ-induced damage

Publication date: April 2015 Source:Redox Biology, Volume 4 Author(s): Claudia von Montfort , Lirija Alili , Sarah Teuber-Hanselmann , Peter Brenneisen Recently, it has been published that cerium (Ce) oxide nanoparticles (CNP; nanoceria) are able to downregulate tumor invasion in cancer cell lines. Redox-active CNP exhibit both selective pro-oxidative and antioxidative properties, the first being responsible for impairment of tumor growth and invasion. A non-toxic and even protective effect of CNP in human dermal fibroblasts (HDF) has already been observed. However, the effect on important parameters such as cell death, proliferation and redox state of the cells needs further clarification. Here, we present that nanoceria prevent HDF from reactive oxygen species (ROS)-induced cell death ...

Dec 13, 2014 12:01PM

Consider phototherapy for certain psoriasis patients

LAS VEGAS ? Psoriasis patients who are unresponsive to topical therapy, do not have psoriatic arthritis, and can make regular office visits may be candidates for successful treatment with phototherapy. A patient with type II skin and extensive plaque psoriasis could be treated with a targeted...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)

Dec 13, 2014 10:45AM

Patient complains of bugs on her skin ? could it be tox?

2.5 out of 5 stars Case 37-2014: A 35-Year-Old woman with Suspected Mite Infestation. Beach SR et al. N Engl J Med 2014 Nov 27;371:2115-2123. No abstract available This case ? part of the Journal‘s “Case Records of the Massachusetts General Hospital” series ? describes a 35-year-old woman had presented to the emergency department complaining of a parasitic skin infection: “During the 10 days before this presentation, she reported seeing white ‘granular balls,’ which she thought were mites or larvae, emerging from and crawling on her skin, sheets, and clothing and in her feces, apartment, and car, as well as having an associated pruritic rash.” She was referred to dermatology, but before the appointment was seen at another hospital, diagnosed...

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Dec 13, 2014 09:49AM

A systematic review on skin complications of bone-anchored hearing aids in relation to surgical techniques

Abstract A systematic review to study the skin complications associated with the bone-anchored hearing aid in relation to surgical techniques. The following databases have been searched: MEDLINE, EMBASE, the Cochrane Library , Google scholar and the PubMed. The literature search date was from January 1977 until November 2013. Randomised controlled trials and retrospective studies were included. Initial search identified 420 publications. Thirty articles met the inclusion criteria of this review. The most common surgical techniques identified were full-thickness skin graft, Dermatome and linear incision techniques. The result shows that dermatome technique is associated with higher rate of skin complications when compared to linear incision and skin graft techniques. Based on t...

Dec 13, 2014 08:15AM

Long-Lasting Responses under Treatment with Ipilimumab: An Argument against Maintenance Therapy?

We present three patients with metastatic melanoma who received ipilimumab after progression under chemotherapy. In all of these patients ipilimumab led to a long-term tumor control of at least 32 months. Interestingly, all of them developed severe autoimmune toxicity and ipilimumab treatment was discontinued after 1 respectively 2 cycles. The present cases demonstrate that a long-term response to ipilimumab can be achieved without maintenance therapy.Dermatology (Source: Dermatology)

Dec 13, 2014 08:14AM

Oxidative stress and substance P mediate psychological stress-induced autophagy and delay of hair growth in mice

Abstract Neuropeptide substance P (SP) and reactive oxygen species (ROS) have been demonstrated to play an important role in psychological stress-induced alteration of hair cycle, the underlying mechanism remains unknown. The present study aims to investigate possible contribution of SP and ROS in chronic restraint stress (CRS, a chronic psychological stress model) induced abnormal of hair cycle and induction of autophagy. Mouse CRS model was applied for 18 days with or without treatment antioxidant Tempol (a free radical scavenger) or SP receptor (NK1) antagonist (RP67580). After CRS procedure, hair growth cycle, oxidative stress markers and skin tissue autophagy levels were analyzed by ELISA or western blot. Our results revealed that CRS reduced body weight gain, distance of mo...

Dec 12, 2014 04:00PM

Rituximab therapy in pemphigus foliaceus: report of 12 cases and review of recent literature

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)