Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care
2262 Camino Ramon, San Ramon, CA 94583
500 Alfred Nobel Drive, Suite #185, Hercules, CA 94547
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Tue, 01 Sep 2015 09:27:28 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Sep 01, 2015 01:26AM

Flame Hair

Conclusion: The flame hair is a type of broken hair which can be seen in various hair loss disorders. It results from traumatic pulling of anagen hairs or from anagen arrest due to inflammation or drugs.Skin Appendage Disord 2015;1:105-109 (Source: Skin Appendage Disorders)

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Sep 01, 2015 12:22AM

Ustekinumab Found to Be Effective in Adolescents With PsoriasisUstekinumab Found to Be Effective in Adolescents With Psoriasis

Adolescents with moderate to severe psoriasis may respond to the human monoclonal antibody ustekinumab as well as adults, with no unexpected side effects, a new study found. Reuters Health Information (Source: Medscape Dermatology Headlines)

Aug 31, 2015 09:00PM

Restoration of Trigeminal Cutaneous Sensation with Cross-Face Sural Nerve Grafts: A Novel Approach to Facial Sensory Rehabilitation

Summary: Although treating facial palsy is considered debilitating for patients, trigeminal nerve palsy and sensory deficits of the face are overlooked components of disability. Complete anesthesia leaves patients susceptible to occult injury, and facial sensation is an important component of interaction and activities of daily living. Sensory reconstruction is well established in the restoration of hand sensation; however, only one previous report proposed a surgical strategy for sensory nerve reconstruction of the face with use of nerve transfers. Nerve transfers, when used alone, have limited application because of their restricted arc of rotation in the face; extending their arc by adding nerve grafts greatly expands their utility. The following cases demonstrate the early results afte...

Aug 31, 2015 06:35PM

Make the Diagnosis: Lesions, Fistulas and Shock

(MedPage Today) -- Case Findings: A 45 year-old male patient presented in septic shock. Multiple well-established ulcers and fistulas were present on his buttocks, thighs, and perineum. Immediate resuscitation and antibiotics were provided, as well as imaging of the lesions. What is your diagnosis? (Source: MedPage Today Dermatology)

Aug 31, 2015 04:00PM

Five?year risk of incident disease following a diagnosis of chronic rhinosinusitis

ConclusionThe risk of other diseases associated with CRS adds to the burden of an already highly burdensome condition, and suggests either that CRS promotes onset of other diseases or is an indicator of systemic disease processes. Different patterns of association with diseases by CRS phenotype may be due to CRSwNP sample size imitations or reflect a different pattern of disease onset by phenotype. These findings have implications for screening guidelines and care of CRS patients.This article is protected by copyright. All rights reserved. (Source: Allergy)

Aug 31, 2015 04:00PM

Diminution of Langerhans cells in keratitis, ichthyosis and deafness (KID) syndrome patient with recalcitrant cutaneous candidiasis

(Source: Journal of the European Academy of Dermatology and Venereology)

Aug 31, 2015 04:00PM

A Qualitative Comparison of Symptoms and Impact of Varying Stages of Basal Cell Carcinoma

Conclusions Patients with non-advanced or locally advanced and metastatic BCC experience disease-related symptoms that affect their HRQL, activities of daily living, emotional well-being, and social and/or leisure activities. Qualitative descriptions of patient experiences can help healthcare providers and caregivers better understand the impact of BCC from the patient perspective. Funding Eli Lilly and Company. (Source: Dermatology and Therapy)

Aug 31, 2015 02:01PM

4 DIY Home Manicure Must-Haves

by Holly Dawsey There's nothing quite like a fresh manicure to finish a look. Here, our picks for the top polish, base coat, top coat, and nail treatment. The Experts: Ilana Blitzer, Health beauty director; Paul Cucinello, celebrity hair stylist in Los Angeles and New York City; Francesca Fusco, MD, assistant clinical professor of dermatology at Mount Sinai Hospital in New York City; Suzy Gerstein, New York City celebrity makeup artist; Julie Kandalec, celebrity manicurist and creative director of Paintbox in New York City; Joanna Simkin, New York City celebrity makeup artist; Alexis Wolfer, founder of TheBeautyBean.com; Jessica Wu, MD, assistant clinical professor of dermatology at the University of Souther California School of Medicine in Los Angeles. Nail color Essie Cashmere Mattes (...

Aug 31, 2015 07:34AM

Breast Neoplasms with Dermal Analogue Differentiation (Mammary Cylindroma): Report of 3 Cases and a Proposal for a New Terminology

In this study, we present three cylindromatous breast tumours. These lesions were located within the breast, had ill-defined margins and were composed of nests containing a dual population of cytologically bland cells, surrounded at least partially by basement membrane-like material. The lack of cytological atypia and absence of mitoses led to the diagnosis of benign mammary cylindroma in 1 case. The expression of oestrogen receptor, focal absence of basement membrane material and the focal infiltrative nature together with patchy absence of peripheral basement membrane supported the diagnosis of malignancy in the other 2 cases. We discuss the morphological criteria, immunohistochemical profile and diagnostic pitfalls of these tumours. We also review the literature including previously rep...

Aug 31, 2015 02:29AM

Diet ISN'T causing your eczema and you CAN shower each day

Cutting out food groups, avoiding exercise and swimming will not cure eczema, according to Dr Adam Friedmann, a dermatologist from the Harley Street Dermatology Clinic. (Source: the Mail online | Health)

Aug 30, 2015 11:51PM

Impact of a Glycolic Acid-Containing pH 4 Water-in-Oil Emulsion on Skin pH

The skin pH is crucial for physiological skin functions. A decline in stratum corneum acidity, as observed in aged or diseased skin, may negatively affect physiological skin functions. Therefore, glycolic acid-containing water-in-oil (W/O) emulsions adjusted to pH 4 were investigated regarding their effect on normal or increased skin pH. A pH 4 W/O emulsion was applied on three areas with pathologically increased skin surface pH in diabetics (n = 10). Further, a 28-day half-side trial (n = 30) was performed to test the long-term efficacy and safety of a pH 4 W/O emulsion (n = 30). In summary, the application of a pH 4 W/O emulsion reduced the skin pH in healthy, elderly and diabetic subjects, which may improve epidermal barrier functions.Skin Pharmacol Physiol 2015;28:290-295 (Source: Skin...

Aug 30, 2015 08:01PM

AAP: Give peanut products to high-risk infants to cut allergy risk

Infants at high risk for peanut allergy should start a peanut-based diet by age 4-11 months, experts from the American Academy of Pediatrics and nine other medical groups advised in the September issue of the American Journal of Pediatrics. The consensus communication upends traditional views... (Source: Skin and Allergy News)

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Aug 30, 2015 04:00PM

Comparative study of nanosized cross-linked sodium-, linear sodium- and zinc-hyaluronate as potential ocular mucoadhesive drug delivery systems

Publication date: 15 October 2015 Source:International Journal of Pharmaceutics, Volume 494, Issue 1 Author(s): Gabriella Horvát, Mária Budai-Sz?cs, Szilvia Berkó, Piroska Szabó-Révész, Judit Soós, Andrea Facskó, Mónika Maroda, Michela Mori, Giuseppina Sandri, Maria Cristina Bonferoni, Carla Caramella, Erzsébet Csányi Hyaluronic acid (HA) and its derivatives play important roles in many fields of therapy, such as arthritis treatment, plastic surgery, dermatology, otology, ophthalmology, etc. With a view to increase the beneficial properties of HA in ocular drug delivery, many types of chemical structural modifications have been performed. In the course of our research work, we characterized nanosized cross-linked ? (CLNaHA), linear sodium hyaluronate (NaHA) and ...

Aug 30, 2015 04:00PM

Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology

by Joost F. M. Lensen, Johan van der Vlag, Elly M. M. Versteeg, Jack F. M. Wetzels, Lambert P. W. J. van den Heuvel, Jo H. M. Berden, Toin H. van Kuppevelt, Angelique L. W. M. M. Rops Dermatan sulfate (DS), also known as chondroitin sulfate (CS)-B, is a member of the linear polysaccharides called glycosaminoglycans (GAGs). The expression of CS/DS and DS proteoglycans is increased in several fibrotic renal diseases, including interstitial fibrosis, diabetic nephropathy, mesangial sclerosis and nephrosclerosis. Little, however, is known about structural alterations in DS in renal diseases. The aim of this study was to evaluate the renal expression of two different DS domains in renal transplant rejection and glomerular pathologies. DS expression was evaluated in normal renal tissue and in k...

Aug 30, 2015 04:00PM

Spectrométrie de masse : comment cette révolution technologique va impacter l?ensemble de la démarche diagnostique en parasitologie et mycologie

Publication date: September 2015 Source:Journal de Mycologie Médicale / Journal of Medical Mycology, Volume 25, Issue 3 Author(s): Renaud Piarroux La spectrométrie de masse matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF), a maintenant supplanté les méthodes traditionnelles d?identification des bactéries dans les laboratoires de biologie médicale. En mycologie médicale, l?expertise du mycologue à la paillasse semble plus difficile à remettre en cause, en particulier pour les moisissures et les dermatophytes. À Marseille cependant, la spectrométrie de masse MALDI-TOF est maintenant à la base de notre processus d?identification de l?ensemble des colonies fongiques, moisissures, levures et dermatophytes inclus. Un recul de trois années et plus...

Aug 30, 2015 04:00PM

Caractérisation microbiologique de 3193 logements français des enfants de la cohorte ELFE

Conclusion Les cohortes de naissance sont essentielles pour comprendre l?apparition des maladies respiratoires au cours de la vie. Certains enfants de la cohorte ELFE développeront inévitablement de l?asthme entre 4?7ans. Nous pourrons alors comparer la survenue de l?asthme aux types de profils microbiens des logements qu?ils occupaient à la naissance. (Source: Journal of Medical Mycology)

Aug 30, 2015 04:00PM

Épidémiologie des dermatophyties zoophiles sur une période de 5ans à l?hôpital militaire de Rabat

Conclusion Les dermatophyties sont des mycoses superficielles fréquentes de la peau et des phanères, causées par des champignons microscopiques filamenteux. Les dermatophytes zoophiles sont pourvoyeuses de teignes du cuir chevelu et de la barbe, des folliculites et des épidermophyties de la peau glabre ; l?enfant et le jeune adolescent sont les plus touchés. Dans ce sens, le laboratoire de mycologie joue un rôle primordial dans la prise en charge de ces patients. (Source: Journal of Medical Mycology)

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Aug 30, 2015 04:00PM

Hidradenitis suppurativa?acne inversa: a relevant dermatosis in paediatric patients

(Source: British Journal of Dermatology)

Aug 30, 2015 04:00PM

Eccrine poroma: the great dermoscopic imitator

(Source: Journal of the European Academy of Dermatology and Venereology)

Aug 30, 2015 04:00PM

Papillary intralymphatic angioendothelioma (PILA), also referred to as Dabska tumour, in an 83?year?old woman

(Source: Journal of the European Academy of Dermatology and Venereology)

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Aug 30, 2015 04:00PM

Fully regressive lesions: how dermoscopy can help us?

(Source: Journal of the European Academy of Dermatology and Venereology)

Aug 30, 2015 04:00PM

Pneumocephalus as a fatal complication of scalp angiosarcoma

(Source: Journal of the European Academy of Dermatology and Venereology)

Aug 30, 2015 04:00PM

Magnet hanging on the skin ? An easy method to detect occult metallic cutaneous foreign body

(Source: Journal of the European Academy of Dermatology and Venereology)

Aug 30, 2015 04:00PM

Pictorial representation of illness and self measure (PRISM): an effective tool to assess the burden of psoriasis

ConclusionPRISM is a highly reliable tool and new approach to assess perceived burden of patients with psoriasis. It is easy to use and we recommend the application as an additional outcome measure in clinical trial settings. (Source: Journal of the European Academy of Dermatology and Venereology)

Aug 30, 2015 04:00PM

Cutaneous and breast Langerhans cell sarcoma

(Source: Journal of the European Academy of Dermatology and Venereology)

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Aug 29, 2015 10:12PM

High frequency of contact allergy to implant and bone cement components, in particular gentamicin, in cemented arthroplasty with complications: usefulness of late patch test reading

ConclusionLate reading is useful for patch tests with metals and bone cement components. With only D2/D3 readings, 32 reactions to nickel, cobalt, chromium and bone cement components would have been missed. This underlines the utility of late reading in general and in complicated cemented arthroplasty patients, given the unexpectedly high number of gentamicin reactions. (Source: Contact Dermatitis)

Aug 29, 2015 07:56PM

Clinical Management and Use of Health Care Resources in the Treatment of Nasal Polyposis in Spanish Allergy Centers: The POLAR Study.

CONCLUSIONS: NP is a chronic inflammatory disease that generates considerable use of health care resources. The close association with atopy, asthma, and NSAID hypersensitivity highlights the usefulness of an allergy workup in all patients with NP. Analysis of the clinical management of NP by allergists in Spain revealed a high degree of compliance with EPOS diagnostic and therapeutic recommendations. PMID: 26310042 [PubMed - in process] (Source: Journal of Investigational Allergology and Clinical Immunology)

Aug 29, 2015 04:00PM

Biological therapy induces expression changes in Notch pathway in psoriasis

This study aimed to determine mRNA expression levels by real-time RT-PCR, and protein expression levels, analysed by Western blot and immunohistochemistry, of some components of the Notch pathway, such as NOTCH1, NOTCH2, JAGGED1, and HES1 after biological treatments in psoriatic patients. mRNA and protein levels of NOTCH1, NOTCH2, JAGGED1 and HES1 were upregulated in skin samples from untreated psoriatic patients compared with normal controls. Biological therapy showed to downregulate differently the protein expression levels of the molecules under study. Our study suggests that Notch pathway components might be a potential therapeutic target against psoriasis. (Source: Archives of Dermatological Research)

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Aug 29, 2015 04:00PM

Antiviral activity of some plant oils against herpes simplex virus type 1 in Vero cell culture

Conclusion It can be concluded that the oils studied in this research have significant inhibitory effect on HSV-1 and thus they could be used as an anti-HSV-1 agent in the context of herbal mouth wash. (Source: Journal of Acute Medicine)

Aug 29, 2015 04:00PM

Real-time PCR: A rapid and sensitive method for diagnosis of dermatophyte induced onychomycosis, a comparative study

Conclusion: Real-time PCR followed by melting-point analysis, gives a diagnostic tool that has a higher sensitivity (93.3%) and is faster than nested PCR (73.3%) and other conventional methods. (Source: Alexandria Journal of Medicine)

Aug 29, 2015 04:00PM

Merkel cell carcinoma in Scotland 2000?10

(Source: British Journal of Dermatology)

Aug 29, 2015 04:00PM

Evaluation of anti?acne properties of phloretin in vitro and in vivo

ConclusionsThis study revealed that phloretin inhibits the growth of P. acnes, P. granulosum, and S. epidermidis. In addition, we demonstrated that phloretin attenuates COX?2 and PGE2 expression during the P. acnes?induced upregulation of inflammatory signalling. Clinical studies further suggested that treatment with formulations containing phloretin confers anti?acne benefits. Based on these results, we suggest that phloretin may be introduced as a possible acne?mitigating agent. Résumé ObjectifLa présente étude visait à étudier les propriétés anti?acné de phlorétine in vitro et in vivo. MéthodesL'activité anti?microbienne contre Propionibacterium acnes (P. acnes), Propionibacterium granulosum (P. granulosum), Staphylococcus epidermidis (S. epidermidis) a...

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Aug 29, 2015 12:38PM

Predictors of smoking reduction outcomes in a sample of 287 patients with schizophrenia spectrum disorders.

Authors: Wu BJ, Lan TH Abstract Many studies have investigated whether a type of antipsychotics or type of adjuvant is associated with smoking reduction in patients with schizophrenia. However, there has been no study exploring a comprehensive range of factors related to smoking reduction in schizophrenia patients. We analyzed a dataset of 287 smoking patients with schizophrenia who participated in an 8-week open-label study with high- (n = 90) or low-dose nicotine dermal patches (n = 132) or bupropion (n = 65). A logistic regression model and a linear mixed model were used to explore factors associated with the outcomes of smoking cessation and reduction, i.e., the number of cigarettes smoked and the level of nicotine dependence. The total cessation rate was 6.3 % (18/287)....

Aug 29, 2015 03:46AM

Preserved cutaneous silent period in cervical root avulsion.

Conclusion In brachial plexopathy even with plurisegmental root avulsion, the cutaneous SP was mostly preserved. This method cannot be recommended as a reliable test for diagnosis of single root avulsion; however, it can provide a quick physiological confirmation of functional afferent A-delta fibers through damaged roots and/or trunks. The clinicians may add this test to the diagnosis of spinal cord dysfunction. PMID: 26312387 [PubMed - as supplied by publisher] (Source: Journal of Spinal Cord Medicine)

Aug 28, 2015 11:00PM

Dermatophytosis: a 16-year retrospective study in a metropolitan area in southern Brazil

Conclusion: Monitoring of the evolution of dermatophytosis tracks changes in prevalence over the years and may assist practical measures for the public health control of this disease. (Source: The Journal of Infection in Developing Countries)

Aug 28, 2015 07:58PM

Isotretinoin conundrum: a randomized, openlabel, crossover study in Mexico to evaluate the bioavailability and bioequivalence of three pharmaceutical preparations of isotretinoin in healthy participants.

CONCLUSION: Oratane and Australian-sourced Roaccutane could be considered bioequivalent, but neither formulation was found to be bioequivalent to Mexican-sourced Roaccutan. PMID: 26308169 [PubMed - as supplied by publisher] (Source: International Journal of Clinical Pharmacology and Therapeutics)

Aug 28, 2015 07:32PM

Two Cases of Occupational Contact Urticaria Caused by Percutaneous Sensitization to Parvalbumin

Conclusion: The patients' histories and findings indicate the possibility of percutaneous sensitization through occupational exposure to parvalbumin, leading to food allergy.Case Rep Dermatol 2015;7:227-232 (Source: Case Reports in Dermatology)

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Aug 28, 2015 07:28PM

Lichen planus and lichenoid reactions as a systemic disease

Lichen planus (LP) is a chronic disease that involves the skin, scalp, mucous membranes, and nails. The etiology of LP is still unknown; however, some external and internal factors (eg. drugs, stress, hepatitis C virus) have been suggested to trigger the disease. Many studies have investigated an immunologic pathogenesis that is probably related to T-cell autoimmunity with the keratinocyte as the target cell. Altered self-antigens on the surface of basal keratinocytes modified by viruses or by drugs are believed to be the targets of the T-cell response. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Seronegative reactive spondyloarthritis and the skin

Spondyloarthritidies represent a group of conditions affecting the axial and peripheral muscoloskeletal apparatus and are often associated with psoriasis, infections, and inflammatory bowel diseases. Other diseases included in this category are psoriatic arthritis, ankylosing spondylitis, and enteropathic arthritis. Reactive arthritis is an elusive spondyloarthritis, commonly occurring 1 to 3 weeks after a digestive or a genitourinary tract infection, in which microorganisms do not infect the joint directly. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Pyoderma gangrenosum?a systemic disease?

Pyoderma gangrenosum (PG) is an orphan disease. It belongs to the group of neutrophilic dermatoses. Four major subtypes and several rare manifestations illustrate the great variety of clinical presentations and clinical course. PG is potentially life threatening and associated with a number of internal diseases including chronic inflammatory bowel disease, hematologic disorders, and malignancies. PG itself shows extracutaneous manifestations. These findings are in favor of PG as a systemic disease. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Cutaneous manifestations of systemic autoinflammatory disorders

Rare systemic autoinflammatory diseases (sAIDs) are driven by cytokine-mediated uncontrolled inflammation that results from activation of innate immune pathways. sAIDs present with recurrent fever episodes, fatigue, musculoskeletal symptoms, gastrointestinal, neurologic, and skin manifestations. They include hereditary monogenic and acquired multifactorial disorders, show a significant morbidity and usually persist for life. Due to the limited awareness of sAIDs, they are often associated with a considerable delay in diagnosis. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Lyme disease/borreliosis as a systemic disease

Lyme disease/borreliosis (LD) is a well-known arthropod-transmitted entity in the northern hemisphere. The incidence of LD is reportedly rising throughout the world, although better diagnostic facilities may be contributory. The disease distribution is expanding in Europe, with its presence being now documented at higher altitudes and latitudes. Borrelia burgdorferi sensu lato is the most important genospecies leading to LD, although newer ones continue to be discovered. The variations in clinical spectrum with genospecies involved are an interesting feature. (Source: Clinics in Dermatology)

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Aug 28, 2015 07:28PM

Systemic drug reactions with skin involvement: Stevens-Johnson syndrome, toxic epidermal necrolysis, and DRESS

Skin is often affected in adverse drug reactions. Although the majority of cutaneous adverse drug reactions are benign and self-limiting, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS), affecting multiple organs and systems, are potentially fatal. Many organs can be affected, including the mucosal membranes, gastrointestinal tract, liver, lungs, kidneys, and eyes. We discuss the causes, pathophysiologic aspects, and main clinical features of SJS, TEN, and DRESS as systemic diseases with skin involvement. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Is herpes simplex a systemic disease?

Orofacial herpes simplex virus infections are usually caused by herpes simplex virus 1 (HSV-1), and HSV-2 infections have been accepted as a sexually transmitted disease. HSV establishes a latent infection in the dorsal root ganglia of the host and remains there for the rest of life. HSV affects mainly skin and genitalia, although in immunocompromised patients it may cause local infection with vast skin involvement, chronic herpetic ulcers, or widespread mucous membrane damage, as well as systemic infections localized in the central and peripheral nervous systems, gastrointestinal tract, and ocular system. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Systemic involvement in mycosis fungoides

Mycosis fungoides (MF) represents almost 50% of all primary cutaneous lymphomas and more than 70% of cutaneous T-cell lymphomas (CTCL). Arising from preferentially skin-homing lymphocytes with genetic instability, MF evolves through stages (IA-IVB), producing inconspicuous inflammatory features in the beginning and finally resulting in a proliferation of cytomorphologic, phenotypic, and genotypic abnormal tumor cells. Over the past 200 years, there has been much confusion in the classification of lymphomas due to semantic disagreements (MF, CTCL, parapsoriasis, lymphosarcoma, reticulum cell sarcoma, and many other terms), lack of diagnostic standard criteria, and new molecular diagnostic methods. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Acne - a potential skin marker of internal disease

Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in adult women. Hyperandrogenism is the crux of the pathogenesis of both acne and hirsutism, the most frequent clinical presentations of the syndrome. The chronic anovulation that may occur, often but not always associated with enlarged cystic ovaries, has long been recognized as an important feature of PCOS.In recent years major changes have occurred with regard to PCOS:Although management of the common cutaneous manifestations, mainly acne, hirsutism, alopecia, and acanthosis nigricans, remains strictly within the realm of daily dermatologic practice, the pendulum is shifting toward greater awareness of the longer-term systemic implications of PCOS, with emphasis on the unique opportunity and privileged position of...

Aug 28, 2015 07:28PM

Systemic involvement in localized scleroderma/morphea

Localized scleroderma (LoSc), also known as morphea, is a rare fibrosing disorder of the skin and underlying tissues. Sclerosis is mainly limited to the skin, but subcutaneous tissue, fascia, and underlying muscles and bone may also be involved. In some cases, systemic manifestation with visceral abnormalities may occur. Several publications have focused on significant aspects of LoSc: genetics, immunity, epidemiology, scoring systems, and unification of classifications. Clinical studies featuring large cohorts with the disease published by various international study groups have been of great value in furthering the diagnostic and therapeutic management of LoSc. (Source: Clinics in Dermatology)

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Aug 28, 2015 07:28PM

The skin as a target organ in multisystemic diseases II

Progress in medical science has given a new reading to the claim that the skin could be a mirror of the pathological changes found in the internal organs. The concept that we previously promoted is furthered in this issue; namely that the greatest part of skin diseases are systemic ones.In this issue we focus on another group of diseases with systemic involvement and skin manifestations. We review such inflammatory conditions as lichen planus, autoinflammatory syndromes, and pyoderma gangrenosum focusing on their systemic involvement. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

(History of Mexican Dermatology)

This book is handsome?a foot high with a sober navy blue hard cover featuring a 1905 photograph of Mexico?s General Hospital. The one-volume work is printed on high-quality thick, low-reflectance glossy paper. The print is extremely neat and easy to read. The many pictures (not consecutively numbered) are all in black and white, which to me seems somehow appropriate to a historical treatise. Unfortunately, the thick, heavy pages are not well bound, so they tend to come loose. The 43 co-authors are all leaders in contemporary Mexican dermatology. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

?Work itself is a pleasure.? 200th anniversary of the birth of James Paget (1814-1899)

The year 2014 marked the two hundredth anniversary of the birth of James Paget (1814-1899), one of the most famous of English surgeons. Paget was considered an excellent clinician in his own lifetime and was careful in his scientific observations. Rarely did he ever work fewer than 16 hours a day. Not only did he contribute to the development of surgery, but he also made important dermatologic observations. In addition to describing cases of bone deformations, now called Paget?s disease of the bone, he also described chronic ulceration of the nipple associated with breast cancer, additionally known as Paget?s disease. (Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Table of Contents

(Source: Clinics in Dermatology)

Aug 28, 2015 07:28PM

Editorial Board

(Source: Clinics in Dermatology)

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Aug 28, 2015 07:25PM

ST2 receptor invalidation maintains wound inflammation, delays healing and increases fibrosis

This article is protected by copyright. All rights reserved. (Source: Experimental Dermatology)

Aug 28, 2015 06:35PM

Spironolactone: The 'Other' Hormonal Acne Therapy

(MedPage Today) -- Expert: drug is effective and its safety issues can be managed (Source: MedPage Today Dermatology)

Aug 28, 2015 04:09PM

Biomarkers for atopic dermatitis: a systematic review and meta-analysis

Purpose of review: A large number of studies investigating the correlation between severity of atopic dermatitis and various biomarkers have been published over the past decades. The aim of this review was to identify, evaluate and synthesize the evidence examining the correlation of biomarkers with disease severity in atopic dermatitis patients, something that has not been performed previously. Recent findings: Three electronic databases were systematically searched and relevant studies were selected for inclusion. A total of 222 articles, reporting on 115 different biomarkers in 30?063 patients, were critically appraised. Studies were divided into two main groups. The first group consisted of longitudinal randomized controlled trials and cohort studies, which reported measurements at m...

Aug 28, 2015 04:09PM

Current novel approaches in systemic therapy of atopic dermatitis: specific inhibition of cutaneous Th2 polarized inflammation and itch

Purpose of review: This present review gives an overview on different approaches on systemic treatment of atopic dermatitis with a focus on molecules that are presently investigated as defined target structures in clinical studies with patients with atopic dermatitis. Recent findings: Available systemic drugs for the treatment of atopic dermatitis are limited. There is a high need for the development of new treatment regimen. Current studies address novel biologicals or small molecules for the treatment of atopic dermatitis. In particular, interventions in the T-helper 2 cell (Th2) allergic inflammation are promising. Dupilumab, a humanized monoclonal antibody to the interteukin-4R is the first antibody (i.e. ?biological?) with published efficacy shown in controlled prospective studies...

Aug 28, 2015 04:09PM

From genetics to treatment of eosinophilic esophagitis

Purpose of review: Eosinophilic Esophagitis (EoE) is an emerging chronic atopic disease. Recent advances in understanding its genetic and molecular biology pathogenesis may lead to a better management of the disease Recent findings: EoE is an atopic disease. Most of the patients affected by EoE have other atopic diseases such as allergic rhinitis, asthma, IgE-mediated food allergies and/or atopic dermatitis. The local inflammation is a T helper type 2 (Th2) flogosis, which most likely is driven by a mixed IgE and n-IgE-mediated reaction to food and/or environmental allergens. Epidemiological studies show that EoE is an atopic disease with a strong genetic component. Genetic studies have shown that EoE is associated with single nucleotide polymorphism on genes, which are released by the epi...

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Aug 28, 2015 04:06PM

Evaluation of the Role of IgE Responses to Der p 1 and Der p 2 in Chinese House Dust Mite-Allergic Patients

Conclusions: In China, Der p 1 and Der p 2 are the dominant allergens in patients with HDM allergy. The relative importance of Der p 1 and Der p 2 changes with age, in favor of Der p 2. Overall, sIgE titers were positively associated with the number of organs affected.Int Arch Allergy Immunol 2015;167:203-210 (Source: International Archives of Allergy and Immunology)

Aug 28, 2015 04:00PM

Development of a topical ointment of betamethasone dipropionate loaded nanostructured lipid carrier

Publication date: Available online 28 August 2015 Source:Asian Journal of Pharmaceutical Sciences Author(s): Xin Kong, Yuan Zhao, Peng Quan, Liang Fang The purpose of this study was to design an innovative topical ointment containing betamethasone dipropionate loaded nanostructured lipid carrier (BD-NLC) for the treatment of atopic dermatitis (AD). BD-loaded NLC was produced with precirol ATO 5 and oleic oil (OA) by melt emulsification method. Effects of surfactant concentration, amount of solid lipid and liquid lipid on skin retention and skin penetration were investigated by in vitro percutaneous permeation experiment. The optimized BD-NLC showed a homogeneous particle size of 169.1 nm (with PI=0.195), negatively charged surface (?23.4 mV) and high encapsulation efficiency (85%)....

Aug 28, 2015 04:00PM

Diet-induced hypercholesterolemia imparts structure-function changes to erythrocyte chondroitin sulphate/dermatan sulphate

This study was carried out to determine whether diet-induced hypercholesterolemia had any effect on erythrocyte CS/DS and impacted cytoadherence to ECM components. Unlike in diabetes, diet-induced hypercholesterolemia did not show quantitative changes in erythrocyte CS/DS but showed difference in proportion of un-sulphated and 4-O-sulphated disaccharides. Erythrocytes from hypercholesterolemic rats showed increased adhesion to ECM components which was abrogated to various extents when subjected to chondroitinase ABC digestion. However, isolated CS/DS chains showed a different pattern of binding to ECM components indicating that orientation of CS/DS chains could be playing a role in binding. (Source: Journal of Biochemistry)

Aug 28, 2015 04:00PM

ABCB5 Identifies Immunoregulatory Dermal Cells

Publication date: Available online 28 August 2015 Source:Cell Reports Author(s): Tobias Schatton, Jun Yang, Sonja Kleffel, Mayuko Uehara, Steven R. Barthel, Christoph Schlapbach, Qian Zhan, Stephen Dudeney, Hansgeorg Mueller, Nayoung Lee, Juliane C. de Vries, Barbara Meier, Seppe Vander Beken, Mark A. Kluth, Christoph Ganss, Arlene H. Sharpe, Ana Maria Waaga-Gasser, Mohamed H. Sayegh, Reza Abdi, Karin Scharffetter-Kochanek, George F. Murphy, Thomas S. Kupper, Natasha Y. Frank, Markus H. Frank Cell-based strategies represent a new frontier in the treatment of immune-mediated disorders. However, the paucity of markers for isolation of molecularly defined immunomodulatory cell populations poses a barrier to this field. Here, we show that ATP-binding cass...

Aug 28, 2015 04:00PM

Association between childhood eczema and headaches: An analysis of 19 US population-based studies

Atopic dermatitis (or eczema) is a chronic inflammatory disorder associated with sleep disturbances and quality-of-life impairment. Sleep disturbances have been shown to cause headaches in childhood. However, an association between eczema and headaches is not well established. (Source: Journal of Allergy and Clinical Immunology)

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Aug 28, 2015 04:00PM

Successful treatment of bilateral multiple lymph node metastases in extramammary Paget's disease with surgery and sequential chemotherapy of S?1 and docetaxel

(Source: The Journal of Dermatology)

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Aug 28, 2015 04:00PM

Real-time vascular imaging and photodynamic therapy efficacy with micelle-nanocarrier facilitate the delivery of chlorin e6 to the microenvironment of melanoma

Cancer cells in primary tumors are surrounded by a complex microenvironment comprised of numerous types of cells, including endothelial cells of the blood and lymphatic circulation, stromal fibroblasts and a variety of bone marrow-derived cells such as macrophages and endothelial cell progenitors [1]. Endothelial cells are indispensible for angiogenesis, the process whereby new vasculature develops, which plays a pivotal role in tumor growth, invasion and metastasis [2,3]. Hence the tumor vasculature is an attractive target for cancer therapy. (Source: Journal of Dermatological Science)

Aug 28, 2015 04:00PM

Development of a Patient-Reported Outcome Questionnaire for Use in Adults with Moderate-to-Severe Plaque Psoriasis: the Psoriasis Symptoms and Signs Diary

Conclusion The PSSD, developed according to the Food and Drug Administration (FDA) PRO Guidance, assesses severity of symptoms and signs commonly associated with plaque PsO. Its measurement properties are currently being evaluated. (Source: Journal of Dermatology and Dermatologic Surgery)

Aug 28, 2015 04:00PM

Diffuse intramuscular lipoma responsible of monomelic hypertrophy

Conclusion This case report described an adult female patient with an unusually intramuscular lipoma where magnetic resonance imaging was playing an important role in the diagnostic. Indeed the intramuscular is a benign fatty tumor with characteristic appearance on MRI. Its management should be considered in multidisciplinary collaboration. (Source: Journal of Dermatology and Dermatologic Surgery)

Aug 28, 2015 12:17PM

CMS: We?re ready to accept and process ICD-10 claims

The Centers for Medicare and Medicaid Services says it completed its final Medicare fee-for-service end-to-end testing of ICD-10 with positive results. ?This final end-to-end testing [that occurred July 20-24] demonstrated that CMS systems are ready to accept and process ICD-10 claims,? the... (Source: Skin and Allergy News)

Aug 28, 2015 08:50AM

Differentiating chondroitin sulfate glycosaminoglycans using collision-induced dissociation; uronic acid cross-ring diagnostic fragments in a single stage of tandem mass spectrometry.

Authors: Kailemia MJ, Patel AB, Johnson DT, Li L, Linhardt RJ, Amster IJ Abstract The stereochemistry of the hexuronic acid residues of the structure of glycosaminoglycans (GAGs) is a key feature that affects their interactions with proteins and other biological functions. Electron based tandem mass spectrometry methods, in particular electron detachment dissociation (EDD), have been able to distinguish glucuronic acid (GlcA) from iduronic acid (IdoA) residues in some heparan sulfate tetrasaccharides by producing epimer-specific fragments. Similarly, the relative abundance of glycosidic fragment ions produced by collision-induced dissociation (CID) or EDD has been shown to correlate with the type of hexuronic acid present in chondroitin sulfate GAGs. The present work examines the e...

Aug 28, 2015 07:06AM

ACOs generate savings, but few get bonuses

Accountable care organizations (ACOs) accounted for savings of more than $411 million in 2014, according to the Centers for Medicare & Medicaid Services. However, of the 20 Pioneer ACO programs and the 333 ACOs participating in the Medicare shared savings program, 97 qualified for shared... (Source: Skin and Allergy News)

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Aug 27, 2015 10:09PM

Hand Dermatitis: Clinical Features, Prevention and TreatmentHand Dermatitis: Clinical Features, Prevention and Treatment

Hand dermatitis is a common problem, especially prevalent in occupations such as hairdressers, cleaners, healthcare workers, and others. Read about its etiology and current therapies in this review. American Journal of Clinical Dermatology (Source: Medscape Today Headlines)

Aug 27, 2015 09:00PM

DERMACHLOR FLUSH PLUS (Lidocaine Hydrochloride, Chlorhexidine) Liquid [Henri Schein Animal Health]

Updated Date: Aug 28, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Aug 27, 2015 04:00PM

Fibulin-4 Knock-in Mouse Model for Recessive Cutis Laxa 1B [Molecular Bases of Disease]

Fibulin-4 is an extracellular matrix protein essential for elastic fiber formation. Frameshift and missense mutations in the fibulin-4 gene (EFEMP2/FBLN4) cause autosomal recessive cutis laxa (ARCL) 1B, characterized by loose skin, aortic aneurysm, arterial tortuosity, lung emphysema, and skeletal abnormalities. Homozygous missense mutations in FBLN4 are a prevalent cause of ARCL 1B. Here we generated a knock-in mouse strain bearing a recurrent fibulin-4 E57K homozygous missense mutation. The mutant mice survived into adulthood and displayed abnormalities in multiple organ systems, including loose skin, bent forelimb, aortic aneurysm, tortuous artery, and pulmonary emphysema. Biochemical studies of dermal fibroblasts showed that fibulin-4 E57K mutant protein was produced but was prone to d...

Aug 27, 2015 04:00PM

Practical Management of CD30 Lymphoproliferative Disorders

This article discusses various treatment choices for each of the CD30+ disorders and offers practical pearls to aid in choosing an appropriate regimen. (Source: Dermatologic Clinics)

Aug 27, 2015 04:00PM

Histone Deacetylase Inhibitors for Cutaneous T-Cell Lymphoma

Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin?s T-cell lymphomas that present as skin lesions. Mycosis fungoides with large cell transformation has a 5-year overall survival of 32% with involved skin and 7% with extracutaneous involvement. Failure to cure MF with large cell transformation and peripheral T-cell lymphoma has resulted in a search for novel targeted agents including antibodies and gene modulators. Histone deacetylase inhibitors are small molecules that seem to be particularly active for T-cell lymphoma. (Source: Dermatologic Clinics)

Aug 27, 2015 04:00PM

Making the transition from thesis to published paper: A supervisor's note to her student

Navjeevan SinghIndian Journal of Dermatology, Venereology, and Leprology 2015 81(5):447-450 (Source: Indian Journal of Dermatology, Venereology and Leprology)

Aug 27, 2015 04:00PM

Therapeutic potential of biosimilars in dermatology

Vishal Gupta, Binod K KhaitanIndian Journal of Dermatology, Venereology, and Leprology 2015 81(5):451-456The introduction of biologic therapy has revolutionized the treatment of many chronic diseases, including several dermatological disorders. Biological agents promise to satisfy medical needs previously unmet by conventional medicines. Unfortunately, these agents are expensive and out of reach for the majority of patients who need them. Biosimilars are copies of the innovator biological agents and represent an important advance in the field of biological therapeutics. Although they are similar to the original biologic, differences in terms of structure, efficacy, safety and immunogenicity remain a concern. Thus, biosimilars cannot be regarded as bio-generics. Awareness of the key differe...

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Aug 27, 2015 04:00PM

Recent advances in topical formulation carriers of antifungal agents

Eman Ahmed Bseiso, Maha Nasr, Omaima Sammour, Nabaweya A Abd El GawadIndian Journal of Dermatology, Venereology, and Leprology 2015 81(5):457-463Fungal infections are amongst the most commonly encountered diseases affecting the skin. Treatment approaches include both topical and oral antifungal agents. The topical route is generally preferred due to the possible side effects of oral medication. Advances in the field of formulation may soon render outdated conventional products such as creams, ointments and gels. Several carrier systems loaded with antifungal drugs have demonstrated promising results in the treatment of skin fungal infections. Examples of these newer carriers include micelles, lipidic systems such as solid lipid nanoparticles and nanostructured lipid carriers, microemulsion...

Aug 27, 2015 04:00PM

Comprehensive lipid tetrad index, atherogenic index and lipid peroxidation: Surrogate markers for increased cardiovascular risk in psoriasis

Conclusion: Our results indicate that psoriasis, especially the severe variants, are associated with increased oxidative stress and dyslipidemia, which correlate positively with atherogenic index and hence, an increased cardiovascular risk. (Source: Indian Journal of Dermatology, Venereology and Leprology)

Aug 27, 2015 04:00PM

Controlled trial comparing the efficacy of 88% phenol versus 10% sodium hydroxide for chemical matricectomy in the management of ingrown toenail

Conclusion: Chemical matricectomy using NaOH is as efficacious as phenolisation, with the advantage of faster tissue normalization. (Source: Indian Journal of Dermatology, Venereology and Leprology)

Aug 27, 2015 04:00PM

Role of dental restoration materials in oral mucosal lichenoid lesions

Conclusion: Contact allergy to amalgam is an important etiologic factor in oral lichenoid lesions and removal of restorative material should be offered to patients who have lesions in close proximity to the dental material. (Source: Indian Journal of Dermatology, Venereology and Leprology)

Aug 27, 2015 04:00PM

Evaluation of role of Candida in patients with chronic paronychia

Conclusion: Our study shows that chronic paronychia is probably a form of hand dermatitis associated with prolonged wet work, and that there is a higher incidence of contact sensitization and Candida hypersensitivity in these patients. (Source: Indian Journal of Dermatology, Venereology and Leprology)

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Aug 27, 2015 04:00PM

Disseminated cutaneous phaeohyphomycosis due to Cladophialophora bantiana

We report a case of disseminated cutaneous phaeohyphomycosis caused by Cladophialophora bantiana in an immunocompromised female who presented with multiple pyogenic granuloma-like nodules, dermatophytosis-like plaque, and subcutaneous cysts on the upper and lower extremities without systemic involvement. Biopsy revealed black yeasts resembling sclerotic bodies and culture yielded irregular, velvety, grey colonies with black reverse. Excisionof the nodules and treatment with oral itraconazole 100 mg twice daily resulted in complete clinical resolution within two months, following which itraconazole was administered for another 4 months. (Source: Indian Journal of Dermatology, Venereology and Leprology)

Aug 27, 2015 04:00PM

Characteristics and outcomes of nonmelanoma skin cancer (NMSC) in children and young adults

Pediatric and young adult nonmelanoma skin cancer (NMSC) is rare and traditionally associated with predisposing heritable or congenital conditions. Clinical characteristics, outcomes, and iatrogenic risk factors have not been well described. (Source: Journal of the American Academy of Dermatology)

Aug 27, 2015 04:00PM

Generalized benign cutaneous reaction to cytarabine

Cytarabine-induced toxicity manifests as various cutaneous morphologies. A generalized papular purpuric eruption has not been well described. (Source: Journal of the American Academy of Dermatology)

Aug 27, 2015 04:00PM

In vitro model of infected stratum corneum for the efficacy evaluation of poloxamer 407-based formulations of ciclopirox olamine against Trichophyton rubrum as well as differential scanning calorimetry and stability studies

Publication date: 15 October 2015 Source:International Journal of Pharmaceutics, Volume 494, Issue 1 Author(s): Anja Täuber, Christel C. Müller-Goymann Superficial fungal skin infections are a common disease and concern 20?25% of the world's population with the dermatophyte Trichophyton rubrum being the main trigger. Due to autoinoculation, fungal skin infections of the feet (tinea pedis) often occur simultaneously with fungal nail infections (onychomycosis). Therefore, the overall objective was the development and characterisation of poloxamer 407-based formulations with the antimycotic active ingredient ciclopirox olamine (CPX) for simultaneous antifungal therapy. The formulations consisted of poloxamer 407, water, isopropyl alcohol, propylene glycol and medium chain triglyceride...

Aug 27, 2015 04:00PM

Possible intermediary role of ghrelin in seborrhea

This study aimed to explain hormonal changes occurring in gastroesophageal reflux disease which may cause changes in sebaceous gland secretion so that, by explaining these communication mechanisms, common investigations between gastroenterology and dermatology can be performed to evaluate the accuracy of this hypothesis. (Source: Medical Hypotheses)

Aug 27, 2015 04:00PM

Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin

by Horacio A. Ramirez, Liang Liang, Irena Pastar, Ashley M. Rosa, Olivera Stojadinovic, Thomas G. Zwick, Robert S. Kirsner, Anna G. Maione, Jonathan A. Garlick, Marjana Tomic-Canic Diabetes Mellitus (DM) is a chronic, severe disease rapidly increasing in incidence and prevalence and is associated with numerous complications. Patients with DM are at high risk of developing diabetic foot ulcers (DFU) that often lead to lower limb amputations, long term disability, and a shortened lifespan. Despite this, the effects of DM on human foot skin biology are largely unknown. Thus, the focus of this study was to determine whether DM changes foot skin biology predisposing it for healing impairment and development of DFU. Foot skin samples were collected from 20 patients receiving corrective foot sur...

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Aug 27, 2015 09:33AM

Effect of Bromine Substitution on Human Dermal Absorption of Polybrominated Diphenyl Ethers

Environmental Science & TechnologyDOI: 10.1021/acs.est.5b03904 (Source: Environmental Science and Technology)

Aug 27, 2015 04:06AM

Mother who picks her skin until it bleeds gets 27 tattoos to cover her hundreds of scars

Nicole Dobbie, 28, from Selkirk, Scotland, has dermatillomania, which causes her to spend hours every day scratching and picking at her own skin. The condition leaves her housebound. (Source: the Mail online | Health)

Aug 26, 2015 10:05PM

TNF??: a treatment target or cause of sarcoidosis?

Abstract Sarcoidosis is a systemic granulomatous disease that affects numerous organs, commonly manifesting at the lungs and skin. While corticosteroids remain the first line of treatment, tumour necrosis factor alpha (TNF??) inhibitors have been investigated as one potential steroid sparing treatment for sarcoidosis. TNF?? is one of many components involved in the formation of granulomas in sarcoidosis. While there have been larger scale studies of biologic TNF?? inhibition in systemic sarcoidosis, studies in cutaneous disease are limited. Paradoxically, in some patients treated with biologic TNF?? inhibitors for other diseases, treatment can induce the development of sarcoidosis. In the light of this complexity, we discuss the role of TNF?? in granuloma formation, the ther...

Aug 26, 2015 09:57PM

The role of Aldo?keto reductase 1C3 (AKR1C3)?mediated prostaglandin D2 (PGD2) metabolism in keloids

This article is protected by copyright. All rights reserved. (Source: Experimental Dermatology)

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Aug 26, 2015 09:00PM

Retraction of ?Development of Biomimetic Tilapia Collagen Nanofibers for Skin Regeneration through Inducing Keratinocytes Differentiation and Collagen Synthesis of Dermal Fibroblasts?

ACS Applied Materials & InterfacesDOI: 10.1021/acsami.5b07490 (Source: ACS Applied Materials and Interfaces)

Aug 26, 2015 09:00PM

DERMACINRX SURGICAL PHARMAPAK (Mupirocin Ointment Kit) Kit [PureTek Corporation]

Updated Date: Aug 27, 2015 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Aug 26, 2015 08:25PM

IL-2 Combo May Curb Cutaneous Metastatic MelanomaIL-2 Combo May Curb Cutaneous Metastatic Melanoma

A combination of intralesional interleukin (IL)-2, imiquimod, and topical retinoid prompted a complete local response in patients with cutaneous metastatic melanoma, and might improve survival, according to a small retrospective study. Reuters Health Information (Source: Medscape Dermatology Headlines)