Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care

2262 Camino Ramon, San Ramon, CA 94583
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Tue, 31 Mar 2015 14:54:38 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Mar 31, 2015 06:54AM

Nail Psoriasis in Children: Common or Uncommon? Results from a 10-Year Double-Center Study

Conclusions and Message: This is the retrospective study including the largest number of cases of nail psoriasis in the pediatric population. Our data are in line with the incidence estimation of the rest of Europe.Skin Appendage Disord 2015;1:43-48 (Source: Skin Appendage Disorders)

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Mar 31, 2015 06:54AM

Dyschromatosis Universalis Hereditaria with Renal Failure

We report a case of DUH with unexplained childhood-onset renal failure. The association between DUH and renal failure is yet to be proven by further studies.Case Rep Dermatol 2015;7:51-55 (Source: Case Reports in Dermatology)

Mar 31, 2015 06:51AM

Recent developments in the sensorial assessment of cosmetic products: a review

This article is protected by copyright. All rights reserved. (Source: International Journal of Cosmetic Science)

Mar 31, 2015 02:05AM

Paederus beetles: the agent of human dermatitis

Conclusions Paederus dermatitis is extremely frequent in villages with poor housing facilities and could be avoided via community awareness. (Source: Journal of Venomous Animals and Toxins including Tropical Diseases)

Mar 30, 2015 07:17PM

The experience of pain and redness in patients with moderate to severe plaque psoriasis

Journal of Dermatological Treatment, Ahead of Print. (Source: Journal of Dermatological Treatment)

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Mar 30, 2015 04:00PM

Coagulopathy in burn patients: One part of a deadly trio

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Athina Lavrentieva (Source: Burns)

Mar 30, 2015 04:00PM

Which factors influence the development of post-traumatic stress disorder in patients with burn injuries? A systematic review of the literature

Conclusion While it is possible to identify the factors that put burns patients are greater risk of developing PTSD, it is not possible to accurately predict who will go on to develop PTSD due to the interplay between variables and individual differences. Focus should instead be on screening for PTSD and timely recognition of intrusive symptoms. (Source: Burns)

Mar 30, 2015 04:00PM

Merits and challenges in the development of a dedicated burn service at a regional hospital in South Africa

Conclusion We have redesigned the process of care without alteration of resources. Outcomes of burns less than 30% total body surface area are not acceptable which we believe reflects the lack of infrastructure and systems development. This audit has revealed a number of areas, which are suitable for dedicated quality improvement initiatives. (Source: Burns)

Mar 30, 2015 04:00PM

Identification of factors that predict outpatient utilisation of a Plastic Dressing Clinic. A retrospective review of 287 paediatric burn cases

Conclusion Outpatient utilisation of the PDC can be predicted from burn characteristics. Full thickness burn, skin graft and pressure garment therapy are identified to significantly increase the number of PDC appointments following paediatric burn. (Source: Burns)

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Mar 30, 2015 04:00PM

Management of acid burns: Experience from Bangladesh

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Kishore Kumar Das , Loren Olga , Michael Peck , Paolo G. Morselli , A.J.M. Salek Acid burn injuries in Bangladesh primarily occur as a result of intentional attacks although there are incidences of accidental acid burns in industry, on the street, and at home. A total of 126 patients with acid burns, 95 from attacks and 31 from accidents, were studied from July 2004 to December 2012. A diagnosis of acid burn was made from history, physical examination and in some cases from chemical analysis of the patients? clothing. Alkali burns were excluded from the study. In the burn unit of Dhaka Medical College Hospital, we applied a slightly different protocol for management of acid burns, beginning with plain water irrigati...

Mar 30, 2015 04:00PM

Effect of oral olive oil on healing of 10?20% total body surface area burn wounds in hospitalized patients

This study showed that an oral diet provided with olive oil in patients with burn may accelerate wound healing and decrease the duration of hospitalization. (Source: Burns)

Mar 30, 2015 04:00PM

Petroleum pipeline explosions in sub-Saharan Africa: A comprehensive systematic review of the academic and lay literature

Conclusions Fire disasters related to scavenging fuel from petroleum pipelines are common in SSA and cause significant morbidity and mortality. These events require better reporting tools and intervention strategies overall. Furthermore, our study demonstrates that non-academic sources can effectively supplement gaps in the academic literature. (Source: Burns)

Mar 30, 2015 04:00PM

Quality of life of individuals treated in an outpatient burn treatment centre: Application of the BSHS-R

Conclusions Sociodemographic determinants have the greatest effect on determining the QOL of individuals who have suffered burns. Therefore, actions to promote education on preventing burns in workplaces and homes are needed. (Source: Burns)

Mar 30, 2015 04:00PM

Evaluation of TCOM/HBOT practice guideline for the treatment of foot burns occurring in diabetic patients

Conclusions While TCOM/HBOT therapy has not been widely applied to the management of diabetic foot burns, the use of an evidence-based guideline incorporating TCOM/HBOT can provide a systematic way to evaluate the patients? microcirculation and ability to heal burns of the foot. The incorporation of TCOM determination and application of HBOT in selected patients with DM and burns of the feet warrant continued study. (Source: Burns)

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Mar 30, 2015 04:00PM

Allogeneic mesenchymal stem cells, but not culture modified monocytes, improve burn wound healing

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Anthony J.P. Clover , Arun H.S. Kumar , Matthew Isakson , Derek Whelan , Alecia Stocca , Birgitta M. Gleeson , Noel M. Caplice The use of cell therapy to improve burn wound healing is limited as a validated cell source is not rapidly available after injury. Progenitor cells have shown potential to drive the intrinsic wound regeneration. Two sources of cells, allogeneic mesenchymal stem cells (MSC) and autologous culture modified monocytes (CMM), were assessed for their ability to influence burn wound healing. Both could be widely available shortly after injury. Cells were delivered in a fibrin matrix following contact burns in a porcine burns model. Application of MSC significantly decreased the area of unhealed burn ...

Mar 30, 2015 04:00PM

Non-severe burn injury leads to depletion of bone volume that can be ameliorated by inhibiting TNF-?

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Emily O?Halloran , Jasreen Kular , Jiake Xu , Fiona Wood , Mark Fear Bone loss after severe burn injury is well established, and is thought to be a consequence of the severe hyper-metabolic response as well as changes in cytokine and glucocorticoid levels that decrease bone synthesis and increase rate of loss. However, 90% of presentations are for non-severe burns which do not elicit this response. Little is known about whether these non-severe injuries may also affect bone tissue, and whether other mechanisms may be involved. To investigate whether bone loss occurs after a non-severe burn injury we used a mouse model of an approximately 8% total body surface area (TBSA) full-thickness burn and micro-CT. We also ass...

Mar 30, 2015 04:00PM

Genetically modified porcine split-thickness skin grafts as an alternative to allograft for provision of temporary wound coverage: preliminary characterization

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Angelo A. Leto Barone , Melissa Mastroianni , Evan A. Farkash , Christopher Mallard , Alexander Albritton , Radbeh Torabi , David A. Leonard , Josef M. Kurtz , David H. Sachs , Curtis L. Cetrulo Jr. Temporary coverage of severely burned patients with cadaver allograft skin represents an important component of burn care, but is limited by availability and cost. Porcine skin shares many physical properties with human skin, but is susceptible to hyperacute rejection due to preformed antibodies to ?-1,3-galactose (Gal), a carbohydrate on all porcine cells. Our preliminary studies have suggested that skin grafts from ?-1,3-galactosyltransferase knock out (GalT-KO) miniature swine might provide temporary wound coverage co...

Mar 30, 2015 04:00PM

Electroacupuncture at Zusanli (ST36) promotes gastric emptying and mucosal blood flow during oral resuscitation of scalded rats with a pyruvate-enriched ORS

Conclusion EA ST36 has a significant effect on improving gastric emptying and mucosal ischemia in the oral resuscitation of burn injury, possibly through the activation of a cholinergic nerve-dependent mechanism. In addition, EA ST36 showed no effects on motilin levels, but requires further investigations. (Source: Burns)

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Mar 30, 2015 04:00PM

A population-based study of the epidemiology of acute adult burns in Ecuador from 2005 to 2014

Conclusions Thermal burns are more frequent than any other cause of burns. Electrical burns are more frequent in Ecuador than anywhere else according to our research, meaning that control and prevention of workplace safety, urban planning, and home safety are scarce. The most affected groups are those dedicated to labor work. Finally, mortality in hospitalized patient is higher when compared with developed countries. Graphical abstract (Source: Burns)

Mar 30, 2015 04:00PM

Factors affecting the depth of burns occurring in medical institutions

Conclusion In burns occurring in medical institutions, there is a high probability of a deep burn if it is a contact burn or occurs in the lower body. Therefore, safety guidelines are needed for the use of hot packs, heating pads, and grounding pads to prevent such incidents. (Source: Burns)

Mar 30, 2015 04:00PM

Total cheek resurfacing with split ascending neck flap: A new approach

Conclusion Good cosmetic outcomes make this technique preferable for adults and children, and the technique is indicated as the first step for deformed cheek resurfacing for patients with uninjured neck. (Source: Burns)

Mar 30, 2015 04:00PM

Periorbital burns ? A 6 year review of management and outcome

Conclusion The goal in management of periorbital burns is preservation of vision, prevention of future complications and restoration of an acceptable aesthetic outcome. Total visual loss is thankfully rare, but early ophthalmology intervention is vital given the evidence of corneal damage as a brief therapeutic window exists. (Source: Burns)

Mar 30, 2015 04:00PM

Neck burn reconstruction with pre-expanded scapular free flaps

Conclusions The free tissue transfer of pre-expanded scapular flap is a valuable tool in neck burn reconstruction. It can be used safely and effectively with minimal morbidity in selected patients. (Source: Burns)

Mar 30, 2015 04:00PM

Our experiences on the reconstruction of lateral scalp burn alopecia with tissue expanders

Conclusion Although the number of case were limited, the ideal and standardized cosmetic results could be obtained by this approach. (Source: Burns)

Mar 30, 2015 04:00PM

A case series: Bilateral ischemic optic neuropathy secondary to large volume fluid resuscitation in critically ill burn patients

We present three patients with total body surface area (TBSA) thermal injury burns ranging from 57 to 68% treated at the North Carolina Jaycee Burn Center that developed bilateral ischemic optic neuropathy during their hospital stay. Each patient required greater than 25L of crystalloid fluid within 24h after admission, suffered multiple bouts of sepsis, and required extended pressor support. We postulate that ischemic optic neuropathy develops as a result of the interplay between the patient's systemic pathophysiology, i.e. shock, sepsis and the continued need for large volume fluid resuscitation. Current treatments of ION have not proven to be effective, except for possibly limiting fluid resuscitation. In the few cases of refractory burn shock, the incidence of this condition is unlikel...

Mar 30, 2015 04:00PM

Percutaneous pigtail catheter in the treatment of pneumothorax in major burns: The best alternative? Case report and review of literature

We present a case of a major burn patient who developed pneumothorax after central line insertion. After the traditional large bore (24Fr) chest tube failed to resolve the pneumothorax, the pneumothorax was ultimately managed by a percutaneous placed pigtail catheter thoracostomy placement and resulted in its complete resolution. We will review the current recommendations of pneumothorax treatment and will highlight on the use of pigtail catheters in pneumothorax management in burn patients. (Source: Burns)

Mar 30, 2015 04:00PM

Gut microbiota and environment in patients with major burns ? A preliminary report

Conclusions The gut microbiota and environment are severely altered in patients with major burns. Consequently, abnormal gut conditions may have an influence on the systemic inflammatory response and multiple organ dysfunction syndrome. A novel treatment to maintain the gut microbiota and environment is expected in the future. (Source: Burns)

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Mar 30, 2015 04:00PM

Mitral valve repair via right thoracotomy for multidrug resistant Pseudomonal endocarditis in a burn patient: Case report and review of the literature

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Jahan Mohebali , Amir E. Ibrahim , Thomas E. MacGillivray , Jeremy Goverman , Shawn P. Fagan Diagnosis and management of infectious endocarditis are particularly challenging in patients with severe burns. Cases requiring operative intervention are likely to have higher complication rates as a result of poor wound healing, recurrent bacteremia secondary to burn wound manipulation, and sequelae of anticoagulation in patients who require repeated reconstructive and cosmetic procedures. Few case reports exist describing mitral valve replacement for infectious endocarditis in burn patients. In this article, we review the literature to describe and address these challenges, and present what we believe to be the first case o...

Mar 30, 2015 04:00PM

Delivery and management of a preterm infant in the burn unit: A multidisciplinary approach

We report a case of severely burned female patient at 29 weeks gestation, who, due to deteriorating maternal condition, was delivered and managed at 32 weeks gestation by a multidisciplinary team. To the best of our knowledge this is the first reported case of a preterm infant delivered in a burn unit. (Source: Burns)

Mar 30, 2015 04:00PM

Patient confidentiality and new technologies in burn care

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): J.A. Dunne , J.M. Rawlins (Source: Burns)

Mar 30, 2015 04:00PM

Long shot suggestion for the treatment of extensive burns

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): D.A.A. Verkuyl (Source: Burns)

Mar 30, 2015 04:00PM

Self-immolation in Afghan females

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Mohsen Rezaeian (Source: Burns)

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Mar 30, 2015 04:00PM

Prevention of autologous skin graft loss

Publication date: May 2015 Source:Burns, Volume 41, Issue 3 Author(s): Ahmet Deniz Ucar , Erdem Bar?s Carti , Nazif Erkan , Mehmet Yildirim (Source: Burns)

Mar 30, 2015 04:00PM

Cooling of burns: Mechanisms and models

Publication date: Available online 26 March 2015 Source:Burns Author(s): E.H. Wright , A.L. Harris , D. Furniss The role of cooling in the acute management of burns is widely accepted in clinical practice, and is a cornerstone of basic first aid in burns. This has been underlined in a number of animal models. The mechanism by which it delivers its benefit is poorly understood, but there is a reduction in burns progression over the first 48h, reduced healing time, and some subjective improvements in scarring when cooling is administered after burning. Intradermal temperature normalises within a matter of seconds to a few minutes, yet the benefits of even delayed cooling persist, implying it is not simply the removal of thermal energy from the damaged tissues. Animal models have used oedem...

Mar 30, 2015 04:00PM

Home fire safety education for parents of newborns

Publication date: Available online 25 March 2015 Source:Burns Author(s): Carlee Lehna , Erin Fahey , Erika G. Janes , Sharon Rengers , Joseph Williams , Drane Scrivener , John Myers In children under 1 year of age, the proportion of unintentional burns increases with infant age and mobility. Infants are not able to avoid burns and are dependent on parental or adult help. Treatment of burns in young children is expensive in terms of the life-long costs. The purpose of this study was to examine changes in home fire safety (HFS) knowledge and practices over time for parents of newborn children and expecting parents. HFS knowledge of 103 parents was assessed at baseline, immediately after watching a DVD on HFS (recall), and at 2-week follow-up (retention). In addition, the United States Fire...

Mar 30, 2015 04:00PM

Acute discrimination between superficial-partial and deep-partial thickness burns in a preclinical model with laser speckle imaging

In this study, we report on the use of laser speckle imaging (LSI), a simple, non-invasive, optical imaging modality, to measure acute blood flow dynamics in a preclinical burn model. We used a heated brass comb to induce burns of varying severity to nine rats and collected raw speckle reflectance images over the course of three hours after burn. We induced a total of 12 superficial-partial and 18 deep-partial thickness burn wounds. At 3h after burn we observed a 28% and 44% decrease in measured blood flow for superficial-partial and deep-partial thickness burns, respectively, and that these reductions were significantly different (p =0.00007). This preliminary data suggests the potential role of LSI in the clinical management of burn wounds. (Source: Burns)

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Mar 30, 2015 11:57AM

Relationship of Leptin with adiposity and inflammation and Resistin with disease severity in Psoriatic patients undergoing anti?TNF?alpha therapy

ConclusionIn patients with moderate?to?severe psoriasis leptin correlates with metabolic syndrome features and inflammation whereas resistin correlate with inflammation and disease severity. (Source: Journal of the European Academy of Dermatology and Venereology)

Mar 30, 2015 11:54AM

Apocytolysis, a proposed mechanism of blister formation in epidermolysis bullosa simplex

Abstract Epidermolysis bullosa simplex (EBS) is caused by keratin 5 and 14 mutations. In vitro studies revealed that susceptibility to caspase 8-mediated apoptosis is increased in keratin 14 mutated keratinocytes. We aimed to investigate the role of apoptotic/inflammatory pathways in the pathogenesis of EBS by studying the expression of caspase 8 in lesional and non-lesional skin compared to controls. Ten EBS patients proved by electron microscopy and five age and sex matched healthy volunteers were the subjects of this case control study. Caspase 8 expression was studied by immunohistochemistry. Caspase 8 expression in lesional and non-lesional skin was significantly higher than in controls (p < 0.01 and p = 0.013, respectively) with no significant difference between lesio...

Mar 30, 2015 11:53AM

Biocompounds from Rapeseed oil industry co?stream as active ingredients for skin?care applications

ConclusionThe enzymatic technology applied to the rapeseed oil industry co?stream results in the release of bioactive compounds suitable for skin care applications.This article is protected by copyright. All rights reserved. (Source: International Journal of Cosmetic Science)

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Mar 30, 2015 11:08AM

Strip patch testing does not affect reaction profiles of standard allergens

ConclusionsReaction profiles of baseline series patch test substances remained largely unaffected by tape stripping the skin prior to patch testing. Thus, if conventional patch test results are presumed to be false?negative, performance of the strip patch test can be recommended independently of the standard allergen. (Source: Contact Dermatitis)

Mar 30, 2015 10:58AM

Supreme Court won?t hear IPAB challenge

The Supreme Court has declined to hear a case challenging the Independent Payment Advisory Board. (Source: Skin and Allergy News)

Mar 30, 2015 09:38AM

Here's What Would Really Happen If You Stopped Bathing

You've probably gone a few days without showering -- maybe a week. But let's say you didn't bathe for days on end -- as in you use no soap, no water, no nothing. What would happen? You're likely to get seriously stinky, for sure (though you may be surprised to learn that sweat itself is odorless). And that's only one of the things you'd have to worry about. Just check out the video above to find out about some of the more harmful -- even potentially deadly -- side effects of eliminating your hygiene routine. Video produced by Eva Hill. Script by Macrina Cooper-White. Voiceover by Dino Grandoni. Special thanks to: Dr. Lauren Ploch, Dr. Joshua Zeichner, Michael G. Schmidt, PhD., Julie Segre, PhD., Dr. Cameron K. Rokhsar, Compound Interest, American Academy of Dermatology. (Source: Sci...

Mar 29, 2015 04:00PM

FIB?SEM tomography of human skin telocytes and their extracellular vesicles

Abstract We have shown in 2012 the existence of telocytes (TCs) in human dermis. TCs were described by transmission electron microscopy (TEM) as interstitial cells located in non?epithelial spaces (stroma) of many organs (see www.telocytes.com). TCs have very long prolongations (tens to hundreds micrometers) named Telopodes (Tps). These Tps have a special conformation with dilated portions named podoms (containing mitochondria, endoplasmic reticulum and caveolae) and very thin segments (below resolving power of light microscopy), called podomers. To show the real 3D architecture of TC network, we used the most advanced available electron microscope technology: focused ion beam scanning electron microscopy (FIB?SEM) tomography. Generally, 3D reconstruction of dermal TCs by FIB?SEM tom...

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Mar 29, 2015 04:00PM

WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility

We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a binding partner for heat shock protein 90 (Hsp90). We now report that WISp39 has an essential function in the control of directed cell migration, which requires WISp39 interaction with Hsp90. WISp39 knockdown (KD) resulted in the loss of directional motility of mammalian cells and profound changes in cell morphology, including the loss of a single leading edge. WISp39 binds Coronin 1B, known to regulate the Arp2/3 complex and Cofilin at the leading edge. WISp39 preferentially interacts with phosphorylated Coronin 1B, allowing it to complex with Slingshot phosphatase (SSH) to dephosphorylate and activate Cofilin. WISp39 also regulates Arp2/3 complex localization at the leading edge. WISp39 KD-induced morphological chang...

Mar 29, 2015 04:00PM

Persistent Untreated Riga?Fede Disease for 6 Years

Abstract Riga?Fede disease is an uncommon, benign, ulcerative condition due to dental trauma that can occur at any age. A 9?year?old boy with a painful tongue is presented. Physicians need to recognize Riga?Fede disease and Riga?Fede?like disease to intervene early. (Source: Pediatric Dermatology)

Mar 29, 2015 04:00PM

Cutaneous Disease in Autism Spectrum Disorder: A Review

Abstract Dermatologic comorbid symptoms and conditions in persons with autism spectrum disorder (ASD) are compelling for several reasons, including problems with tactile sensory dysfunction in this population, a large number of syndromes with dermatologic findings and high rates of autism, nutritional and hormonal problems in ASD and their dermatologic manifestations, and the potential for overrepresentation of dermatologic symptoms that are neurobehavioral in nature. The current article reviews the available literature on the prevalence of comorbid dermatologic symptoms and conditions in children with ASD and identifies strategies for diagnosing and managing cutaneous disease in this population. (Source: Pediatric Dermatology)

Mar 29, 2015 04:00PM

Nomenclature for diseases with IgA anti?keratinocyte cell surface autoantibodies

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Mar 29, 2015 04:00PM

Chronic generalized fibrotic skin lesions from disseminated leishmaniasis caused by Leishmania martiniquensis in two HIV?infected patients from northern Thailand

ConclusionsL. martiniquensis is a cause of cutaneous leishmaniasis in Thailand.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Mar 29, 2015 04:00PM

Detection of Merkel cell polyomavirus's and other human polyomaviruses? DNA in lesional and non?lesional skin from Kaposi's Sarcoma patients

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Mar 29, 2015 04:00PM

Sarcoidosis presenting as non?scarring non?scalp alopecia

Abstract In this article we describe a 39?year?old man who presented with non?scarring non?scalp alopecia of his limbs as the initial presentation of sarcoidosis. Alopecia is a rare cutaneous manifestation of sarcoidosis. A literature review has found only one other example of sarcoidosis presenting as non?scarring non?scalp alopecia in an area other than the scalp in a patient who was otherwise asymptomatic. Several reported cases have described scarring alopecia of the scalp, which is the area of skin most commonly affected by sarcoidosis. There has been one documented case of sarcoidosis manifesting as total body non?scarring alopecia in a patient who had systemic symptoms of sarcoidosis. Other cases have presented rare cutaneous manifestations of sarcoidosis but in all th...

Mar 29, 2015 04:00PM

A 13?year retrospective study evaluating the efficacy of using air?fluidised beds for toxic epidermal necrolysis patients

ConclusionAir?fluidised beds can reduce the time to complete re?epithelialisation, relieve pain and increase the re?epithelialisation rate of TEN patients, but there was no significant difference between them in mortality rate in our study. (Source: Australasian Journal of Dermatology)

Mar 29, 2015 04:00PM

Atypical clinicopathologic presentation of primary cutaneous diffuse large B-cell lymphoma, leg type

Primary cutaneous diffuse large B-cell lymphoma, leg type (cDLBCL-LT) is a well-defined entity of cutaneous B-cell lymphoma affecting predominantly elderly patients, mostly women. The typical clinical presentation is characterized by solitary or multiple, rapidly growing plaques or tumors on 1 leg (rarely both legs). (Source: Journal of the American Academy of Dermatology)

Mar 29, 2015 04:00PM

Genital psoriasis is associated with significant impairment in quality of life and sexual functioning

Genital involvement has significant psychosexual implications for psoriasis patients. (Source: Journal of the American Academy of Dermatology)

Mar 29, 2015 04:00PM

National utilization patterns of Mohs micrographic surgery for invasive melanoma and melanoma in situ

Although wide local excision continues to be commonly used for melanoma treatment, Mohs micrographic surgery (MMS) for the treatment of melanomas remains controversial. (Source: Journal of the American Academy of Dermatology)

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Mar 29, 2015 04:00PM

Clinical and dermoscopic characteristics of melanomas on nonfacial chronically sun-damaged skin

Melanomas on chronically sun-damaged skin (CSDS) can be difficult to identify and often manifest morphologic features that overlap with benign lesions. (Source: Journal of the American Academy of Dermatology)

Mar 29, 2015 04:00PM

Nuclear actin aggregation is a hallmark of anti-synthetase syndrome-induced dysimmune myopathy

Conclusion: Antisynthetase syndrome–associated myositis is characterized by distinctive myonuclear actin filament inclusions, including rod formations and a typical necrotizing perimysial myositis. This supports the hypothesis that antisynthetase syndrome–associated myositis is unique and should not be grouped among dermatomyositis, polymyositis, sporadic inclusion body myositis, necrotizing autoimmune myositis, or nonspecific myositis. Classification of evidence: This study provides Class II evidence that for patients with IIMs, the presence of myonuclear actin filament inclusions accurately identifies patients with antisynthetase syndrome–associated myositis (sensitivity 81%, specificity 100%). (Source: Neurology)

Mar 29, 2015 04:00PM

Updating the epidemiology of dermatophyte infections in Palestine with special reference to concomitant dermatophytosis

Conclusions The epidemiology of dermatophytosis, especially tinea capitis, has gone the most radical changes in Palestine in the last three decades, with M. canis replacing T. violaceum, and becoming the predominant causative agent of all cases of infections. The coexistence of tinea pedis with other types of fungal skin infections is a frequent phenomenon; we believe that the infected foot may be a site of primary infection. Thus, the effective therapy for tinea pedis is essential to prevent spreading the infection to other sites of the skin. (Source: Journal of Medical Mycology)

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Mar 29, 2015 04:00PM

Surgical Treatment of Enormous Recurrent Dermatofibrosarcoma Protuberans

THORAC CARDIOV SURG ReportsDOI: 10.1055/s-0034-1387822A patient with enormous recurrent dermatofibrosarcoma protuberans underwent modified three-dimensional histology surgery. Frozen-section examination was used to identify the margins. The patient had a normal postoperative course.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: The Thoracic and Cardiovascular Surgeon Reports)

Mar 29, 2015 04:00PM

A novel, nonanaphylactogenic, bispecific IgE-CD3 antibody eliminates IgE B cells

IgE, the key pathogenic molecule underlying all allergic disorders, such as asthma and atopic dermatitis, represents an attractive target for therapeutic approaches. The protagonist omalizumab, a humanized anti-IgE mAb, has demonstrated moderate clinical benefit in asthmatic patients, and its effects are mainly characterized by decreased airway inflammation and reduced rate of exacerbation.1 (Source: Journal of Allergy and Clinical Immunology)

Mar 29, 2015 04:00PM

Livedoid vasculopathy and high levels of lipoprotein (a): response to danazol

We present four cases with LV who were successfully treated with low?dose danazol, assessing the clinical characteristics and laboratory tests including the level of LP(a). The average age of the patients was 45 years and the mean duration of the disease was 19 years. The treatment regime of danazol 200?mg daily led to complete healing of ulcers and reduction in pain and a 70% (ranging from 52 to 87%) reduction in the level of LP(a). The limitation of this study is ?small sample size.? In our patients with LV, low?dose danazol led to clinical improvement along with significant reduction in the level of LP(a). (Source: Dermatologic Therapy)

Mar 29, 2015 04:00PM

Andrographolide suppresses melanin synthesis through Akt/GSK3?/?-catenin signal pathway

(Source: Journal of Dermatological Science)

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Mar 28, 2015 10:15PM

Eosinophilic annular erythema limited on the palms and the soles and possibly associated with thymoma

(Source: Journal of the European Academy of Dermatology and Venereology)

Mar 28, 2015 10:15PM

Editorial board

(Source: Journal of Dermatological Science)

Mar 28, 2015 10:15PM

Announcements (only if available)

(Source: Journal of Dermatological Science)

Mar 28, 2015 10:15PM

The Editor's Choice

(Source: Journal of Dermatological Science)

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Mar 28, 2015 10:10PM

Tips to Treat the 5 Most Common Nail Disorders

This article therefore helps clinicians to find the right treatment of the 5 most common nail disorders (brittle nails, onycholysis, paronychia, psoriasis, and onychomycosis) and provides practical tips that might improve patients? compliance. (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Preface

Nails are a difficult topic for many dermatologists, and training in nail disorders is often scarce. The purpose of this issue of Dermatologic Clinics is to make nail diseases easy to diagnose and treat. This will definitely improve the good care of patients. (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Nail Disorders: Practical Tips for Diagnosis and Treatment

DERMATOLOGIC CLINICS (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Copyright

ELSEVIER (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Contributors

BRUCE H. THIERS, MD (Source: Dermatologic Clinics)

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Mar 28, 2015 10:10PM

Contents

Antonella Tosti (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Forthcoming Issues

Granulomatous Disorders of Adult Skin (Source: Dermatologic Clinics)

Mar 28, 2015 10:10PM

Index

Note: Page numbers of article titles are in boldface type. (Source: Dermatologic Clinics)

Mar 28, 2015 04:00PM

Clinical and image improvement of Raynaud's phenomenon after botulinum toxin type A treatment

We report two patients with severe or mild Raynaud's phenomenon who were injected with BTX?A; both of whom experienced clinical and image improvement after treatment. (Source: Australasian Journal of Dermatology)

Mar 28, 2015 04:00PM

Factors contributing to poor treatment outcomes in childhood atopic dermatitis

Abstract Atopic dermatitis (AD) is a chronic relapsing inflammatory disease of the skin and is the most common paediatric dermatological condition. While no cure is available, it can be treated effectively if adherence to a therapeutic plan is maintained. Poor adherence to treatment is common in AD and can lead to treatment failure, which has significant impacts on the patient, family and society. A comprehensive literature search was conducted to identify factors that contribute to poor treatment adherence in childhood AD and to identify possible strategies to remedy these. Identified factors leading to poor treatment adherence include: complexity of treatment regimen, lack of knowledge, impaired quality of life, dissatisfaction with treatment strategies, infrequent follow up, corticoster...

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Mar 28, 2015 12:51PM

Consider cephalosporin a safe alternative for patients with penicillin allergy

HOUSTON? Given the low incidence of adverse drug reactions to cephalosporin antibiotics among nearly a million California health plan patients, patients with a history of penicillin allergy can safely be given cephalosporins, according to Dr. Eric M. Macy. The recommendation is based on the... (Source: Skin and Allergy News)

Mar 28, 2015 12:09PM

A novel c.1037C > G (p.Ala346Gly) mutation in TP63 as cause of the ectrodactyly-ectodermal dysplasia and cleft lip/palate (EEC) syndrome

Ectrodactyly ? ectodermal dysplasia and cleft lip/palate (EEC) syndrome (OMIM 604292) is a rare disorder determined by mutations in the TP63 gene. Most cases of EEC syndrome are associated to mutations in the DNA binding domain (DBD) region of the p63 protein. Here we report on a three-generation Brazilian family with three individuals (mother, son and grandfather) affected by EEC syndrome, determined by a novel mutation c.1037C > G (p.Ala346Gly). The disorder in this family exhibits a broad spectrum of phenotypes: two individuals were personally examined, one presenting the complete constellation of EEC syndrome manifestations and the other presenting an intermediate phenotype; the third affected, a deceased individual not examined personally and referred to by his daughter, exhibite...

Mar 28, 2015 12:03PM

Analysis: ACA didn?t flood physicians? offices with new, sicker patients

Physicians experienced no major changes in patient volume or complexity since the Affordable Care Act?s coverage expansion provisions took effect, a study shows. Of patient encounters, 22.9% of primary care visits in 2014 were by new patients, compared with 22.6% of visits to primary care... (Source: Skin and Allergy News)

Mar 28, 2015 11:14AM

Ingestion of Portland cement - Kim KH, Lee JY, Yang SE, Lee WS, Sung WY, Seo SW, Yang JI.

In this study, we report a case of successful treatment of cement ingestion using emergency gastrointestinal endos... (Source: SafetyLit: All (Unduplicated))

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Mar 28, 2015 07:11AM

Commonwealth Fund: ACA?s medical loss ratio rule saves $5 billion

The Affordable Care Act?s requirement that health insurers pay out a minimum percentage of premiums in medical claims or quality improvement generated $5 billion in savings from 2011 to 2013, according to the Commonwealth Fund. However, insurance companies were not increasing spending on quality... (Source: Skin and Allergy News)

Mar 28, 2015 05:44AM

Interleukin-23 in the pathogenesis and treatment of psoriasis.

Authors: Kollipara R, Downing C, Gordon R, Tyring S Abstract In the past three decades, major advances have been made in understanding the pathogenesis of psoriasis. The currently accepted theory is that T-cell mediated immune dysregulation triggers keratinocyte hyperproliferation in psoriasis. Recent research indicates that the Th17/interleukin (IL)-23 pathway plays a prominent role in the amplification phase of psoriasis. The discovery of the Th17/ IL-23 pathway provides targets for new drug development. This review focuses on the role of IL-23 in psoriasis pathogenesis and the current therapies targeting IL-23 that are in clinical trials. PMID: 25807335 [PubMed - in process] (Source: Skin Therapy Letter)

Mar 28, 2015 05:44AM

Male aesthetics.

Authors: Keaney T Abstract Men are a fast growing segment of the aesthetic industry. A review was performed for publications on gender differences in facial anatomy, behavior, and the use of minimally invasive aesthetic procedures in men. There are substantial facial anatomical differences between genders with men having a larger but unique cranial shape, increased skeletal muscle mass, unique subcutaneous fat distribution, and more severe facial rhytides. Men also exhibit poor behavior that can accelerate aging including poor utilization of preventive health care services, higher rates of smoking, and increased ultraviolet light exposure. Despite gender differences in facial anatomy and behavior, few studies have examined the role of gender in cosmetic procedures. Men require a un...

Mar 28, 2015 05:36AM

Glove use among hairdressers: difficulties in the correct use of gloves among hairdressers and the effect of education

ConclusionsHairdressers and apprentices lack knowledge on how to handle gloves correctly. A short demonstration of correct glove use made a significant difference in the skin protection provided by gloves. (Source: Contact Dermatitis)

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Mar 28, 2015 04:46AM

Conservative management of a traumatic superficial temporal artery aneurysm

(Source: Clinical And Experimental Dermatology)

Mar 28, 2015 02:36AM

Cutaneous Manifestations of Human Immunodeficiency Virus: a Clinical Update

This article reviews the current spectrum of HIV-associated skin conditions, focusing on common complaints, infections, drug-associated toxicity and malignancies. (Source: Current Infectious Disease Reports)

Mar 28, 2015 02:36AM

Skin Infections in Returned Travelers: an Update

Abstract Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians? unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are primarily dermatologic. First, the evolving epidemiology of these infections is examined; understanding the geographic distribution of infectious etiologies helps refine and narrow the differential diagnosis. This is followed by a discussion of six important clinical syndromes including cutaneous larva migrans (CLM), cutaneous leishmaniasis, tungiasis, myiasis, antibiotic-resistant skin and soft tissue infection, and selected infections associated with feve...

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Mar 27, 2015 10:29PM

State of the Art and Science in Postmastectomy Breast Reconstruction

Conclusion: Innovative approaches to breast reconstruction have evolved to provide restorative healing for patients and hasten return to their modern, active lifestyles. (Source: Plastic and Reconstructive Surgery)

Mar 27, 2015 04:00PM

Histopathological findings and detection of Toll-like receptor 2 in cutaneous lesions of canine leishmaniosis

The objective of this descriptive study was to characterize and compare the inflammatory pattern, the Leishmania burden and expression of TLR2 in skin lesions derived from dogs with different clinical stages of leishmaniosis and cutaneous lesions. Routine histology, Leishmania and TLR2 immunohistochemistry assays were performed in 11 patients with papular dermatitis (stage I-mild disease) and 10 patients with other cutaneous lesions (stage II-III-moderate to severe disease). A significantly higher frequency of granuloma formation was demonstrated in skin samples of dogs with stage I when compared with dogs of stage II-III. Although not statistically significant, a trend for a lower parasite burden was observed for skin lesions of dogs with stage I when compared with dogs of stage II-III. A...

Mar 27, 2015 04:00PM

Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

Conclusions: Consequently, areas with a lowered infection pressure due to IVM MDA appear to influence bystander responses to Plasmodium-derived antigens in community members even if they have not regularly participated in the therapy. (Source: Parasites and Vectors)

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Mar 27, 2015 04:00PM

Incidence rates of atopic dermatitis, asthma, and allergic rhinoconjunctivitis in Danish and Swedish children

Several studies have shown that the prevalence of the frequent chronic conditions of atopic dermatitis, asthma, and allergy has increased substantially for reasons not fully understood. Atopic diseases affect quality of life in both children and their family members. (Source: Journal of Allergy and Clinical Immunology)

Mar 27, 2015 04:00PM

Surgical management of extranasal nasal glioma

(Source: Journal of the European Academy of Dermatology and Venereology)

Mar 27, 2015 04:00PM

Ingenol mebutate gel is effective against anogenital warts ? a case series in 17 patients

(Source: Journal of the European Academy of Dermatology and Venereology)

Mar 27, 2015 12:42PM

Health risk assessment of heavy metals contamination in tomato and green pepper plants grown in soils amended with phosphogypsum waste materials

Abstract Phosphogypsum (PG) is a waste produced by the phosphate fertilizer industry that has relatively high concentrations of some heavy metals (e.g., Cd, Cr, Cu, Pb, V, and Zn). The present study was conducted to investigate heavy metal contamination in soils and vegetables (tomatoes and green peppers) and to evaluate the possible health risks associated with the consumption of vegetables grown in PG-amended soils. The enrichment factor values indicated that Pb, Cr, Cu, Ni, Zn, and V were depleted to minimally enriched, and Cd was moderately enriched. The pollution load index values indicated that the PG-amended soils were strongly polluted with Cd, moderately polluted with Cr and Ni, and slightly polluted with Pb, Cu, Zn and V. The geo-accumulation index values indicated that...

Mar 27, 2015 11:42AM

Penile Cancer in a Man With Netherton Syndrome

Netherton syndrome (NS) is a rare autosomal recessive skin disease with severe skin inflammation and scaling, a specific hair shaft defect (trichorrhexis invaginata or bamboo hair), and severe atopic manifestations including atopic dermatitis and hay fever with high serum immunoglobulin E levels and hypereosinophilia. NS is caused by loss-of-function mutations in serine protease inhibitor of Kazal-type 5 (SPINK5) encoding lympho-epithelial Kazal-type?related inhibitor (LEKTI) expressed in the stratified epithelia. (Source: Urology)

Mar 27, 2015 11:04AM

Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs.

Authors: Pucheu-Haston CM, Eisenschenk MN, Bizikova P, Marsella R, Nuttall T, Santoro D PMID: 25808534 [PubMed - in process] (Source: Veterinary Dermatology)

Mar 27, 2015 11:04AM

Review: Lymphocytes, cytokines, chemokines and the T-helper 1-T-helper 2 balance in canine atopic dermatitis.

CONCLUSIONS: The development of AD in dogs is characterized by the development of a delicate balance between a variety of T-cell phenotypes and inflammatory mediators, including cytokines, chemokines and noncytokine factors. PMID: 25808535 [PubMed - in process] (Source: Veterinary Dermatology)

Mar 27, 2015 05:04AM

Diagnostic Dilemma in Primary Blastomyces dermatitidis Meningitis: Role of Neurosurgical Biopsy

A 52-year-old male on chronic prednisone for polymyalgia rheumatica presented with a subacute history of headaches, nausea, phonophobia, intermittent diplopia and gait instability. He was hospitalized 2 weeks prior to presentation with extensive evaluations only notable for leptomeningeal inflammation on MRI. His symptoms progressively worsened and he developed aphasia. He was transferred to our facility where extensive spinal fluid examinations were repeated and were again nondiagnostic. Ultimately, a diagnostic skull-based biopsy was performed which demonstrated Blastomyces dermatitidis fungal meningitis. Despite extensive sampling and cultures, only 1 of the intraoperative samples yielded diagnostic results. This underscores the low sensitivity of current methods to diagnose CNS blastom...

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