Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care

2262 Camino Ramon, San Ramon, CA 94583
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Patient Online Log in
(email staff to get your personal passcode)

* Patient Biopsy Results via LabCalls


MEDICAL DERMATOLOGY

Acne and Acne Scar

Excimer Laser for Psoriasis & Vitiligo

Keloid & Hypertrophic Scar Laser Therapy

Mohs Surgery for Skin Cancers

Nail Fungus GenesisPlus Laser Therapy

Photodynamic Therapy

Psoriasis & NBUVB Phototherapy

RadioTherapy Nonsurgical SRT-100 for Skin Cancer

Skin Allergy Patch Test

Sweating Disorder MiraDry for Hyperhidrosis

Wart Laser Therapy


COSMETIC DERMATOLOGY

Aesthetician Services
Microdermabrasion
 

Botox, Dysport & Xeomin

Cellulaze Cellulite Therapy

new! CoolSculpting

Facial Redness/Vein Laser Therapy

Fillers injection for Wrinkles

Fractional CO2 laser

new! Hair Transplant with Neograft

Laser Surgery Services
Acne/Pore reducing Laser
Collagen Stimulating Laser
Excimer Laser
Facial Veins laser
Hair Laser Removal
IPL Fotofacial
Melasma Laser
Nail Fungus Laser
Resurfacing Laser
Scar revision Laser
Tattoo Removal Lasers
VBeam Pulse Dye Laser
Wart Laser


Latisse

Leg Vein Laser Therapy & Asclera Sclerotherapy

Liposonix + Vaser Shape Nonsurgical Body Sculpting
 

Melasma and Pigmentation

Pore Size Reduction and Laser Rejuvenation

Sculptra Liquid Facelift

SideLaze Lift

Ulthera natural lift & skin tightening of face and neck


Related Websites
FaceUpLifting.com
iCellulaze.com
MoreHair4Me.com
SideLazeLift.com
SonixLipo.com


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925-328-0255

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* Review Dr. Ting's 717+ Q&A on RealSelf

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Fri, 22 Aug 2014 21:40:55 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Aug 22, 2014 01:13PM

Friday Feedback: Specialty Turf Wars

(MedPage Today) -- This week, Friday Feedback asks: How big a problem are turf wars in medical care and what are some solutions? (Source: MedPage Today Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Aug 22, 2014 10:45AM

Effect of Aloe vera application on the content and molecular arrangement of glycosaminoglycans during calcaneal tendon healing

ABSTRACT Although several treatments for tendon lesions have been proposed, successful tendon repair remains a great challenge for orthopedics, especially considering the high incidence of re?rupture of injured tendons. Our aim was to evaluate the pharmacological potential of Aloe vera on the content and arrangement of glycosaminoglycans (GAGs) during tendon healing, which was based on the effectiveness of A. vera on collagen organization previously observed by our group. In rats, a partial calcaneal tendon transection was performed with subsequent topical A. vera application at the injury site. The tendons were treated with A. vera ointment for 7 days and excised on the 7th, 14th, or 21st day post?surgery. Control rats received ointment without A. vera. A higher content of GAGs and a ...

Aug 21, 2014 04:00PM

Tolerance to egg proteins in egg?sensitized infants without previous consumption

ConclusionsIn egg?sensitized infants with EW SPT ?8 mm and/or EW sIgE ?8.36 KU/l, egg diagnostic OFC can be avoided as there is 94% probability of becoming positive. In the other patients, OFC should be performed safely and early to avoid unnecessary diets. (Source: Allergy)

Aug 21, 2014 04:00PM

Quercetagetin inhibits macrophage?derived chemokine in HaCaT human keratinocytes via the regulation of signal transducer and activator of transcription 1, suppressor of cytokine signalling 1 and transforming growth factor??1

ConclusionsThese results suggest that quercetagetin may be a potent inhibitor of the STAT1 signal, which could be a new molecular target for anti?inflammatory treatment, and may thus have therapeutic applications as an immune modulator in inflammatory diseases such as AD. (Source: British Journal of Dermatology)

Aug 21, 2014 12:15PM

First-trimester nonsystemic corticosteroid use and the risk of oral clefts in Norway.

CONCLUSIONS: Our data add to the suggestive but inconsistent findings for this association. PMID: 25127739 [PubMed - in process] (Source: Annals of Epidemiology)

Aug 21, 2014 11:21AM

Lilly Psoriasis Drug Succeeds in Late-Stage StudiesLilly Psoriasis Drug Succeeds in Late-Stage Studies

Eli Lilly and Co said its experimental psoriasis drug was found to be more effective in clearing skin than a generic treatment and a placebo in late-stage studies. Reuters Health Information (Source: Medscape Medical News Headlines)

Aug 21, 2014 09:43AM

State of the Union: Advances in Skin & Wound Care?The Journal and Clinical Symposium

No abstract available (Source: Advances in Skin and Wound Care)

Aug 21, 2014 09:43AM

Meaningful Use Audit Checklist

No abstract available (Source: Advances in Skin and Wound Care)

Aug 21, 2014 09:43AM

Arterial Disease Ulcers, Part 1: Clinical Diagnosis and Investigation

PURPOSE:To provide information regarding the clinical diagnosis, assessment, and investigations related to arterial disease ulcers of the lower extremity. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able to:1. Describe the etiology and pathophysiology of peripheral arterial disease (PAD) and arterial ulcers.2. Identify the clinical features of PAD and arterial ulcers as a result of arterial insufficiency of the lower limb.3. Compare assessment modalities to determine the extent of arterial insufficiency and appropriate interventions. (Source: Advances in Skin and Wound Care)

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Aug 21, 2014 09:13AM

Make the Diagnosis: Neck rash

(MedPage Today) -- A 45 year old patient in your clinic has diabetes, weighs 220 pounds, and is complaining of skin tags and a darkening velvety rash on her neck. She has recently started insulin therapy for diabetes, and currently takes no other medications. The patient is concerned that a necklace that she has been wearing every day for the last two years has caused the rash. What is the Diagnosis? (Source: MedPage Today Dermatology)

Aug 21, 2014 08:15AM

Can a Manicure Increase Skin Cancer Risk?Can a Manicure Increase Skin Cancer Risk?

A new study finds a link between frequent visits to the nail salon and skin cancer risk. Medscape Internal Medicine (Source: Medscape Dermatology Headlines)

Aug 21, 2014 01:43AM

The IOC Centres of Excellence bring prevention to sports medicine - Engebretsen L, Bahr R, Cook JL, Derman W, Emery CA, Finch CF, Meeuwisse WH, Schwellnus M, Steffen K.

The protection of an athlete's health and preventing injuries and illnesses in sport are top priorities for the IOC and its Medical Commission. The IOC therefore partners with selected research centres around the world and supports research in the field of... (Source: SafetyLit: All (Unduplicated))

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Aug 20, 2014 04:00PM

Paralytic rabies following cat scratch and intra-dermal anti-rabies vaccination

Vykuntaraju K Gowda, GV Basavaraja, Hamsa Reddy, Premalatha RamaswamyJournal of Pediatric Neurosciences 2014 9(2):154-155Only few reports of failure of intradermal postexposure prophylaxis for rabies following cat scratch exist in the published literature. We are reporting such a case in a 15-year-old girl. The child had category III cat scratch on her face. She presented with progressive paralysis, finally developing quadriplegia and respiratory paralysis. Typical hydrophobia and aerophobia were absent. She received intra-dermal anti-rabies cell culture vaccine. She did not receive anti-rabies immunoglobulin. The girl succumbed on the 10 th day of weakness. Diagnosis of rabies was confirmed by isolation of rabies virus RNA in cerebrospinal fluid and skin biopsy sample by reverse transcrip...

Aug 20, 2014 04:00PM

Expression of the T Cell?specific Adapter Protein in Human Tissues

Abstract T cell?specific adapter protein (TSAd) encoded by the SH2D2A gene is expressed in activated T cells, NK cells and endothelial cells, but its tissue expression has not yet been mapped. Here, we have defined the specificity of two commercially available anti?TSAd monoclonal reagents using peptide arrays. We found them to bind separate epitopes in the C?terminal part of TSAd. We then used immunohistochemistry to examine TSAd expression in various human lymphoid and non?lymphoid tissues. Immunostaining of adjacent tissue sections revealed that a substantial fraction of CD3?positive cells in normal lymphoid and non?lymphoid tissues expressed TSAd. In particular, essentially all intra?epithelial T cells appeared to coexpress TSAd. In addition, TSAd expression was observed ...

Aug 20, 2014 04:00PM

?? T cell?rich variants of pityriasis lichenoides and lymphomatoid papulosis: benign cutaneous disorders to be distinguished from aggressive cutaneous ?? T cell lymphomas

ConclusionsThe detection of a predominantly ?? T cell phenotype in papular lymphoid?rich infiltrates in the absence of other lesions is not associated with a clinically aggressive course. ?? T?cell?rich variants of LyP and PL may reflect a spectrum of related conditions. This is a single academic center retrospective chart review of a relatively small sample.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

A telephone based motivational interviewing intervention has positive effects on psoriasis severity and self?management ? A randomized controlled trial

ConclusionsA 3?month motivational interviewing intervention following CHT had positive overall effects on disease severity, self?efficacy, psoriasis knowledge and health behaviour change. This approach has the potential to be an important complement to medical management, self?management and patient education in psoriasis patients.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Aug 20, 2014 04:00PM

Peri?operative management of and recommendations for antithrombotic medications in dermatological surgery

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

Novel microdeletion in LOR causing autosomal dominant Loricrin keratoderma

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

Darier's disease can be complicated by generalised cutaneous candidiasis: a case?report.

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

Impact of smoking on response to systemic treatment in patients with psoriasis: a retrospective case?control study.

ConclusionsIn our retrospectively studied cohort smoking did not affect response to systemic treatment in psoriatic patients. A prospective study examining the complex relationship between smoking, psoriasis and response to systemic therapy is warranted to better explore this association.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

Fewer U.S. Teens Using Sunscreen, Study Finds

Warnings about sun exposure and skin cancer aren't getting through, experts say (Source: The Doctors Lounge - Oncology)

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Aug 20, 2014 04:00PM

Keloids in Rubinstein?Taybi syndrome: a clinical study

ConclusionsKeloids occur in 24% of individuals with RSTS, either spontaneously or after a minor trauma, usually starting in early puberty. Management schedules have disappointing results. RSTS is a Mendelian disorder with a known molecular basis, and offers excellent opportunities to study the pathogenesis of keloids in general and to search for possible treatments. (Source: British Journal of Dermatology)

Aug 20, 2014 04:00PM

Expression of programmed death?1 in skin biopsies of benign inflammatory vs. lymphomatous erythroderma

ConclusionsWhile PD?1 is expressed by CD4+ neoplastic T cells in SS, our results suggest that PD?1 is expressed mainly by activated dermal and epidermal CD8+ T cells in EID. Expression of PD?1 by > 50% of CD4+ T cells and expression of CD7 by ? 20% of the infiltrating T cells strongly support a diagnosis of SS in skin biopsies of patients with erythroderma. (Source: British Journal of Dermatology)

Aug 20, 2014 11:00AM

Botox Tested on Stomach Cancer in Mice

Preliminary research suggests the wrinkle treatment might silence critical nerves that support tumors (Source: The Doctors Lounge - Oncology)

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Aug 20, 2014 10:00AM

Study identifies protein that helps prevent active tuberculosis in infected patients

A UCLA-led study has identified a protein that appears to play a key role in protecting people infected with Mycobacterium tuberculosis ? the bacterium that causes tuberculosis ? from developing the active form of the disease. The protein, interleukin-32, was discovered to be one biomarker of adequate host defense against TB. The discovery could help doctors identify people who are at the greatest risk for the highly contagious and potentially fatal lung disease, and it could point the way toward new treatment strategies for TB. The study, conducted in partnership with researchers from Harvard University School of Public Health and the University of Michigan School of Medicine, was published in the Aug. 20 online edition of the journal Science Translational Medicine. The findings ...

Aug 19, 2014 11:00PM

Health Tip: Soothing Psoriasis on the Feet

Title: Health Tip: Soothing Psoriasis on the FeetCategory: Health NewsCreated: 8/20/2014 7:35:00 AMLast Editorial Review: 8/20/2014 12:00:00 AM (Source: MedicineNet Skin General)

Aug 19, 2014 11:00PM

Drug Restores Hair in Alopecia Patients: FAQ

Title: Drug Restores Hair in Alopecia Patients: FAQCategory: Health NewsCreated: 8/20/2014 11:00:00 AMLast Editorial Review: 8/20/2014 12:00:00 AM (Source: MedicineNet Skin General)

Aug 19, 2014 04:00PM

Letter to the Editor concerning the article ?Geographical ancestry is a key determinant of epidermal morphology and dermal compotition?

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 19, 2014 04:00PM

Drug survival is not significantly different between biologics in patients with psoriasis vulgaris: a single?centre database analysis

ConclusionsThere was no significant difference in drug survival, mean ?PASI or Skindex?29 response at weeks 12 or 52 between the biologics or between the naive and non?naive groups. Treatment termination was due mostly to nonresponse. Sequential treatment with the available biologics can be effective. (Source: British Journal of Dermatology)

Aug 19, 2014 04:00PM

Sea, carbohydrates, and clotting: a triad on the road of drug discovery.

This report intends to prove the promising combination of the triad sea-carbohydrates-clotting in drug discovery of the cardiovascular field. PMID: 25138087 [PubMed - as supplied by publisher] (Source: Mini Reviews in Medicinal Chemistry)

Aug 19, 2014 04:00PM

Detection of potentially skin sensitizing hydroperoxides of linalool in fragranced products.

In conclusion, very low levels of linalool hydroperoxide in fragranced products may originate from raw materials, but we found no evidence for oxidation during storage of products. The levels detected are orders of magnitude below the levels inducing sensitization in experimental animals, and these results therefore do not substantiate a causal link between potential hydroperoxide formation in cosmetics and positive results of patch tests. PMID: 25138721 [PubMed - as supplied by publisher] (Source: Analytical and Bioanalytical Chemistry)

Aug 19, 2014 07:15AM

Dermira Completes $51 Million Financing and Expands Management Team and Board of Directors

REDWOOD CITY, Calif.--(Healthcare Sales & Marketing Network)--Dermira, a specialty biopharmaceutical company focused on bringing innovative and differentiated medical dermatology products to dermatologists and their patients, today announced that it has co... Biopharmaceuticals, Dermatology, Venture Capital, PersonnelDermira (Source: HSMN NewsFeed)

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Aug 19, 2014 07:12AM

Aqua Pharmaceuticals, LLC Welcomes Nathan Mitchell as Senior Director, Marketing

WEST CHESTER, Pa.--(Healthcare Sales & Marketing Network)--West Chester-based Aqua Pharmaceuticals, an Almirall company, today announces the addition of Nathan Mitchell as Senior Director, Marketing. In this role, Mitchell will be responsible for strategiz... Biopharmaceuticals, Dermatology, PersonnelAqua Pharmaceuticals, Almirall (Source: HSMN NewsFeed)

Aug 19, 2014 06:44AM

Could This Rash Mean Malignancy?Could This Rash Mean Malignancy?

Jonathan Kay describes a patient with an extensive rash that initially suggested dermatomyositis but turned out to auger something more serious. Medscape Rheumatology (Source: Medscape Today Headlines)

Aug 18, 2014 05:43PM

Make the Diagnosis: Backyard arm

(MedPage Today) -- An otherwise healthy 36-year-old man presents with an asymptomatic rash. He reports he was doing spring cleaning, including emptying his woodshed, mowing his lawn, and clearing some brush from his backyard. ? He is otherwise healthy, and takes no medications. ? He has no fevers, joint pains, or other systemic symptoms. (Source: MedPage Today Dermatology)

Aug 18, 2014 04:16PM

Turning the Tide Against Inappropriate AntibioticsTurning the Tide Against Inappropriate Antibiotics

We seem to be fulfilling Alexander Fleming's direst worry, but do people really think about the greater good when prescribing antibiotics? Medscape Infectious Diseases (Source: Medscape Dermatology Headlines)

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Aug 18, 2014 04:00PM

Factors predicting the development of pressure ulcers in an at?risk population who receive standardized preventive care: secondary analyses of a multicentre randomised controlled trial

ConclusionsDespite the standardized preventive measures they received, hospitalized patients with non?blanchable erythema, urogenital disorders and a higher body temperature were at increased risk for developing pressure ulcers. Relevance to Clinical PracticeImproved identification of at?risk patients can be achieved by taking into account specific predictive factors. Even if preventive measures are in place, continuous assessment and tailoring of interventions is necessary in all patients at risk. Daily skin observation can be used to continuously monitor the effectiveness of the intervention. (Source: Journal of Advanced Nursing)

Aug 18, 2014 04:00PM

Lack of association between the 389C>T polymorphism (rs769217) in the catalase (CAT) gene and the risk of vitiligo: An update by meta?analysis

ConclusionsOur results suggest that 389C>T may not contribute to vitiligo susceptibility. However, larger primary studies with the consideration of gene?environment and gene?gene interactions are still required to further evaluate the interaction of CAT gene polymorphism with vitiligo susceptibility. (Source: Australasian Journal of Dermatology)

Aug 18, 2014 04:00PM

The Therapeutic Potential of a C?X?C Chemokine Receptor type 4 (CXCR?4) Antagonist on Hypertrophic Scarring in vivo

In this study, the inhibitory effect of CXCR4 antagonist CTCE?9908 on dermal fibrosis was determined in vivo using a human HTS?like nude mouse model, in which split?thickness human skin is transplanted into full thickness dorsal excisional wounds in athymic mice, where these wounds subsequently develop fibrotic scars that resemble human HTS as previously described. CTCE?9908 significantly attenuated scar formation and contraction, reduced the accumulation of macrophages and myofibroblasts, enhanced the remodeling of collagen fibers, and down?regulated the gene and protein expression of fibrotic growth factors in the human skin tissues. These findings support the potential therapeutic value of CXCR4 antagonist in dermal fibrosis and possibly other fibroproliferative disorders. (So...

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Aug 18, 2014 04:00PM

Prevalence and characteristics of chemical intolerance: a Japanese population-based study.

Authors: Azuma K, Uchiyama I, Katoh T, Ogata H, Arashidani K, Kunugita N Abstract Abstract Population-based cross-sectional study was performed to estimate the prevalence of chemical intolerance and to examine the characteristics of the sample. A web-based survey was conducted that included 7245 adults in Japan. The criteria for chemical intolerance proposed by Skovbjerg yielded a prevalence of 7.5% that was approximately consistent with that reported from a Danish population-based survey. Female gender, older age and renovation in the house during the past 7 years were positively associated with chemical intolerance. Improvements in the condition were observed with daily ventilation habits. Medical history of atopic dermatitis, allergic rhinitis, food allergy, multiple chemical s...

Aug 18, 2014 11:08AM

Questions About Who Should Perform In-Office SurgeriesQuestions About Who Should Perform In-Office Surgeries

A study of Medicare billing found that many dermatology procedures were done by nurse practitioners and physician assistants Kaiser Health News (Source: Medscape Medical News Headlines)

Aug 18, 2014 10:03AM

Intralesional Mycobacterium W Vaccine for Anogenital WartsIntralesional Mycobacterium W Vaccine for Anogenital Warts

Intralesional Mycobacterium w vaccine appears to be as effective as imiquimod cream for treating anogenital warts, researchers from India report. Reuters Health Information (Source: Medscape Dermatology Headlines)

Aug 18, 2014 09:00AM

Nasal reconstruction: a dermatological surgeon's approach to recreating the 'aesthetic king' of the central face.

Authors: Hussain W PMID: 25124306 [PubMed - in process] (Source: The British Journal of Dermatology)

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Aug 18, 2014 09:00AM

Nasal anatomy for the dermatological surgeon.

This article is intended to serve as an overview of the anatomy of the nose for dermatologists and dermatological surgeons. Areas of clinical relevance are emphasized with examples. PMID: 25124307 [PubMed - in process] (Source: The British Journal of Dermatology)

Aug 18, 2014 09:00AM

Reconstructing the nasal dorsum.

Authors: Vinciullo C Abstract The skin of the nasal dorsum and bridge is more forgiving in terms of reconstructive options. Individual differences in skin laxity, nasal length and sebaceous composition impact on reconstructive choice as do the size, depth and exact location of the surgical defect. For many, if not all, defects in this area there are multiple different reconstructive options available all of which can result in equivalent and excellent results. Oftentimes there is no clear advantage of one repair over another and the choice becomes one of personal preference based on experience. No proscriptive approach or algorithm can be usefully applied in this setting. Key considerations include the location of the defect (distal vs. proximal nasal dorsum), the position of the d...

Aug 18, 2014 09:00AM

Repair of the nasal sidewall.

Authors: Salmon PJ Abstract Repair of the nasal sidewall after skin cancer excision is generally best approached with the use of local flaps for aesthetic reasons. The sidewall may be divided into upper and lower sections and defects described as small, medium or large. In this section I will review the flaps that I feel make best use of adjacent tissue reservoirs allowing aesthetic placement of incisions while protecting free margins and function, and that reward the operator with reliably superior results for the patient. PMID: 25124309 [PubMed - in process] (Source: The British Journal of Dermatology)

Aug 18, 2014 09:00AM

Reconstructing the nasal tip.

Authors: Stigall L, Zitelli J Abstract Given the intricate contours of adjacent concavities and convexities, the limited area from which to recruit similar skin, and variable areas of skin thickness, elasticity and adnexal density, reconstruction of the nasal tip is a challenging process. When approaching nasal reconstruction we have often found it helpful to partition defects into two subgroups: those that fall within the upper two-thirds of the nose and those that fall within the lower third. Within this framework of the lower third, we present our reconstructive approach to surgical defects of the nasal tip. PMID: 25124310 [PubMed - in process] (Source: The British Journal of Dermatology)

Aug 18, 2014 09:00AM

The reconstruction of the nasal ala with interpolated flaps from the cheek and forehead: design and execution modifications to improve surgical outcomes.

Authors: Cook JL Abstract The nasal ala, critically important in the function and appearance of the central face, has significant reconstructive demands given the lack of suitable adjacent donor tissue that can be used to repair all but the smallest surgical defects in this area. Interpolated flaps from the forehead and cheek have long been ideal reconstructive alternatives for the repair of larger or more difficult alar wounds, and with the design and execution modifications described here, the dermatological surgeon can offer more appropriate restoration of this critically important aesthetic unit. PMID: 25124311 [PubMed - in process] (Source: The British Journal of Dermatology)

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Aug 18, 2014 02:00AM

University of Texas Researchers Reveal a Portable Cancer Detection Device with the Potential to Significantly Reduce the Number of Skin Biopsies Sent to Dermatopathologists

Team of bioengineers succeeds in putting three different imaging technologies into a handheld probe that could be used by physicians to assess skin lesions in their offices Dermatopathologists and pathology practice administrators will be keenly interested in a new, hand-held diagnostic device that is designed to reduce the need for skin biopsies. Because of high volume […] (Source: Dark Daily)

Aug 17, 2014 11:00PM

Early Research With Drug Restores Hair in Patients With Alopecia

Title: Early Research With Drug Restores Hair in Patients With AlopeciaCategory: Health NewsCreated: 8/17/2014 2:35:00 PMLast Editorial Review: 8/18/2014 12:00:00 AM (Source: MedicineNet Skin General)

Aug 17, 2014 04:00PM

Evidence?Based Guidelines for Laboratory Screening for Infectious Diseases Before Initiation of Systemic Immunosuppressive Agents in Patients With Autoimmune Bullous Dermatoses

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 17, 2014 04:00PM

Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool

Conclusion. After 16.8 years, 51–73% of JDM patients had active disease. Disease activity by the PRINTO criteria and MDAAT were moderately to highly associated with most other disease characteristics and was predicted by early damage. (Source: Rheumatology)

Aug 17, 2014 04:00PM

Rituximab therapy in patients with refractory dermatomyositis or polymyositis: differential effects in a real-life population

Conclusion. In a real-life population of patients with severe, refractory PM or DM, objective improvement was seen in the majority of patients with regard to CPK and lung function tests, and glucocorticoids could be reduced. In contrast to the subgroup with DM, where one cycle of RTX appeared sufficient, patients with anti-synthetase syndromes commonly experienced flares necessitating RTX re-treatment. Infections are of concern. (Source: Rheumatology)

Aug 17, 2014 04:00PM

Prevalence of tinea pedis in psoriasis, compared to atopic dermatitis and normal controls ? a prospective study

Summary There are discrepancies in the literature regarding the prevalence of tinea pedis in psoriasis. The aim of this investigation was to conduct a cross?sectional study of the prevalence of tinea pedis in psoriasis compared to atopic dermatitis patients and normal controls. We enrolled 232 psoriatic patients, 190 atopic dermatitis patients and 202 normal controls, between the years 2010 and 2013. The prevalence of tinea pedis was 13.8% in psoriasis patients, not significantly different from that in atopic dermatitis patients 8.4% (P = 0.092)), but significantly higher than in normal controls 7.4% (P = 0.043). Both gender and age affected the prevalence of tinea pedis in psoriasis and normal controls, while only age affected the prevalence of tinea pedis in atopic dermatitis. Rega...

Aug 17, 2014 04:00PM

Using the Peng flap for a wide dorsal nasal defect

Summary Reconstructions of large surgical defects of the central part of the nose pose a challenge for the surgeon due to its cosmetically prominent location. Treatment options include second intention healing, full?thickness skin grafts and various local flaps. In the present case the ?Peng flap? was used for the reconstruction of a 3.1 × 7 cm sized deep defect of the convex curve of the central nasal area in a 66?year?old woman. The Peng flap was performed as single?stage procedure without complications. Good cosmetic outcome was provided by the use of adjacent skin from the lax perinasal area, the placement of the scar lines between facial cosmetic units, and the excellent tissue match for the sebaceous nasal skin. Considering the few complications of a single?stage proce...

Aug 17, 2014 04:00PM

Wheat-dependent exercise-induced anaphylaxis: a retrospective case review from a tertiary hospital

Conclusions With the emergence of wheat allergy in East Asian countries, WDEIA has become an important condition for physicians and Singapore is no exception. Under-recognition combined with life-threatening symptoms warrants better public awareness measures. In addition, further studies are necessary to identify possible unique genetic and environmental exposures that could explain the inter-regional differences of WDEIA. (Source: Postgraduate Medical Journal)

Aug 17, 2014 04:00PM

Cutaneous leishmaniasis in a returning UK traveller

Introduction The Leishmaniases are diseases caused by protozoan parasites from more than 20 Leishmania (L.) species (order Kinetoplastida) that are transmitted to humans by the bites of infected female Phlebotomine and Lutzomyia sandflies. There are three main forms of the disease: cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis and visceral leishmaniasis or kala-azar.1 It is estimated that 0.7–1.2 million of new CL cases and 0.2–0.4 million of new visceral leishmaniasis cases occur each year worldwide.1 CL is classified into Old and New World Cutaneous Leishmaniasis (NWCL) depending on the geographical region where the infection was acquired. NWCL is commonly caused by the L. mexicana complex and L. Viannia subgenus. The majority of CL cases occur in Afghanistan, Alg...

Aug 17, 2014 04:00PM

Health threat associated with Caucasian giant hogweeds: awareness among doctors and general public in Poland.

Conclusions: Public and medical attention needs to be raised as to the threats associated with giant hogweeds, particularly in countries that are highly infested with these plants. PMID: 25133324 [PubMed - as supplied by publisher] (Source: Cutaneous and Ocular Toxicology)

Aug 16, 2014 04:00PM

An improved dual approach to post bariatric contouring - Staged liposuction and modified medial thigh lift: A case series

Conclusions: The modified 'T' incision with staged liposuction is described. We have found the technique to be useful for a variety of different thighs. It is a reproducible method for contouring the medial thigh in MWL patients. In this series, our overall complications were low, and no seromas occurred. (Source: Indian Journal of Plastic Surgery)

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Aug 16, 2014 04:00PM

Painful nodules on the soles in a 9-year-old boy

A 9-year-old child was referred to our paediatric dermatology unit for a temporary walking impairment because of painful lesions on the soles of both his feet. The lesions had erupted the day before, after prolonged walking with rubber boots. Physical examination showed multiple, reddish to purple, non-confluent, painful nodules on the soles of both feet (figure 1). The child was in general good condition, without fever. The laboratory tests performed (complete blood count, erythrocyte sedimentation rate, serum reactive protein, antinuclear antibody) were within normal limits. Histological examination showed a dense neutrophilic infiltrate around and within the eccrine cells. The diagnosis of palmoplantar eccrine hidradenitis (PEH) was made.1 PEH is an uncommon condition described for the ...

Aug 16, 2014 04:00PM

Sodium Pentaborate Pentahydrate and Pluronic Containing Hydrogel Increases Cutaneous Wound Healing In Vitro and In Vivo.

Authors: Do?an A, Demirci S, Ca?layan AB, K?l?ç E, Günal MY, Uslu U, Cumbul A, Sahin F Abstract After a disruption of skin integrity, the body produces an immediate response followed by a functional and comparable regeneration period, referred to as wound healing. Although normal wounds do not need much attention during the healing period, chronic (non-healing) wounds are the major challenge of current dermatological applications. Therefore, developing new, safe, and effective wound healing drugs has always been an attractive area of international research. In the current study, sodium pentaborate pentahydrate (NaB), pluronics (Plu; F68 and F127), and their combinations were investigated for their wound healing activities, using in vitro and in vivo approaches. The results re...

Aug 16, 2014 10:40AM

Alpine climate treatment of atopic dermatitis: a systematic review

This article is protected by copyright. All rights reserved. (Source: Allergy)

Aug 15, 2014 04:00PM

Secukinumab Administration by Pre?filled Syringe: Efficacy, Safety, and Usability Results from a Randomized Controlled Trial in Psoriasis (FEATURE)

ConclusionsSecukinumab administration by PFS was effective, with an acceptable safety profile and high usability. The PFS provides a reliable, convenient form of secukinumab administration in subjects with moderate?to?severe plaque psoriasis.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 15, 2014 04:00PM

Comparison of long?term drug survival and safety of biologic agents in patients with psoriasis vulgaris

ConclusionsUstekinumab has a significantly longer drug survival than the anti?TNF? agents. Switch from one biologic to another is associated with an impairment of drug survival. Preventing the loss of efficacy is a major area of medical need in the biologic therapy of psoriasis and the strategies that improve drug survival should be further investigated.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Aug 15, 2014 04:00PM

Onychomadesis: Literature Review

This article summarizes these key culprit associations, postulates the pathogenesis of nail matrix arrest and summarizes the clinical outcomes. MethodsWe conducted a retrospective review of the cases of onychomadesis reported from January 1960 until March 2013. Using the pubmed database, the literature was searched using the following terms: ?Onychomadesis? and ?Proximal Nail shedding?. As well, an OVID search was carried out using the same terms. ResultsA total of 56 articles have been published including our previously reported series of idiopathic onychomadesis. Articles pertaining only to Beau's lines and not true onychomadesis were excluded. Onychomadesis has been associated with autoimmune disease, other major medical illness, neonatal illness, medication induced and infectio...

Aug 15, 2014 04:00PM

Subluminescence photodynamic therapy of recalcitrant foot warts

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Aug 15, 2014 04:00PM

Comparison of anatomical locations of cutaneous melanoma in men and women: a population?based study in France

ConclusionsSex differences in occupational and leisure time ultraviolet exposure, clothing (including shoes), hairstyle, and side and photo exposure in cars could explain these results. General preventive messages could be completed by sex?specific advice for melanoma prevention. (Source: British Journal of Dermatology)

Aug 15, 2014 04:00PM

Prevalence and incidence of hand eczema in adolescence: report from BAMSE ? a population?based birth cohort

ConclusionsAt the age of 16 years, the 1?year prevalence of hand eczema was substantial, with an incidence rate of the same magnitude as in adults. Female predominance was seen in adolescence. It is preferable that the occurrence of hand eczema is reported by adolescents themselves, as they are the ones most aware of their symptoms. (Source: British Journal of Dermatology)

Aug 15, 2014 12:30PM

Derms Want NP/PA Practice Limits (CME/CE)

(MedPage Today) -- NPs and PAs who bill Medicaid as independent practitioners are more likely to bill for a dermatology visit than for any other office-based service -- so much so that in 2012, 55% of their Medicaid billings were for derm codes, to which dermatologists claim scope of practice violations. (Source: MedPage Today Public Health)

Aug 15, 2014 11:29AM

Identification of Malassezia species in the facial lesions of Chinese seborrhoeic dermatitis patients based on DNA sequencing

Summary The genus Malassezia is important in the aetiology of facial seborrhoeic dermatitis (FSD), which is the most common clinical type. The purpose of this study was to analyse the distribution of Malassezia species in the facial lesions of Chinese seborrhoeic dermatitis (SD) patients and healthy individuals. Sixty?four isolates of Malassezia were isolated from FSD patients and 60 isolates from healthy individuals. Sequence analysis of the internal transcribed spacer (ITS) region was used to identify the isolates. The most frequently identified Malassezia species associated with FSD was M. furfur (76.56%), followed by M. sympodialis (12.50%) and M. japonica (9.38%). The most frequently isolated species in healthy individuals were M. furfur (61.67%), followed by M. sympodialis (25.00%)...

Aug 15, 2014 08:40AM

The IOC Centres of Excellence bring prevention to Sports Medicine.

Authors: Engebretsen L, Bahr R, Cook JL, Derman W, Emery CA, Finch CF, Meeuwisse WH, Schwellnus M, Steffen K Abstract The protection of an athlete's health and preventing injuries and illnesses in sport are top priorities for the IOC and its Medical Commission. The IOC therefore partners with selected research centres around the world and supports research in the field of sports medicine. This has enabled the IOC to develop an international network of expert scientists and clinicians in sports injury and disease prevention research. The IOC wants to promote injury and disease prevention and the improvement of physical health of the athlete by: (1) establishing long-term research programmes on injury and disease prevention (including studies on basic epidemiology, risk factors, inju...

Aug 15, 2014 07:59AM

First biosimilar monoclonal antibody distribution licence secured

Mundipharma International Corporation Limited has announced that it has secured a distribution licence from Celltrion Healthcare Hungary Kft for Remsima (infliximab). (Source: Pharmacy Europe)

Aug 15, 2014 02:25AM

Pathogenesis and Treatment of Acne and Rosacea

(Source: Springer Medicine titles)

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Aug 14, 2014 11:00PM

Choose Wrinkle Treatments Wisely, FDA Advises

Title: Choose Wrinkle Treatments Wisely, FDA AdvisesCategory: Health NewsCreated: 8/14/2014 4:35:00 PMLast Editorial Review: 8/15/2014 12:00:00 AM (Source: MedicineNet Skin General)

Aug 14, 2014 04:00PM

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts

Conclusions: DHLA not only acts as an antioxidant but also an antifibrotic since it has the ability to reverse the profibrotic phenotype of SSc dermal fibroblasts. Our study suggests that thiol antioxidants, including NAC and LA/DHLA, could be beneficial for patients with SSc. (Source: Arthritis Research and Therapy)

Aug 14, 2014 04:00PM

Pseudoporphyria following self-medication with chlorophyll.

Authors: Rossi E, Borchard K, Cole JM Abstract Two cases of pseudoporphyria are described in which the clinical features of porphyria cutanea tarda occurred in the absence of abnormalities in porphyrin metabolism. Both patients presented with skin fragility and bullae on the dorsal aspect of the hands. The patients consumed a commercial liquid chlorophyll drink in which we detected fluorescent compounds with characteristics typical of previously described chlorophyll derived photosensitisers. PMID: 25123581 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology)

Aug 14, 2014 04:00PM

Generalised hyperpigmentation caused by ectopic adrenocorticotropic hormone syndrome with recurrent thymic neuroendocrine carcinoma.

Authors: Moon HR, Won CH, Chang SE, Lee MW, Choi JH, Moon KC Abstract Ectopic adrenocorticotropic hormone (ACTH) syndrome is a rare cause of generalised hyperpigmentation. The clinical features are due to the excessive ectopic secretion of adenocorticotropin by diverse neuroendocrine or non-endocrine tumours. Here, we describe a rare case of ectopic ACTH syndrome developing from recurring thymic neuroendocrine carcinoma, which first presented as generalised hyperpigmentation. PMID: 25123488 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology)

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Aug 14, 2014 12:27PM

'Top' Dermatologist Indicted for Healthcare Fraud'Top' Dermatologist Indicted for Healthcare Fraud

A Northern Virginia dermatologist has been charged with intentionally misdiagnosing and performing surgery for skin cancer. Medscape Medical News (Source: Medscape Medical News Headlines)

Aug 14, 2014 04:59AM

Case report: misdiagnosed olecranon bursitis: pyoderma gangrenosum

Pyoderma gangrenosum (PG) is a rare inflammatory and ulcerative disorder of the skin.7 Despite the name, PG is not an infectious process.28 It is instead a neutrophilic dermatosis characterized by neutrophil-predominant cutaneous infiltrates. It is manifested clinically as an inflammatory papule or pustule that progresses to a painful ulcer with a well-defined erythematous to violaceous border and a purulent base.7,17 Nonspecific laboratory findings include leukocytosis, elevated erythrocyte sedimentation rate, and elevated C-reactive protein. (Source: Journal of Shoulder and Elbow Surgery)

Aug 14, 2014 01:54AM

A reticulated and pruriginous rash in a 35-year-old woman

A 35-year-old white woman presented with a 4-week history of a pruritic and symmetrical rash on the upper aspect of the abdomen and torso, stretching to the axillae. The physical examination revealed multiple urticarial erythematous papules, vesicles, and excoriations that were associated with hyperpigmentation with a reticular pattern (Figs 1 and 2). The patient reported similar recurrent episodes in the previous 6 years, especially during the summer. She followed a sugar-free diet recommended by a homeopath, and she was otherwise healthy. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Erythematous lesions on the trunk and upper extremities

An 84-year-old man presented with a 2-month history of asymptomatic erythematous nodules on his left wrist and flank (Fig 1) and an erythematous plaque on his right shoulder (Fig 2). His medical history included nonmelanoma skin cancer and prostate cancer. Two years earlier, the patient had also been diagnosed with multiple myeloma after undergoing radiotherapy, and he had undergone 2 cycles of melphalan and prednisone; however, he discontinued chemotherapy 1 year earlier because of severe fatigue. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Topical antimicrobial acne treatment tolerability: A meaningful factor in treatment adherence?

Adherence to dermatologic treatment is estimated to range from 55% to 66%1 but is as low as 45% for daily application of topical antimicrobial acne treatments.2 Poor adherence may be the most important factor in acne treatment failure.3 Dogma suggests that irritation and poor tolerability reduce patients' adherence to treatment. Is there evidence to support this dogma? (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Trichoblastoma with dermoscopic features of a malignant tumor: Three cases

Case 1 was a 70-year-old man who presented with an erythematous 1.2-cm frontal nodule that had appeared recently (Fig 1, A). Case 2 was a 68-year-old woman who presented with a left temporal sebaceous nevus, associated with a recent onset of an overlying nodular skin lesion that was 2.0 × 0.7 cm (Fig 2, A). Case 3 was a 57-year-old woman who presented with a pigmented nodular lesion of unknown onset on her right shoulder (Fig 3, A). (Source: Journal of the American Academy of Dermatology)

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Aug 14, 2014 01:54AM

Extraosseous extension of multiple myeloma: A cutaneous herald to systemic disease

To the Editor: Cutaneous involvement of multiple myeloma is an extremely rare manifestation, typically presenting as an extraosseous extension to the skin.1 Presentation of these cutaneous lesions occurs more often in late stage multiple myeloma with a high tumor burden.2 A single-center retrospective study reported a 2.3% incidence of extramedullary and extraosseous tumor at the time of multiple myeloma diagnosis. Furthermore, cutaneous appearance and histopathology do not predict systemic disease and should alert the dermatologist to a need for further evaluation. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Periungual Bowen disease mimicking chronic paronychia and diagnosed by dermoscopy

A 75-year-old woman, with Fitzpatrick skin phototype I/II and a history of nonmelanoma skin cancer presented with a scaly, fissured, erythematous, fairly well demarcated patch involving the periungual skin of the left index finger (Fig 1). The lesion had persisted for >1 year despite the use of antibiotic and corticosteroid ointments. The patient was immunocompetent, an exsmoker, with no reported history of arsenic ingestion, trauma, burns, or ionizing radiation to the site. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Cheilitis and urticaria associated with stannous fluoride in toothpaste

To the Editor: A 55-year-old woman presented with recurrent idiopathic urticaria and cheilitis. Her symptoms began 2 years ago following dental work, with intermittent lip swelling and daily hives occurring over 10 months. She received 5- to 7-day tapered courses of 40 mg prednisone on 8 occasions during this time, and her symptoms ultimately remitted spontaneously. Prior allergy workup for urticaria, including patch testing (via TRUE test) was mildly positive only for thimerosal and fragrance. Prick testing for environmental allergens was negative. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Solar urticaria to visible light triggered by light-emitting diode therapy

We report a case of solar urticaria to visible light induced by LED therapy. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Distinctive cutaneous findings due to a rare complication from a warming device

To the Editor: Perioperative hypothermia is a well-known complication of general anesthesia and has been associated with numerous adverse outcomes: increased intraoperative blood loss, surgical wound infections, cardiac events, and duration of hospitalization. Maintaining patients in perioperative normothermia has become a routine practice with forced-air warming (FAW) devices, such as the Bair Hugger warming blanket (Arizant Healthcare, Eden Prairie, MN), a commonly used device. These devices are generally very safe and complications have largely been limited to misuse, such as directly blowing of warm air onto a patient without a blanket. (Source: Journal of the American Academy of Dermatology)

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Aug 14, 2014 01:54AM

Umbilical endometriosis elucidates cause of recurrent pneumothorax

We report a case of both cutaneous and thoracic endometriosis in the absence of surgery or prior endometriosis. Cutaneous findings secured the diagnosis of catamenial pneumothorax. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Reactive hemophagocytic syndrome in a patient with adult-onset Still disease

To the Editor: A healthy 37-year-old woman presented with a 2-week history of fever, arthralgias affecting knees and wrists, and an evanescent rash. The rash presented every day and favored the trunk, extremities, and face (Fig 1, A). Clinically, she had erythematous macules and papules scattered over her trunk, neck, and extremities, which exhibited the Koebner phenomenon. There was no evidence of pharyngitis, cervical lymphadenopathy, hepatosplenomegaly, pleuritis, or pericarditis on physical examination. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Generalized granuloma annulare after varicella infection: Wolf isotopic response?

To the Editor: The etiopathogenesis of granuloma annulare (GA) is unknown, but a delayed-type hypersensitivity reaction to an unknown antigen has been hypothesized. Several inciting factors have been reported, including trauma, ultraviolet radiation, and viral infections.1 Among the latter, GA developing at the site of previous herpes zoster (HZ) has frequently been reported in a Wolf isotopic response (WIR).1-3 However, GA developing after varicella infection, to the best of our knowledge, has not been reported except in a single report of localized GA developing 6 weeks after uncomplicated varicella in a 4-year-old child. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Iotaderma #248

(Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Photo-induced Stevens-Johnson syndrome

To the Editor: A 19-year-old woman with no past medical history developed a phototoxic rash with progression to Stevens-Johnson Syndrome (SJS) due to ciprofloxacin therapy for a recent vaginal infection. The patient completed a 10-day course of ciprofloxacin and received a 1-time dose of fluconazole on the 10th day of treatment; she was on no other medications and no other risk factors for SJS were present. The day after treatment completion, a red rash concentrated on her chest developed. She complained of difficulty and painful swallowing, which prompted her to visit our emergency department (ED). (Source: Journal of the American Academy of Dermatology)

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Aug 14, 2014 01:54AM

Subcorneal pustular dermatosis associated with infection

To the Editor: Subcorneal pustular dermatosis (SPD) or Sneddon-Wilkinson disease is a rare, chronic, and relapsing skin disorder, consisting of a symmetric sterile pustular eruption that primarily involves trunk and large skin folds. Flaccid, subcorneal pustules are half-filled with pus with a hypopyon-like appearance, containing polymorphonuclear neutrophils. The pathophysiology is unknown, but common associations include monoclonal IgA paraproteins, inflammatory bowel disease, and rheumatoid arthritis. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Pili multigemini/trichofolliculoma-like organoid nevus

To the Editor: We introduce a distinctive form of epidermal nevus of the ?organoid? type that we refer to as ?pili multigemini/trichofolliculoma-like organoid nevus.? Our patient is a healthy 6-year-old Latino girl born with a large, discrete patch of scalp alopecia that has remained unchanged, except for proportionate scalp growth. Her history and physical examination reveals normal findings, without cutaneous or dental abnormalities. The family history is unremarkable. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Peripheral facial palsy after topical photodynamic therapy for facial actinic keratoses

To the Editor: A 64-year-old man presented with multiple actinic keratoses (AK) in sun-exposed skin. Previous treatments included cryotherapy and a single treatment with topical photodynamic therapy (PDT) to frontal AK leading to partial response. We performed a second treatment with topical methyl-aminolevulinate (MAL) PDT to AK on the left side of the forehead, temple, cheek, and jaw. We applied a total amount of 2 g of MAL cream over a treatment field of about 120 cm2, which was kept under occlusive dressing for 3 hours. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

A rapidly progressive and fatal case of atypical acute generalized exanthematous pustulosis

To the Editor: A 78-year-old African American woman with metabolic syndrome presented with skin sloughing for 2 days. She had no history of skin conditions. Twelve days before the onset of the eruption, levofloxacin and vancomycin were started for presumed pneumonia. Cultures from the oropharynx revealed methicillin-resistant Staphylococcus aureus, and the smear was without neutrophils and contained numerous epithelial cells. No other medications had been started. (Source: Journal of the American Academy of Dermatology)

Aug 14, 2014 01:54AM

Optimizing the efficacy of targeted phototherapy by marking early vitiligo lesions after visualizing under a Wood's lamp

Targeted phototherapy can be an effective treatment for localized vitiligo. However, in patients with fairer skin types?especially Fitzpatrick skin phototypes I and II?some of the early lesions on the periphery may be missed. How can this be effectively overcome? (Source: Journal of the American Academy of Dermatology)

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