Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care

2262 Camino Ramon, San Ramon, CA 94583
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Patient Online Log in
(email staff to get your personal passcode)

* Patient Biopsy Results via LabCalls


MEDICAL DERMATOLOGY

Acne and Acne Scar

Excimer Laser for Psoriasis & Vitiligo

Keloid & Hypertrophic Scar Laser Therapy

Mohs Surgery for Skin Cancers

Nail Fungus GenesisPlus Laser Therapy

Photodynamic Therapy

Psoriasis & NBUVB Phototherapy

RadioTherapy Nonsurgical SRT-100 for Skin Cancer

Skin Allergy Patch Test

Sweating Disorder MiraDry for Hyperhidrosis

Wart Laser Therapy


COSMETIC DERMATOLOGY

Aesthetician Services
Microdermabrasion
 

Botox, Dysport & Xeomin

Cellulaze Cellulite Therapy

new! CoolSculpting

Facial Redness/Vein Laser Therapy

Fillers injection for Wrinkles

Fractional CO2 laser

new! Hair Transplant with Neograft

Laser Surgery Services
Acne/Pore reducing Laser
Collagen Stimulating Laser
Excimer Laser
Facial Veins laser
Hair Laser Removal
IPL Fotofacial
Melasma Laser
Nail Fungus Laser
Resurfacing Laser
Scar revision Laser
Tattoo Removal Lasers
VBeam Pulse Dye Laser
Wart Laser


Latisse

Leg Vein Laser Therapy & Asclera Sclerotherapy

Liposonix + Vaser Shape Nonsurgical Body Sculpting
 

Melasma and Pigmentation

Pore Size Reduction and Laser Rejuvenation

Sculptra Liquid Facelift

SideLaze Lift

Ulthera natural lift & skin tightening of face and neck


Related Websites
FaceUpLifting.com
iCellulaze.com
MoreHair4Me.com
SideLazeLift.com
SonixLipo.com


Email Dr. Ting Directly

925-328-0255

Name:
Phone:
Email:
Comments


* Review Dr. Ting's 717+ Q&A on RealSelf

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Tue, 21 Oct 2014 04:13:52 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Oct 20, 2014 08:10PM

Atrophie Blanche: Is It Associated with Venous Disease or Livedoid Vasculopathy?

No abstract available (Source: Advances in Skin and Wound Care)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 20, 2014 08:10PM

Meaningful Use:: Protect Electronic Health Information Through Security Risk Analysis

No abstract available (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

A Novel Hand-Shaped Suprathel Simplifies the Treatment of Partial-Thickness Burns

CONCLUSION:The use of the new Hand-Suprathel increases efficiency because of its convenient and faster application, as well as by reducing material waste. (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Atrophie Blanche: Is It Associated with Venous Disease or Livedoid Vasculopathy?

PURPOSE:The purpose of this learning activity is to provide information about the etiology and treatment of atrophie blanche. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able to:1. Discuss the pathophysiology of atrophie blanche.2. Explore treatment options for livedoid vasculopathy. (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Candida Species Isolation in Peristomal Skin in Patients with Abdominal Stomas and Correlation to Clinical Signs: A Descriptive Pilot Study

In this study, the authors report on Candida species prevalence, clinical correlation, and mycology. (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Braden Scale and Norton Scale Modified by INSALUD in an Acute Care Hospital: Validity and Cutoff Point

CONCLUSION:Both scales show good validity data. If the CP is raised: MI-Norton (CP 15): sensitivity: 77.36 (72.43?82.30), specificity 74.27 (72.94?75.61), PPV: 17.52 (15.42-19.62), NPV: 97.89 (97.38?98.41). The Braden scale with a CP of 17 presents sensitivity: 78.38 (73.52?83.24), specificity: 73.44 (72.09?74.79), PPV: 17.25 (15.19?19.31), NPV: 97.96 (97.45?98.47). These CPs improved the predictive capacity of both scales in the authors? hospital environment. (Source: Advances in Skin and Wound Care)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 20, 2014 08:10PM

Erratum

No abstract available (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Begin Preparing for 2015 Coding Changes: Use 4 New Modifiers Instead of Modifier 59

No abstract available (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Sensitivity and Specificity of a New Test for Thermographic Evaluation of the Foot in the Diagnosis of Diabetic Peripheral Polyneuropathy

CONCLUSIONS:This technique enabled the authors to quantify the degrees of colder or warmer temperature differences that participants with diabetes (with and without neuropathy) needed to be able to detect a difference, with acceptable sensitivity, specificity, and predictive values. (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

From the Editor?s Desk

No abstract available (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:10PM

Notable Achievements

No abstract available (Source: Advances in Skin and Wound Care)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 20, 2014 08:10PM

Heterotopic Bone Ossification: The Great Imitator: ?It?s Bone?

No abstract available (Source: Advances in Skin and Wound Care)

Oct 20, 2014 08:09PM

Effect of frequency on entrance and propagation pattern of high?frequency (radiofrequency) electrical currents in biologic tissues

ConclusionRadiofrequency currents have a tendency to move toward the center of the tissue. Frequency of current over the range of 0.4?3 MHz did not show any effect on this tendency. (Source: Skin Research and Technology)

Oct 20, 2014 06:22PM

Benefits of Psoriasis Drug Secukinumab Outweigh RisksBenefits of Psoriasis Drug Secukinumab Outweigh Risks

The benefits of Novartis AG's anti-inflammation drug outweighed the risks in using it to treat a type of psoriasis, staff reviewers at the U.S. Food and Drug Administration said. Reuters Health Information (Source: Medscape Dermatology Headlines)

Oct 20, 2014 06:06AM

Biological Therapies for Psoriasis: Effects on ReproductionBiological Therapies for Psoriasis: Effects on Reproduction

Are biological therapies for psoriasis safe to use in the pregnant patient? What impact might they have on paternal fertility and mutagenicity? The British Journal of Dermatology (Source: Medscape Today Headlines)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 19, 2014 04:00PM

The volume effect of lidocaine on thoracic epidural anesthesia in conscious Beagle dogs

Conclusions and clinical relevanceThe increase in volume of local anesthetic solution improved SB by resulting in more consistent bilateral dermatome blockade as well as an extended blockade. However, caution should be exerted, as higher volume injections of lidocaine caused side effects in all dogs. (Source: Veterinary Anaesthesia and Analgesia)

Oct 19, 2014 04:00PM

Human papillomavirus 66?associated subungual squamous cell carcinoma

(Source: The Journal of Dermatology)

Oct 19, 2014 04:00PM

Risk assessment for nickel contact allergy

Abstract Nickel is one of the most common allergens causing allergic contact dermatitis worldwide. The aim of the study was to evaluate the contributing factors to nickel contact allergy (NiCA) in Asians who have a unique culture and lifestyle. We randomly selected 324 previously patch?tested patients, 162 nickel patch test (PT)?positive patients and 162 nickel PT?negative patients. The patients were telephone interviewed for their lifestyle information. Most of the nickel PT?positive patients (93.2%) were female with a mean age of 38.9 ± 13.3 years compared with the other group of nickel PT?negative patients who had a smaller proportion of females (76.5%) with an older mean age of 44.1 ± 14.9 years (P = 0.001). Multivariate analysis was able to establish that the signi...

Oct 19, 2014 04:00PM

Severe exacerbation of psoriasis after intravenous immunoglobulin in patient with multiple sclerosis that started during biologic therapy

(Source: Journal of the European Academy of Dermatology and Venereology)

Oct 19, 2014 04:00PM

Cutaneous ulceration in dermatomyositis: Association with anti?melanoma differentiation?associated gene 5 antibodies and interstitial lung disease

Conclusion: We confirmed the strong association between anti?MDA5 antibodies and cutaneous ulcers, with the novel finding that the association of cutaneous ulcers with ILD depends upon the presence of anti?MDA5 antibodies. DM patients who display this cutaneous phenotype should undergo appropriate evaluation for ILD. © 2014 American College of Rheumatology. (Source: Arthritis Care and Research)

Oct 19, 2014 04:00PM

Skin DCs cluster for efficient T cell activation

Nature Immunology 15, 1004 (2014). doi:10.1038/ni.3012 Author: Scott N Mueller Clusters of dermal dendritic cells and T cells are required for efficient activation of T cells in skin following hapten sensitization via a process dependent on interleukin 1α (IL-1α) and the chemokine CXCL2 produced by macrophages. (Source: Nature Immunology)

Oct 19, 2014 04:00PM

Activated hypoxia?inducible factor?1? pathway modulates early events in stretch?induced skin neovascularization via stromal cell?derived factor?1 and vascular endothelial growth factor

ConclusionsThe HIF?1? pathway is quickly activated and modulates early events in stretch?induced skin neovascularization. The effect may be augmented through enhanced endothelial progenitor cells recruitment into the expanded skin. (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 19, 2014 04:00PM

Under?recognition of acral peeling skin syndrome: 59 new cases with 15 novel mutations

ConclusionsWe propose that APSS is under?reported and widely misdiagnosed as EBS?loc, with significant counselling implications as APSS is autosomal recessive while EBS?loc is dominant. We recommend screening for TGM5 mutations when EBS?loc is suspected but not confirmed by mutations in KRT5 or KRT14. Our report trebles the number of known TGM5 mutations. It provides further evidence that p.Gly113Cys is a founder mutation in the European population. This is consistent with the striking ethnic distribution of APSS in U.K., where the majority of patients are of nonconsanguineous white European origin, in contrast to the pattern of other recessive skin disorders. (Source: British Journal of Dermatology)

Oct 19, 2014 04:00PM

Daylight photodynamic therapy with methyl aminolevulinate cream as a convenient, similarly effective, nearly painless alternative to conventional photodynamic therapy in actinic keratosis treatment: a randomized controlled trial

ConclusionsDaylight?mediated PDT was not inferior in efficacy to Metvix c?PDT (mild AK response rate), better tolerated, nearly painless and more convenient for patients. (Source: British Journal of Dermatology)

Oct 19, 2014 04:00PM

Comparing treatment goals for psoriasis with treatment decisions in daily practice: results from a prospective cohort of patients with psoriasis treated with biologics: BioCAPTURE

ConclusionsPhysicians acted in accordance with treatment goals in the majority of patient visits. In the patient group not achieving these goals, physicians should have modified therapy according to treatment goals but continued the same therapeutic regimen in the majority of visits. Optimizing therapy and defining barriers in the latter group might increase treatment results in daily practice psoriasis care. (Source: British Journal of Dermatology)

Oct 19, 2014 04:00PM

Hidradenitis suppurativa fulminans: a clinically distinct phenotype?

(Source: British Journal of Dermatology)

Oct 19, 2014 04:00PM

Basal cell carcinomas in a tertiary referral centre: a systematic analysis

ConclusionsThis is the first study that analyses the frequency of complicated BCCs in a tertiary referral centre. There were 6·6% moderate (640 of 9652) and 0·6% (58 of 9652) severe cases. We found significantly more varying histological diagnoses and significant association with aggressive subtypes in moderate and severe cases. These patients might especially benefit from new therapeutic options. (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 18, 2014 04:00PM

Copulation in antiarch placoderms and the origin of gnathostome internal fertilization

Nature advance online publication 19 October 2014. doi:10.1038/nature13825 Authors: John A. Long, Elga Mark-Kurik, Zerina Johanson, Michael S. Y. Lee, Gavin C. Young, Zhu Min, Per E. Ahlberg, Michael Newman, Roger Jones, Jan den Blaauwen, Brian Choo & Kate Trinajstic Reproduction in jawed vertebrates (gnathostomes) involves either external or internal fertilization. It is commonly argued that internal fertilization can evolve from external, but not the reverse. Male copulatory claspers are present in certain placoderms, fossil jawed vertebrates retrieved as a paraphyletic segment of the gnathostome stem group in recent studies. This suggests that internal fertilization could be primitive for gnathostomes, but such a conclusion depends on demonstrating that copulation was not just a sp...

Oct 18, 2014 04:00PM

Motor function and survival following radiotherapy alone for metastatic epidural spinal cord compression in melanoma patients

Abstract The major goal of this study was the identification of predictors for motor function and survival after irradiation alone for metastatic epidural spinal cord compression (MESCC) from melanoma. Ten variables (age, gender, performance status, number of involved vertebrae, pre?radiotherapy ambulatory status, further bone metastases, visceral metastases, interval from melanoma diagnosis to MESCC, time developing motor deficits before radiotherapy, fractionation regimen) were investigated for post?radiotherapy motor function, ambulatory status and survival in 27 patients. On multivariate analysis, motor function was significantly associated with time developing motor deficits (P = 0.006). On univariate analysis, post?radiotherapy ambulatory rates were associated with pre?radi...

Oct 18, 2014 04:00PM

Acute generalized exanthematous pustulosis induced by oral prednisolone

(Source: The Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 18, 2014 04:00PM

First Japanese case of atypical progeroid syndrome/atypical Werner syndrome with heterozygous LMNA mutation

We report the first Japanese case of APS/AWS with a LMNA mutation (p.D300N). A 53?year?old Japanese man had a history of recurrent severe cardiovascular diseases as well as brain infarction and hemorrhages. Although our APS/AWS patient had overlapping features with Werner syndrome (WS), such as high?pitched voice, scleroderma, lipoatrophy and atherosclerosis, several cardinal features of WS, including short stature, premature graying/alopecia, cataract, bird?like face, flat feet, hyperkeratosis on the soles and diabetes mellitus, were absent. In immunofluorescence staining and electron microscopic analyses of the patient's cultured fibroblasts, abnormal nuclear morphology, an increase in small aggregation of heterochromatin and a decrease in interchromatin granules in nuclei of fib...

Oct 18, 2014 04:00PM

Japanese case of oculodentodigital dysplasia caused by a mutation in the GJA1 gene

(Source: The Journal of Dermatology)

Oct 18, 2014 04:00PM

Spontaneous regression of an epidermolysis bullosa nevus on the sole

We describe an older man with an EBN on the sole. Physical examination revealed irregularly pigmented band?like black macules on his right sole, suggestive of malignant melanoma. Dermoscopic examination showed a parallel furrow pattern with a monotonous area. The histopathological findings were consistent with a benign acquired nevus. Interestingly, the lesion regressed spontaneously within a year. To the best of our knowledge, this is the first reported case of EBN on the sole. Dermoscopy may be a useful addition to histopathological examination to ensure correct diagnosis of EBN. (Source: The Journal of Dermatology)

Oct 18, 2014 04:00PM

Bilateral linear nevus sebaceous: An unusual case

(Source: The Journal of Dermatology)

Oct 18, 2014 04:00PM

Achilles tendon ultrasonography may detect early features of psoriatic arthropathy in patients with cutaneous psoriasis

ConclusionsOur data confirm that ultrasonography is a sensitive technique which reveals enthesitis more frequently than clinical examination in patients affected by psoriasis. We suggest the use of ultrasonography of the Achilles tendon in early diagnosis of psoriatic arthropathy with the objective of preventing progression of the pathology. (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 18, 2014 04:00PM

Primary syphilis in HIV?negative patients is on the rise in Greece: epidemiological data for the period 2005?2012 from a tertiary referral centre in Athens, Greece

ConclusionPrimary syphilis in Greece is on the rise. ?he majority of our patients are Greek, despite immigrant influx. Men clearly outnumber women, representing more than 80% of the total number of patients. Furthermore, there seems to be a trend towards predominance of men having sex with men as the core group among male patients. (Source: Journal of the European Academy of Dermatology and Venereology)

Oct 17, 2014 04:00PM

Late-onset of immunodysregulation, polyendocrinopathy, enteropathy, x-linked syndrome (IPEX) with intractable diarrhea

We describe the case of a twelve-year old male affected by a very late-onset IPEX with intractable enteropathy, which markedly improved after starting Sirolimus as second-line treatment. This case suggests that IPEX should always be considered in the differential diagnosis of watery intractable diarrhea, despite its unusual onset. (Source: Italian Journal of Pediatrics)

Oct 17, 2014 08:20AM

Implant-Related Chronic Allergic Dermatitis May Promote Skin CancerImplant-Related Chronic Allergic Dermatitis May Promote Skin Cancer

Allergic contact dermatitis (ACD) associated with implantable medical devices can promote skin cancer development, according to a new case report and experimental findings. Reuters Health Information (Source: Medscape Medical News Headlines)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 17, 2014 08:03AM

Investigation of dyeing behavior of oxidative dye in fine structures of the human hair cuticle by nanoscale secondary ion mass spectrometry

ConclusionThe dyeing behavior of oxidative dyes in fine structures of hair cuticle was substantiated by NanoSIMS analysis using the improved hair cross?section preparation method. (Source: Skin Research and Technology)

Oct 16, 2014 04:00PM

Anti-SRP Antibody-positive Myopathy with Universal Alopecia and Multiple Vitiligo.

Authors: Tokuzumi M, Fujisawa T, Shu E, Kanoh H, Saigo C, Miyazaki T, Hamaguchi Y, Seishima M Abstract Abstract is missing (Short communication). PMID: 25325714 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)

Oct 16, 2014 04:00PM

Vegetating Inguinal and Perianal Lesions: A Quiz.

Authors: Salah LA Abstract Abstract is missing (Quiz). PMID: 25325567 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)

Oct 16, 2014 04:00PM

Fatal Thrombotic Thrombocytopenic Purpura in a Psoriasis Patient Treated with Ustekinumab and Methotrexate.

Authors: Philippe L, Badie J, Kattinger E, Faller JP, Deconinck E, Aubin F Abstract Abstract is missing (Short communication). PMID: 25325260 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)

Oct 16, 2014 04:00PM

Clinical Characterisation at Onset of Childhood Psoriasis - A Cross Sectional Study in Sweden.

Authors: Lysell J, Tessma M, Nikamo P, Wahlgren CF, Ståhle M Abstract Epidemiological data in childhood psoriasis are accumulating. However, reliable information captured at onset is lacking. In a cross sectional study we recruited 109 children <?16 years within 12 months of psoriasis onset and explored the clinical characteristics. Pre-pubertal children, especially boys, more often had inverse involvement (OR = 2.8, 95% CI = 1.1, 7.1, p???0.05). HLA-C*06 was positively associated with facial lesions (OR?=?3.8, 95% CI?=?1.5, 9.7, p?<?0.01) and guttate phenotype and was more common in pubertal children. A high PASI score was not associated with overweight or early age at onset, and gender did not influence disease onset. Psoriasis can be difficult to diagn...

Oct 16, 2014 11:39AM

Work begins on project to double Dermatology Clinic?s North Hillside office

Work has started on a project to double the space the Dermatology Clinic PA has at its North Hillside location. Larry Shackelford Construction has pulled a commercial building permit for an interior remodel at 851 N. Hillside. The permit is valued at $700,000. Jan Runa, the clinic's administrator, says construction started this week. She anticipates a four- to six-month completion time. The Dermatology Clinic is incorporating its existing space at 835 N. Hillside with an adjacent building to the? (Source: bizjournals.com Health Care:Physician Practices headlines)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 15, 2014 09:10PM

Improvement of efficacy in surgical management of facial basal cell carcinoma: an interdisciplinary pilot study in The Netherlands

Conclusions We found that in selected patients with high-risk facial BCCs, both specialists agreed that pre-operative consultation was not required. Once a standardized referral system has been implemented, its use may improve efficacy in the surgical treatment of high-risk facial BCC. Future research should be directed towards clinical controlled trials. Level of Evidence: Level III, risk/prognostic study. (Source: European Journal of Plastic Surgery)

Oct 15, 2014 09:00PM

DERMALONE (Nystatin, Neomycin Sulfate, Thiostrepton And Triamcinolone Acetonide) Ointment [Vedco]

Updated Date: Oct 16, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Oct 15, 2014 09:00PM

DERMA-VET (Nystatin, Neomycin Sulfate, Thiostrepton And Triamcinolone Acetonide) Ointment [Clipper Distribution Company LLC]

Updated Date: Oct 16, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Oct 15, 2014 07:17PM

Pharmacokinetics of metallic nanoparticles

Metallic nanoparticles (NPs) have been widely applied in the field of nanomedicine. A comprehensive understanding of their pharmacokinetics is crucial for proper risk assessment and safe biomedical applications. This review focuses on gold and silver (Ag) NPs, and briefly discusses iron oxide, titanium dioxide (TiO2), and zinc oxide NPs. Pharmacokinetics of metallic NPs depends on the particle type, size, surface charge, surface coating, protein binding, exposure route, dose, and species. Generally, blood half?life is shorter in rodents than in larger laboratory animals (e.g., rabbits or monkeys) and differs between intravenous and oral exposures. Oral, dermal, or inhalational absorption is low (?5%), but may increase with smaller sizes, negative charge, and appropriate coatings. Metal...

Oct 15, 2014 04:00PM

Obesity and atopy

This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 15, 2014 04:00PM

Primary Cutaneous B?Cell Lymphoblastic Lymphoma in Children. Report of Two Cases

We report two cases of primary cutaneous B?LBL that had initially been diagnosed as an infected dermoid cyst and lipoma, respectively, and referred for excision. The cases demonstrate the importance of biopsy and histopathologic examination of subcutaneous tumors to guide appropriate therapy. (Source: Pediatric Dermatology)

Oct 15, 2014 04:00PM

Distinctive clinical and dermoscopic features of BRAFp.V600K mutated melanomas

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Oct 15, 2014 04:00PM

Two Spanish cases of Atypical Melanosis of the Foot, an early stage of Acral Lentiginous Melanoma in situ

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 15, 2014 04:00PM

Trends in cutaneous malignant melanoma in Sweden 1997?2011: Thinner tumours and improved survival among men

ConclusionIn Sweden, the CMMs of men are detected earlier over time and this seems to be followed by an improved CMM?specific survival for men. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Oct 15, 2014 04:00PM

Preliminary one month stability screening of cosmetic multiple emulsions (W/O/W) prepared using cetyl dimethicone copolyol and Polysorbate 80

ConclusionAs a conclusion of this work, a stable multiple emulsion with 13.6% paraffin oil, 2.4% cetyl dimethicone copolyol and 0.8% polysorbate 80 can be formulated and can be further studied for any active ingredient for cosmetic purposes.This article is protected by copyright. All rights reserved. (Source: International Journal of Cosmetic Science)

Oct 15, 2014 04:00PM

CADASIL and CARASIL

Abstract CADASIL and CARASIL are hereditary small vessel diseases leading to vascular dementia. CADASIL commonly begins with migraine followed by minor strokes in mid?adulthood. Dominantly inherited CADASIL is caused by mutations (n?>?230) in NOTCH3 gene, which encodes Notch3 receptor expressed in vascular smooth muscle cells (VSMC). Notch3 extracellular domain (N3ECD) accumulates in arterial walls followed by VSMC degeneration and subsequent fibrosis and stenosis of arterioles, predominantly in cerebral white matter, where characteristic ischemic MRI changes and lacunar infarcts emerge. The likely pathogenesis of CADASIL is toxic gain of function related to mutation?induced unpaired cysteine in N3ECD. Definite diagnosis is made by molecular genetics but is also possible by elec...

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 15, 2014 04:00PM

Sacral perineural cyst mimicking inflammatory low back pain.

Authors: Ostojic P Abstract This case describes a 46-year-old woman with local pelvic and perineal pain, persisting for 2 years at presentation. The pain worsened during the night and morning and was alleviated during daily activities. Low back pain was associated with morning stiffness lasting longer than 2 h. Sometimes, she felt pain and numbness along her left S1 dermatome, without overt bladder or bowel incontinence. Lasegue's sign was negative. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were elevated (35 mm/h and 9.4, respectively) and Mennel's sign was present on both sides, indicating possible inflammation of the sacroiliac joints. However, radiographs of the lumbosacral spine and sacroiliac joints were normal. Magnetic resonance imaging (MRI) revea...

Oct 15, 2014 04:00PM

Psoriasis treatment and management - a systematic review of full economic evaluations.

This article is protected by copyright. All rights reserved. PMID: 25324036 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 15, 2014 04:00PM

Two Spanish cases of Atypical Melanosis of the Foot, an early stage of Acral Lentiginous Melanoma in situ.

This article is protected by copyright. All rights reserved. PMID: 25323966 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 15, 2014 04:00PM

Distinctive clinical and dermoscopic features of BRAFp.V600K mutated melanomas.

This article is protected by copyright. All rights reserved. PMID: 25323827 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 15, 2014 04:00PM

Trends in cutaneous malignant melanoma in Sweden 1997-2011: Thinner tumours and improved survival among men.

CONCLUSION: In Sweden, the CMMs of men are detected earlier over time and this seems to be followed by an improved CMM-specific survival for men. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men. This article is protected by copyright. All rights reserved. PMID: 25323770 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 14, 2014 11:00PM

Salamanders May Hold Clues to Human Scar Healing

Title: Salamanders May Hold Clues to Human Scar HealingCategory: Health NewsCreated: 10/14/2014 12:00:00 AMLast Editorial Review: 10/15/2014 12:00:00 AM (Source: MedicineNet Skin General)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 08:00PM

Ebola highlights disparity of disease burden in developed vs. developing countries

(University of Colorado Denver) A recent study in Journal of the American Academy of Dermatology shows Ebola and other skin disease rates are hundreds of times higher in developing than in developed countries. The study highlights the need for disease monitoring even when the global burden of disease remains low. (Source: EurekAlert! - Medicine and Health)

Oct 14, 2014 05:43PM

Oritavancin Shows Similar Safety as Vancomycin (CME/CE)

(MedPage Today) -- Once-weekly antibiotic effective for skin and soft tissue infections. (Source: MedPage Today Dermatology)

Oct 14, 2014 04:00PM

Esophageal cancer arising from esophageal mucous membrane pemphigoid

Abstract Uncommon bullous skin disorders including mucous membrane pemphigoid can sometimes involve the esophageal mucosa, but are not thought to be associated with esophageal neoplasia. A 57-year-old Caucasian woman with a history of refractory painful oral ulceration due to mucous membrane pemphigoid was found to have esophageal mucous membrane pemphigoid when her dysphagia and acid reflux symptoms were investigated. Repeated endoscopies with esophageal dilatation were performed for her recurrent stricturing esophageal mucous membrane pemphigoid. Five years after esophageal involvement was diagnosed, she developed squamous cell carcinoma of the oesophagus. Chronic inflammation of the squamous esophageal mucosal lining may explain the development of esophageal squamous cell carci...

Oct 14, 2014 04:00PM

A young man with expanding atrophic lesions

(Source: Clinical And Experimental Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

In vitro combination therapy using low dose clotrimazole and photodynamic therapy leads to enhanced killing of the dermatophyte Trichophyton rubrum

Conclusions: The combination of antifungal drug and RB-PDT represents an attractive alternative to the current antifungal therapies used to treat superficial fungal diseases. Our approach has the potential to reduce treatment times and drug dosages which can also reduce drug toxicity and improve patient compliance. (Source: BMC Microbiology)

Oct 14, 2014 04:00PM

Occlusive gloves and skin condition ? is there a problem? Results of a cross?sectional study in a semiconductor company

ConclusionsProlonged wearing of occlusive gloves with clean hands and without exposure to additional hazardous substances does not seem to negatively affect the skin.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Daylight photodynamic therapy for actinic keratoses: a randomized double?blinded nonsponsored prospective study comparing 5?aminolaevulinic acid nanoemulsion (BF?200) with methyl?5?aminolaevulinate

ConclusionsBF?200 ALA showed a trend towards improved efficacy results compared with MAL. Thicker lesions in both groups responded when treated repeatedly. Importantly, a thin 0·25?mm layer of the photosensitizer precursors was sufficient, which may lead to lower expense. (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

Itching is a significant problem and a mediator between disease severity and quality of life for patients with psoriasis: results from a randomized controlled trial

ConclusionsPruritus appears to be an important mediator of the association between improvements in disease severity and HRQOL in patients with moderate?to?severe psoriasis. (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Melatonin improves ultraviolet B?induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti

ConclusionUVB radiation induced oxidative stress in the skin culminating in an inflammatory response. The action of melatonin in protecting the skin from oxidative damage occurs in a receptor?independent manner by lowering the oxidative damage and inflammatory response. On the other hand, melatonin decreased the expression of NF??B and the circulating proinflammatory cytokine IL?6, suggesting an anti?inflammatory action in protecting the skin from UVB radiation. (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Clinical features and WNT10A mutations in seven unrelated cases of Schöpf?Schulz?Passarge syndrome

ConclusionsThis study reveals the range of ectodermal pathology in cases of SSPS that result from WNT10A mutations. Eyelid cysts provide a useful clinical clue to diagnosing SSPS which may be less rare than is currently appreciated. (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Human leucocyte antigen?Cw6 as a predictor for clinical response to ustekinumab, an interleukin?12/23 blocker, in Chinese patients with psoriasis: a retrospective analysis

ConclusionsThis pharmacogenetic study provides preliminary data indicating that positive HLA?Cw6 is associated with a good response to ustekinumab treatment in Chinese patients with psoriasis. (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Editor's Choice

(Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

Prospective registration of clinical trials published in the British Journal of Dermatology

(Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Personal reflections on 25 years of immunodermatology

(Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Fumarates for psoriasis: new insights into a small molecule prototype

ORIGINAL ARTICLE, p 732 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

A new perspective on histamine in atopic dermatitis

ORIGINAL ARTICLE, p 771 (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

Human papillomavirus and cutaneous squamous cell carcinoma: does ethnicity matter?

ORIGINAL ARTICLE, p 779 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Antithyroid hormone autoantibodies in vitiligo

ORIGINAL ARTICLE, p 786 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Peering under the skin: measuring melanoma depth with ultrasound and optical coherence tomography

ORIGINAL ARTICLE, p 799 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Laser energy: think of a number

ORIGINAL ARTICLE, p 806 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Malignancy behind chronic pruritus: the wolf in sheep's clothing?

ORIGINAL ARTICLE, p 839 (Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

Patterns of vascular birthmarks: questions and clues

ORIGINAL ARTICLE, p 868 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

The challenging task of screening and monitoring tuberculosis infection in candidates for biological therapies

ORIGINAL ARTICLE, p 884 (Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Erratum

(Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

News and Notices

(Source: British Journal of Dermatology)

Oct 14, 2014 04:00PM

Plain Language Summaries

(Source: British Journal of Dermatology)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 14, 2014 04:00PM

Phenotypic modulation of smooth muscle cells in lymphedema.

This article is protected by copyright. All rights reserved. PMID: 25319851 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 14, 2014 04:00PM

Occlusive gloves and skin condition - is there a problem? Results of a cross-sectional study in a semiconductor company.

CONCLUSIONS: Prolonged wearing of occlusive gloves with clean hands and without exposure to additional hazardous substances does not seem to negatively affect the skin. This article is protected by copyright. All rights reserved. PMID: 25319754 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Oct 14, 2014 04:00PM

Assessment of the Effect of Migration on Melanoma Incidence Trends in Australia Between 1982 and 2010 Among People Under 30.

Authors: Baade PD, Youlden DR, Youl P, Kimlin M, Sinclair C, Aitken J Abstract Abstract is missing (Letter to the Editor). PMID: 25315153 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)

Oct 14, 2014 07:36AM

Allergy To Orthopedic Metals Linked To Cancer

Orthopedic implants placed in locations just below the skin have been known to cause contact dermatitis in those allergic to certain alloys. Now research from Washington University in St. Louis (WUSL) has shown that these allergies can lead to rare cancers. (Source: Medical Design Online News)

Oct 14, 2014 05:59AM

Painful Blistering on the Dorsal Hands

By Wold, Lindsey; Lampel, Heather P. MD, MPH A 58-year-old man presented with an eight-month history of nail changes and painful blisters on the dorsal surface of his hands. He noticed these findings after working in his yard. He smokes three packs of cigarettes daily, and receives hemodialysis three times weekly for ESRD secondary to polycystic kidney disease. His medications included simvastatin, omeprazole, minoxidil, calcium, and a vitamin B complex.   The patient was well-appearing, had stable vitals, and wasn't in any acute distress. Skin examination revealed shallow, well-defined erosions, some with central crusting and adjacent 1-2 mm scattered white papules on the dorsum of his hands bilaterally, left greater than right. His fingers were tender to palpation, and his fingers ha...

Oct 14, 2014 04:05AM

Biologic Therapy With Topical Treatment in PsoriasisBiologic Therapy With Topical Treatment in Psoriasis

Does adjuvant topical therapy benefit patients undergoing biologic therapy for psoriasis? American Journal of Clinical Dermatology (Source: Medscape Today Headlines)

MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.

Oct 13, 2014 11:16PM

Combined Carbon Dioxide Laser with Photodynamic Therapy for Nodular and Superficial Basal Cell Carcinoma

ConclusionsCombined CO2 laser and PDT have equivalent cure rates to surgery for BCCs?notably of the nodular subtype?these modalities acting synergistically. This strategy provides cure often with scarless outcomes as illustrated. Laser with PDT is most appropriate for patients who value excellent cosmetic outcomes and where avoidance of an invasive procedure is an important factor. In addition, this modality comes into its own for specific groups of patients, such as those on Warfarin or those with diffuse or multiple lesions. (Source: Annals of Plastic Surgery)

Oct 13, 2014 11:16PM

Clinical Application of Cultured Epithelial Autografts on Acellular Dermal Matrices in the Treatment of Extended Burn Injuries

AbstractAchieving permanent replacement of skin in extensive full-thickness and deep partial-thickness burn injuries and chronic wounds remains one of the fundamental surgical problems. Presently, split-thickness skin grafts are still considered the best material for surgical repair of an excised burn wound. However, in burns that affect greater than 50% of total body surface area, the patient has insufficient areas of unaffected skin from which split-thickness skin grafts can be harvested. The use of cultured epithelial (or epidermal) autografts (CEAs) has achieved satisfactory results. But the take rate of CEAs is poor in full-thickness bed or in chronically infected area. Providing temporary cover with allograft skin, or a more permanent allodermis, may increase clinical take. This revi...

Oct 13, 2014 11:16PM

Book Review: Laser Dermatology, 2nd Edition

No abstract available (Source: Annals of Plastic Surgery)

Oct 13, 2014 04:00PM

Bench to bedside: mechanistic principles of targeting the RAF kinase in melanoma

Abstract Melanoma, in its advanced form, is an aggressive cancer with a poor prognosis. To date, no therapeutic modality has afforded a high likelihood of curative outcome, with the exception of early surgical resection in patients diagnosed with local disease. However, recent advances in our understanding of the molecular mechanisms and pathophysiology of melanoma have paved the way towards the development of targeted therapeutics. A central player in melanomagenesis is the RAF family of kinases. Key mechanistic details regarding the regulation of RAF kinases have now begun to emerge. Already, vemurafenib, a tailored kinase inhibitor of aberrant RAF function in melanoma, has led to clinical benefit. Despite vemurafenib's success, acquired resistance to the drug warrants the need for furth...

Oct 13, 2014 04:00PM

Rare skeletal abnormalities in Rothmund?Thomson syndrome: a case report

(Source: International Journal of Dermatology)