Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care
2262 Camino Ramon, San Ramon, CA 94583
500 Alfred Nobel Drive, Suite #185, Hercules, CA 94547
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Fri, 31 Jul 2015 09:50:35 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Jul 31, 2015 01:45AM

Free Radical Threshold Value: A New Universal Body Constant

We present evidence for the existence of a universal free radical threshold value (FRTV), defining the borderline between advantageous and adverse effects of free radicals observed above the free radical ground state. Based on standard vitamin D doses, the calculated amount of ?3.5 × 1012 rad/mg ROS/LOS tissue represents the tolerated number of free radicals in skin tissue - defined as FRTV. By means of quantitative ESR x-band spectroscopy, the FRTV was experimentally verified using ex vivo human skin irradiated with ultraviolet + visible (UV + VIS), UVB + UVA and VIS light. In addition, we investigated whether this threshold is also existent in internal organs by extending our experiment to fresh porcine liver. Based on the determination of ROS/LOS below and above the FRTV, ROS > LOS w...

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Jul 31, 2015 01:43AM

Thermoresponsive Latexes for Fragrance Encapsulation and Release

ConclusionCrystalline?to?amorphous transition of PSA triggers the release of fragrances from cross?linked latex particles at elevated temperatures. The presence of the encapsulated fragrance, as well as the inclusion of amorphous fragments in the polymer network, reduces the particle crystallinity and enhances the release. Release profiles can be tuned by temperature and controlled by the amount of loaded fragrance and the ratio of comonomers in the feed mixture.This article is protected by copyright. All rights reserved. (Source: International Journal of Cosmetic Science)

Jul 31, 2015 01:42AM

Refractory acne keloidalis nuchae treated with radiotherapy

We report a case of AKN that had been refractory to various other treatments but which responded to RT with excellent clinical and cosmetic results. (Source: Australasian Journal of Dermatology)

Jul 31, 2015 01:16AM

LOP29: Dermal-Based Peripheral Nerve Interfaces for Transfer of Sensory Feedback from Prostheses

No abstract available (Source: Plastic and Reconstructive Surgery)

Jul 31, 2015 01:16AM

An Evidence-Based Model for the Successful Treatment of Flank and Lateral Abdominal Wall Hernias

Conclusions: The authors? data indicate successful results when their technique is applied. Proper patient selection is essential, along with a thorough understanding of anatomy and techniques for successful reconstruction. The authors recommend using an inlay (preferred) or underlay repair with acellular dermal matrix to reinforce the surrounding musculofascial closure. This technique, in conjunction with the authors? holistic abdominal wall reconstruction protocol, has optimized outcomes and identified a successful multidisciplinary strategy for the reconstruction of lateral wall defects. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. (Source: Plastic and Reconstructive Surgery)

Jul 31, 2015 01:16AM

Autologous Adipose Stromal Cells Seeded onto a Human Collagen Matrix for Dermal Regeneration in Chronic Wounds: Clinical Proof of Concept

Conclusions: Implantation of adipose-derived stromal cells seeded onto human acellular collagen matrix (biological dressing) represents a promising therapy for nonhealing wounds, offering improvement in dermal angiogenesis and remodeling. This therapy using autologous stromal cells is safe, without significant genetic alterations after in vitro expansion. (Source: Plastic and Reconstructive Surgery)

Jul 31, 2015 01:16AM

Embrace the Change: Incorporating Single-Stage Implant Breast Reconstruction into Your Practice

Conclusions: Breast reconstruction after mastectomy has evolved toward less invasive, single-stage procedures. Aesthetic refinements include nipple-sparing mastectomy, use of acellular dermal matrix, shaped implants, and fat grafting. Selected patients will benefit from a one-and-done breast implant reconstruction with no additional oncologic risk. Surgeons must embrace the change and provide their patients with a procedure that will offer the best aesthetic outcomes. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. (Source: Plastic and Reconstructive Surgery)

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Jul 31, 2015 12:10AM

Biological ageing, inflammation and nutrition: how might they impact on Systemic Sclerosis?

Authors: Shiels PG, Ritzau-Reid K Abstract The number of aged individuals within the global population is increasing, which foreshadows a major societal and global health challenge. By 2050 those over 65 years old will outnumber children under 15 years of age. This situation will bring with it multifarious variations in health and functional status, occurring with increasing age and which remain incompletely understood. Ageing, however, is not solely a passive degenerative process but one that is actively regulated by distinct molecular pathways. Understanding this molecular basis of ageing is an essential step for therapeutic manipulation to combat age-related disease. Diseases such as SSc, RA and SLE may share common age related pathways of early dysregulation with other diseases...

Jul 30, 2015 11:16PM

Cytotoxic effect and mechanism inducing cell death of ?-mangostin liposomes in various human carcinoma and normal cells

The aims of this study were to develop ?-mangostin liposomes as well as to evaluate their physicochemical properties and cytotoxic activity. ?-Mangostin liposomes were prepared using the reverse-phase evaporation method with lipid composition of phosphatidylcholine to cholesterol at 7?:?3 molar ratios; their physicochemical properties and antiproliferative activity were assessed using an MTT assay in four human carcinoma cells [that is, human lung epithelial carcinoma (Calu-3), human colon carcinoma (HT-29), human breast carcinoma (MCF-7), and human colon carcinoma (Caco-2) cells], and two human normal cells [that is, human dermal fibroblasts (HDF) and human adult low-calcium elevated temperature (HaCaT) keratinocytes]. Determinations of morphological changes and oligonucleosomal DNA...

Jul 30, 2015 11:05PM

Validation of the Japanese version of HFS-14, a disease-specific quality of life scale for patients suffering from hand-foot syndrome

Conclusions The Japanese HFS-14 provides a valid and reliable score for monitoring and evaluating HFS. (Source: Supportive Care in Cancer)

Jul 30, 2015 11:39AM

Primary Pineal Region Melanoma: Case Report and Review of the Literature

We report here the 20th case of primary pineal tumor and the third case that was totally removed among these 20 cases. Our case was of a 62-year-old man who had headache, dizziness, gait disorder, and the signs and symptoms of ICP arising because of hydrocephalus-like vomiting for 4 weeks before admission. His images showed a hyperdense mass plus hydrocephalus in computed tomographic scan, a hyperintense solid mass in MRI-T1, and hypointense mass lesionin MRI-T2 and FLAIR that significantly enhances the lesion after gadolinium administration in the pineal region. We operated him through the supracerebellar-infratentorial approach and we totally resected this solid mass by microsurgery. The tumor was interestingly black in color, and when the pathologist reported it as melanoma, we consulte...

Jul 29, 2015 08:32PM

Prostate Cancer as a chronic disease: cost-effectiveness and proper follow-up.

Authors: Guttilla A, Bortolami A, Evangelista L Abstract In western countries, prostate cancer (PCa) is the most common non-dermatological malignant disease in men. Bone metastases more often develop in patients with advanced PCa; the associated complications present a substantial disease and economic burden. Although the introduction of new therapeutic strategies have provided some advantages in terms of overall survival and quality of life in patients with metastatic PCa, the skeletal related events and side effects due to the therapies are associated with an important impact on the healthcare costs. In particular, the number of hospital admission, clinical consultation and the introduction of new expensive diagnostic modalities have changed the management of metastatic patients....

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Jul 29, 2015 04:00PM

Foxp3+ regulatory T cells are expanded in severe atopic dermatitis patients

This article is protected by copyright. All rights reserved. (Source: Allergy)

Jul 29, 2015 04:00PM

Immunological GABAergic interactions and therapeutic applications in autoimmune diseases

Publication date: Available online 29 July 2015 Source:Autoimmunity Reviews Author(s): Gérald J. Prud?homme, Yelena Glinka, Qinghua Wang Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. However, it is also produced in other sites; notably by pancreatic ? cells and immune cells. The function of GABA in the immune system is at an early stage of study, but exerts inhibitory effects that are relevant to autoimmune diseases. The study of GABAergic interactions in the immune system has centered on three main aspects: 1) The expression of GABA and the relevant GABAergic molecular machinery; 2) the in vitro response of immune cells; and 3) therapeutic applications in autoimmune diseases. T cells and macrophages can produce GABA, and express all the com...

Jul 29, 2015 04:00PM

Nonbullous Erythema Multiforme in Hospitalized Children: A 10?Year Survey

ConclusionsUnlike adult NBEM, the majority of pediatric NBEM is associated with medications, especially penicillin. This may be due to the frequent use of antibiotics in children. (Source: Pediatric Dermatology)

Jul 29, 2015 04:00PM

Acquired lymphangioma of the penis in a patient with severe phimosis

(Source: International Journal of Dermatology)

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Jul 29, 2015 04:00PM

Slow?growing tumor of the nail

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Hematohidrosis: insights in the pathophysiology

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

A case of bullous scabies misdiagnosed as acquired epidermolysis bullosa

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Ectopic extramammary Paget's disease on the head: case report and literature review

(Source: International Journal of Dermatology)

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Jul 29, 2015 04:00PM

Skin manifestations of primary hyperoxaluria: a case report

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Novel mutation in the XPC gene: a case report of a patient with xeroderma pigmentosum

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Unilateral nipple involvement in histoid leprosy

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Michelin tire baby syndrome: a case report

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Recurrent reactive angioendotheliomatosis in pregnancy: a case report

(Source: International Journal of Dermatology)

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Jul 29, 2015 04:00PM

A case of Bannayan?Riley?Ruvalcaba syndrome. A new clinical finding and brief review

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

New and emerging concepts in managing and preventing community?associated methicillin?resistant Staphylococcus aureus infections

Abstract Methicillin?resistant Staphylococcus aureus (MRSA) infections occurring within communities are increasing and can affect healthy individuals who have had little to no experience with hospital or healthcare settings (community?associated MRSA, CA?MRSA). CA?MRSA infections have multiple presentations which can make diagnosis and timely treatment difficult yet often manifest as a skin and soft tissue infection (SSTI) requiring dermatological intervention. There is emerging evidence of multiple environmental sources of bacteria that may contribute to recurrence. As with other infections, preventing transmission and recurrence depends on adherence to hand?washing and personal hygiene practices. Pharmaceutical intervention should be culture? rather than empirically?guided....

Jul 29, 2015 04:00PM

Our experience with a severe case of aplasia cutis congenita with a large skull defect

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

An unknown mass: the differential diagnosis of digit tumors

Abstract There is little discussion of tumors arising in the digits in the dermatology literature. The patient with an undifferentiated mass of the finger is frequently encountered in the clinic, and variances in presentation of common and uncommon entities pose a challenge that may prompt further investigation for proper diagnosis and treatment. In this review, the authors illustrate the approach and work?up of an unknown digit mass of a 45?year?old female patient. They go on to discuss the presentation and treatment of common tumor lesions of the finger likely to be encountered in the dermatologist's clinic including: ganglion cyst/mucous cyst, giant?cell tumor, verruca vulgaris, epidermal inclusion cyst, poroma, porocarcinoma, squamous cell carcinoma, basal cell carcinoma, melan...

Jul 29, 2015 04:00PM

Tattoo?induced psoriasis

(Source: International Journal of Dermatology)

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Jul 29, 2015 04:00PM

Childhood bullous pemphigoid: a report of three cases in China

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Fifty shades of yellow: a review of the xanthodermatoses

This article will focus on recognition of these entities, classified in terms of morphology and the site of initial eruption, in order to support the recognition and diagnosis of these widely variable conditions. (Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Vancomycin?induced linear IgA bullous dermatosis demonstrating the isomorphic phenomenon

(Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Chemokine MCP1/CCL2 gene polymorphism influences Henoch?Schönlein purpura susceptibility in Iranian Azeri?Turkish patients

ConclusionsMCP1/CCL2 C?2518T gene polymorphism is associated with susceptibility to HSP. This is the first study to report a significant association between MCP1/CCL2 C?2518T and a susceptibility to HSP in this population. (Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Quality of life: a research gap in teledermatology

Abstract An important outcome in healthcare, and in particular for dermatologic healthcare, is quality of life. Whereas the literature is well represented by quality of life assessments in dermatology, very little information is available that specifically addresses teledermatology's impact on quality of life. This gap in our knowledge of teledermatology is noteworthy precisely because of the importance that quality of life plays in dermatologic disease and healthcare delivery. The goal of this review is to briefly outline the concept of quality of life and its importance to dermatology, describe the different type of instruments that are used to assess quality of life, and to review studies that implemented teledermatology interventions and made quality of life assessments. The available ...

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Jul 29, 2015 04:00PM

Leprosy profiles in post?elimination stage: a tertiary care hospital experience

ConclusionMB cases with grade 2 deformities are in an upward trend, and rates of children are declining. Developing reinforced new therapies to curb reactions, deformities are very important and contact tracing, especially of children, is essential. Domiciliary treatment needs to be made available to ensure early diagnosis. (Source: International Journal of Dermatology)

Jul 29, 2015 04:00PM

Towards more efficient burn care: Identifying factors associated with good quality of life post-burn

Conclusion For clinicians managing comparable burn populations, the BSWA burns nomogram is an effective tool to assist the selection of patients to a streamlined care pathway with the aim of improving efficiency of service delivery. (Source: Burns)

Jul 29, 2015 04:00PM

Machine learning in burn care and research: A systematic review of the literature

Conclusion A common feature base may be determined for ML in burn care/research, but the impact of ML will require further validation in prospective observational studies and randomized clinical trials, establishment of common performance metrics, and high quality evidence about clinical and economic impacts. Only then can ML applications be advanced and accepted widely in burn care/research. (Source: Burns)

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Jul 29, 2015 04:00PM

A tribute to Cicero Parker Meek

Publication date: Available online 29 July 2015 Source:Burns Author(s): C. Ottomann, B. Hartmann, L. Branski, C. Krohn Cicero Parker Meek (1914?1979) was working as a general practitioner at the Aiken County Hospital in South Carolina, USA, and had a special interest in the treatment of burn patients. The procedure first presented in 1958 by Meek for a device-based expansion of split-skin (micrografting), which was invented before the mesh technique, is a milestone in the history of burns surgery. The method was forgotten until well into the 90s of the last century, and was only readopted and improved by no longer identifiable physicians at the Red Cross Hospital in Beverwijk. The Meek translation procedure was subsequently modified through the innovations of Kreis and Raff. With i...

Jul 29, 2015 11:29AM

What Is Microdermabrasion, And Will It Improve Your Skin?

"Beauty Glossary" is a HuffPost series that breaks down beauty product techniques, treatments and ingredients so you know exactly what you're putting onto and into your body.  Microdermabrasion is one of those cosmetic procedures that most people have heard of, but don't really know much about. Even if your skin-obsessed friend swears by it, or you've seen it listed on spa menus, the procedure is still one of those best discussed with a dermatologist. Allow us to clear up any misconceptions. Microdermabrasion is a procedure that exfoliates and removes the superficial layer of dry, dead skin cells. According to licensed medical aesthetician Maria Barry at Union Square Laser Dermatology, microdermabrasion machines can buff and polish the skin using a stream...

Jul 29, 2015 11:04AM

Effectiveness of silk fabric underwear as an adjuvant tool in the management of vulvar lichen simplex chronicus: results of a double-blind randomized controlled trial

Conclusions: Silk fabric underwear may be a useful tool for the management of VLSC by diminishing external sources of irritation and may reduce use of corticosteroids. (Source: Menopause)

Jul 29, 2015 08:00AM

Current Management of Scalp PsoriasisCurrent Management of Scalp Psoriasis

The majority of individuals with psoriasis will have scalp involvement. What therapies have proven benefit? Skin Therapy Letter (Source: Medscape Today Headlines)

Jul 29, 2015 05:32AM

Melanosis of the areola and nipple with an atypical pigment network

(Source: International Journal of Dermatology)

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Jul 29, 2015 05:32AM

Keloid Removal by Shave Excision With Adjuvant External Beam Radiation Therapy

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:32AM

A Novel Noninvasive Wound Closure Device as the Final Layer in Skin Closure

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:32AM

Nail Bed Reconstruction With Local Flaps After Full-Thickness Chemical Burn

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:32AM

Use of the Parell Frontal Sinus T-Stent to Prevent External Auditory Canal Stenosis

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:32AM

Intraoperative Real-Time Reflectance Confocal Microscopy for Guiding Surgical Margins of Lentigo Maligna Melanoma

No abstract available (Source: Dermatologic Surgery)

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Jul 29, 2015 05:31AM

Transposition?Advancement Flap for the Reconstruction of Segmental Auricular Defects

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

A Novel Suture Technique for High-Tension Wound Closure: The Tandem Pulley Stitch

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Book Review: Procedural Dermatology

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Polyotia: A Rare Disorder

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Reconstruction of Defects of the Posterior Pinna

No abstract available (Source: Dermatologic Surgery)

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Jul 29, 2015 05:31AM

Comparison of OnabotulinumtoxinA and RimabotulinumtoxinB for the Treatment of Axillary Hyperhidrosis

CONCLUSION: Both toxins showed comparable anhidrotic effect for the treatment of axillary hyperhidrosis at a conversion ratio of 1:30. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Subject Satisfaction With OnabotulinumtoxinA Treatment of Glabellar and Lateral Canthal Lines Using a New Patient-Reported Outcome Measure

CONCLUSION: High satisfaction rates are achieved and sustained in subjects treated with onabotulinumtoxinA for GL and CFL combined. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Duration of Effect by Injection Volume and Facial Subregion for a Volumizing Hyaluronic Acid Filler in Treating Midface Volume Deficit

CONCLUSION: VYC-20L is effective at restoring midface volume, with high subject satisfaction and an acceptable safety profile. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Delayed-Onset Nodules Secondary to a Smooth Cohesive 20 mg/mL Hyaluronic Acid Filler: Cause and Management

CONCLUSION: Although delayed nodules are uncommon from HA-V (0.5%), it is important to be aware of this adverse effect and have a management protocol in place. It is the authors' opinion from the patients' responses and from the literature that these nodules are immune mediated in nature. (Source: Dermatologic Surgery)

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Jul 29, 2015 05:31AM

Commentary on Laboratory Errors Leading to Nonmelanoma Skin Cancer Recurrence Following Mohs Micrographic Surgery

No abstract available (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Continuous Versus Interrupted Sutures for Facial Surgery Repair: A Randomized Prospective Study

CONCLUSION: Interrupted and continuous 5-0 nylon sutures result in an equivalent final cosmetic appearance of facial MMS scars. Given its advantages, running sutures may be the preferred closure technique for facial repair. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Laboratory Errors Leading to Nonmelanoma Skin Cancer Recurrence After Mohs Micrographic Surgery

CONCLUSION: Local recurrences after MMS are extremely rare. When recurrences do occur, they can be attributed to errors in histological interpretation or tumor mapping. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Retention of Mohs Surgeons in Academic Dermatology

CONCLUSION: Opportunities for intellectual stimulation, collaboration, and teaching remain the main draw for academic Mohs surgeons. A supportive environment, strong leadership, and establishing fair compensation are imperative in ensuring their stay. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Polypodium Leucotomos Supplementation in the Treatment of Scalp Actinic Keratosis: Could It Improve the Efficacy of Photodynamic Therapy?

CONCLUSION: Polypodium leucotomos improves PDT clearance and decreases AK recurrence rate at 6 months, suggesting its use as a complementary agent in the treatment of field cancerization. (Source: Dermatologic Surgery)

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Jul 29, 2015 05:31AM

Mohs Appropriate Use Criteria: Retrospectively Applied to Nonmelanoma Skin Cancers at a Single Academic Center

CONCLUSION: In a 3-month review of all NMSC cases at the academic center, there is a low percentage of cases performed that are inappropriate for MMS by AUC. At the institution, there is a large percentage of NMSC that meet AUC but are treated by other modalities. The use is highly appropriate for MMS, and these data suggest possible underutilization of MMS for certain NMSCs. Further studies are required to determine the effectiveness of other treatment modalities for NMSC that meet Mohs AUC. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

How to Review a Manuscript

CONCLUSION: Reviewing a manuscript for the journal is amenable to a simple algorithmic approach. Encouraging recent graduates and others to review for the journal by clarifying the process can further assist the editorial staff in selecting the best manuscripts and improving these before publication. (Source: Dermatologic Surgery)

Jul 29, 2015 05:31AM

Does Pregnancy After a Diagnosis of Melanoma Affect Prognosis? Systematic Review and Meta-analysis

CONCLUSION: Current evidence does not support the hypothesis that pregnancy subsequent to successful treatment of melanoma worsens prognosis. However, relevant data are sparse, suggesting that a precautionary approach is warranted regarding childbearing advice to melanoma survivors. (Source: Dermatologic Surgery)

Jul 29, 2015 05:29AM

Case of pemphigus with immunoglobulin G and A antibodies, binding to both the intercellular spaces and basement membrane zone

We report a case involving a 62?year?old woman with in vivo?bound immunoglobulin (Ig)G and IgA antibodies in both the intercellular space (ICS) and basement membrane zone (BMZ). Her clinical and histopathological features were identical with those of pemphigus vulgaris, while the immunopathological findings suggested IgG/IgA pemphigus. Direct immunofluorescence (IF) showed in vivo?bound IgG and IgA antibodies in the ICS and BMZ, whereas indirect IF showed circulating IgG but not IgA antibodies in the ICS and BMZ. The anti?ICS IgG bound to desmoglein?3, while the anti?BMZ antibodies bound to the epidermal side of 1 mol/L NaCl?split skin. To the best of our knowledge, only two similar cases have been reported so far. Furthermore, we also examined IgG subclass distribution ...

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Jul 29, 2015 04:35AM

Malignant Melanoma Arising in Red Tattoo Ink.

We report the case of a 33-year-old male who presented with a malignant melanoma on his anterior chest wall. The lesion was only found in the red ink pigment of the tattoo, as were several in-transit dermal metastases. Possible explanations include a pre-existing lesion which was seeded with red ink or the possibility of the red ink causing an inflammatory reaction leading to malignant transformation. This is the first reported case of a melanoma developing in the red ink pigment of a multi-colored tattoo. PMID: 26217569 [PubMed] (Source: Archives of Plastic Surgery)

Jul 28, 2015 11:28PM

A skin-picking disorder case report: a psychopathological explanation

We describe the case of a 44-year-old woman, without known previous psychiatric history, hospitalized after a significant hemorrhage caused by self-inflicted deep facial dermal lesions (with muscle exposition). Psychopathological possible explanations of this case, as in similar reviewed ones, are related to frustration, aggression, and impulsivity.Descrevemos um caso clínico de uma senhora de 44 anos de idade, sem antecedentes psiquiátricos prévios, internada após hemorragia significante causada por uma lesão facial autoinfligida (com exposição de músculo). Possíveis explicações psicopatológicas deste caso, tal como em casos similares, relacionam-se com frustração, agressividade e impulsividade. (Source: Jornal Brasileiro de Psiquiatria)

Jul 28, 2015 08:00PM

New 3-D human skin models could replace animal testing to assess dermal sensitivity to medical device

(Mary Ann Liebert, Inc./Genetic Engineering News) New research shows that exposing a 3-D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology. (Source: EurekAlert! - Biology)

Jul 28, 2015 04:00PM

Differential in situ expression of insulin?like growth factor?1 receptor in different histological subtypes of basal cell carcinoma: An immunohistochemical investigation

(Source: The Journal of Dermatology)

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Jul 28, 2015 04:00PM

Herpes zoster sciatica mimicking lumbar canal stenosis: a case report

Conclusion: In conclusion, spinal surgeons should keep in mind herpes zoster infection as one of the possible differential diagnoses of sciatica, even if there is no typical skin rash. (Source: BMC Research Notes)

Jul 28, 2015 04:00PM

Health related quality of life in patients with actinic keratosis – an observational study of patients treated in dermatology specialist care in Denmark

Conclusions: Patients with severe actinic damage showed more impairment in HRQoL than those with mild disease. Correlations between instruments suggest that they are complementary as they measure different aspects of HRQoL and are used for different purposes. (Source: Health and Quality of Life Outcomes)

Jul 28, 2015 04:00PM

Isolation and characterization of monoclonal antibodies specific for chondroitin sulfate E

In conclusion, the new anti-CSE monoclonal antibodies specifically recognize the E-unit of CSE. The antibodies will become useful tools for the investigation of the biological and pathological significance of CSE. (Source: Glycobiology)

Jul 28, 2015 04:00PM

Molecular survey of tick-borne pathogens in Ixodid ticks collected from hunted wild animals in Tuscany, Italy

Conclusions The results demonstrate the presence of several zoonotic tick-borne pathogens in the studied area, and underline the risk of exposure to infections for hunters not only during the outdoor activity, but also when they manipulate hunted animals infested by infected ticks. (Source: Asian Pacific Journal of Tropical Medicine)

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Jul 28, 2015 04:00PM

Impact of Screening for Hepatic Hemangiomas in Patients with Multiple Cutaneous Infantile Hemangiomas

ConclusionHepatic hemangiomas found through screening ultrasonography are less likely to develop serious clinical sequelae. Although the reasons for this may include detection of hemangiomas that are less likely to progress to symptomatic disease, it appears that it also allows for earlier intervention for more concerning (e.g. diffuse) subtypes. Screening may allow for closer surveillance and earlier treatment before life?threatening progression in a subset of infants with liver hemangiomas, preventing complications and reducing mortality. (Source: Pediatric Dermatology)

Jul 28, 2015 04:00PM

Imiquimod and Photodynamic Therapy Are Useful in the Treatment of Porokeratosis in Children with Bone Marrow Transplantation

We report two cases of porokeratosis in children with bone marrow transplant and their excellent response to imiquimod and photodynamic therapy. (Source: Pediatric Dermatology)

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Jul 28, 2015 04:00PM

Quantitative comparison of topical aluminum salt solution efficacy for management of sweating: a randomized, controlled trial

ConclusionIn a sweating simulation, 20% aluminum chloride hexahydrate quantitatively and objectively appeared to reduce sweat more effectively than 1% aluminum acetate. (Source: Journal of Cosmetic Dermatology)

Jul 28, 2015 04:00PM

Amplicon?based next?generation sequencing: an effective approach for the molecular diagnosis of epidermolysis bullosa

ConclusionsThe NGS and AmpliSeq were shown to be an effective approach for the diagnosis of EB, resulting in a cost? and time?effective 72?h procedure. (Source: British Journal of Dermatology)

Jul 28, 2015 04:00PM

The association between tumor necrosis factor???308 G/A polymorphism and risk for vitiligo: a meta?analysis

ConclusionsThis meta?analysis indicates that TNF???308 G/A polymorphism is not a genetic risk factor for vitiligo. (Source: International Journal of Dermatology)

Jul 28, 2015 04:00PM

Fusarium onychomycosis: prevalence, clinical presentations, response to itraconazole and terbinafine pulse therapy, and 1?year follow?up in nine cases

ConclusionsFusarium onychomycosis was clinically indistinguishable from other onychomycosis. Both itraconazole and terbinafine pulse therapy were only partially effective on Fusarium onychomycosis. Antifungals that are more effective should be sought. (Source: International Journal of Dermatology)

Jul 28, 2015 04:00PM

A novel continuous color mapping approach for visualization of facial skin hydration and transepidermal water loss for four ethnic groups

ConclusionsThere exists remarkable skin capacitance and TEWL gradients within short distances on selected areas of the face. These gradients are distinctive in the different ethnic groups. In contrast to other reports we found that darkly pigmented skin does not always have a superior barrier function and differences in skin hydration values are complex on the different parts of the face among the different ethnic groups.This article is protected by copyright. All rights reserved. (Source: International Journal of Cosmetic Science)

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Jul 28, 2015 04:00PM

Unilateral Stellate Purpura of the Ankle

This case report of a woman with unilateral stellate purpura of the ankle reveals how a complete skin examination is critical for diagnostic and prognostic purposes. (Source: JAMA Dermatology)

Jul 28, 2015 04:00PM

Pembrolizumab Cutaneous Adverse Events and Disease Progression

This study reports that pembrolizumab treatment is associated with cutaneous adverse effects in about 42% of patients and that patients who developed cutaneous adverse effects had significantly longer progression-free intervals vs those who did not develop such adverse effects. (Source: JAMA Dermatology)

Jul 28, 2015 04:00PM

Association of Psoriatic Disease With Uveitis

This nationwide cohort study reports a bidirectional associated increase in risk between psoriatic disease (including psoriasis and psoriatic arthritis) and uveitis among Danish adults with these exposures. (Source: JAMA Dermatology)

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Jul 28, 2015 01:31PM

Controversial Oxygen Therapy ZAPS Cancer

Get more oxygen into your blood, and it instantly destroys infections, bacteria, fungi, and viruses. Oxygen can even destroy cancer cells without harming healthy cells. In today’s world, getting oxygen to your cells is not as easy as it used to be. Even simple nutritional deficiencies like a lack of omega-3s can prevent oxygen from reaching your cells. When my new wellness center opens in October, I’m introducing several new oxygen therapies including an overlooked yet powerful technology called ozone therapy. But ozone is controversial. It attracts attention from the Feds because it WORKS. And anything that kills cancer naturally is going to bring heat from Big Pharma and Uncle Sam. Here in the U.S., the FDA has been trying to crush ozone therapy for over 70 years ? with the...

Jul 28, 2015 07:50AM

Occupational contact dermatitis caused by nickel in scratchcards

(Source: Contact Dermatitis)

Jul 28, 2015 07:00AM

Hypereosinophilic syndrome: an indolent rash with a serious cardiac complication

We present a case of idiopathic HES in a 30?year?old woman with asymptomatic multianeurysmal CAD and a sinus of Valsalva aneurysm, and discuss a brief review of the literature and management strategies. (Source: Clinical And Experimental Dermatology)

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Jul 28, 2015 05:35AM

An observational study of the real-life management of psoriasis patients treated with etanercept according to the new reimbursement criteria (in Belgium)

Journal of Dermatological Treatment, Ahead of Print. (Source: Journal of Dermatological Treatment)

Jul 28, 2015 04:02AM

Blue Rubber Bleb Nevus Syndrome Showing Vascular Skin Lesions Predominantly on the Face

An 81-year-old Japanese man presented with dark blue papules and nodules on his face. There were multiple soft papules and nodules, dark blue in color, compressive, and ranging in size from 2 to 10 mm. A few similar lesions were seen on the patient's right dorsal second toe and right buccal mucosa. There were no skin lesions on his trunk and upper limbs. The patient's past history did not include gastrointestinal bleeding or anemia. Histopathological examination showed dilated vascular spaces lined by the normal epithelium extending beneath the dermis and into the subcutaneous fat. Endoscopy of the gastrointestinal tract to check for colon involvement was not performed. X-ray images of the limbs revealed no abnormalities in the bones or joints. Laboratory investigations did not show anemia...

Jul 28, 2015 04:02AM

Elderly-Onset Generalized Pustular Psoriasis without a Previous History of Psoriasis Vulgaris

We report an 83-year-old man showing irregularly shaped erythema with pustules on the trunk and extremities. He initially had no fever and came to our clinic a few days after the onset of the skin lesions because of high fever and general malaise. We found an extension and new development of erythema and pustules on the whole body. The patient also manifested night delirium. Histological examination revealed neutrophil infiltration into the upper epidermis, which formed a spongiform pustule of Kogoj. Pustular fluid cultures were negative for bacteria. We diagnosed GPP without preceding psoriasis vulgaris. Mutation analysis revealed no significant mutations in IL36RN and CARD14. Previous reports indicated that onset of GPP at the age of 83 years is definitely rare. In older individuals, gen...

Jul 28, 2015 03:55AM

Risk of Cutaneous Squamous Cell Carcinoma Development in Renal Transplant Recipients Is Independent of TMC/EVER Alterations

Conclusion: To clarify the correlation between SNPs in both TMC genes and cSCC development in RTRs, integrated investigations of large cohorts including both RTRs and immunocompetent individuals with consideration of cSCC status, SNP genotype and human papillomavirus status might be necessary.Dermatology (Source: Dermatology)

Jul 27, 2015 07:20PM

Effects of Kyunghee Facial Resistance Program (KFRP) on mechanical and elastic properties of skin

Journal of Dermatological Treatment, Ahead of Print. (Source: Journal of Dermatological Treatment)

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Jul 27, 2015 04:00PM

An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease

ConclusionsThis is the first demonstration that keloid response to steroids can be measured objectively using noninvasive imaging. FLPI is a potentially reliable tool to stratify KD responsiveness. Altered GR expression may be the mechanism gating therapeutic response. (Source: British Journal of Dermatology)