Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care

2262 Camino Ramon, San Ramon, CA 94583
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

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(email staff to get your personal passcode)

* Patient Biopsy Results via LabCalls


MEDICAL DERMATOLOGY

Acne and Acne Scar

Excimer Laser for Psoriasis & Vitiligo

Keloid & Hypertrophic Scar Laser Therapy

Mohs Surgery for Skin Cancers

Nail Fungus GenesisPlus Laser Therapy

Photodynamic Therapy

Psoriasis & NBUVB Phototherapy

RadioTherapy Nonsurgical SRT-100 for Skin Cancer

Skin Allergy Patch Test

Sweating Disorder MiraDry for Hyperhidrosis

Wart Laser Therapy


COSMETIC DERMATOLOGY

Aesthetician Services
Microdermabrasion
 

Botox, Dysport & Xeomin

Cellulaze Cellulite Therapy

new! CoolSculpting

Facial Redness/Vein Laser Therapy

Fillers injection for Wrinkles

Fractional CO2 laser

new! Hair Transplant with Neograft

Laser Surgery Services
Acne/Pore reducing Laser
Collagen Stimulating Laser
Excimer Laser
Facial Veins laser
Hair Laser Removal
IPL Fotofacial
Melasma Laser
Nail Fungus Laser
Resurfacing Laser
Scar revision Laser
SmartLipo Laser
Tattoo Laser
VBeam Pulse Dye Laser
Wart Laser


Latisse

Leg Vein Laser Therapy & Asclera Sclerotherapy

Liposonix + Vaser Shape Nonsurgical Body Sculpting
 

Melasma and Pigmentation

Pore Size Reduction and Laser Rejuvenation

Sculptra Liquid Facelift

new! SideLaze Lift

SmartLipo Laser Tumescent Liposuction

Ulthera natural lift & skin tightening of face and neck


Related Websites
FaceUpLifting.com
iSmartLipo.com
iCellulaze.com
MoreHair4Me.com
SideLazeLift.com
SonixLipo.com


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925-328-0255

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* Review Dr. Ting's 717+ Q&A on RealSelf

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra Laser for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Thu, 17 Apr 2014 21:12:41 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Apr 17, 2014 01:12PM

Table of Contents

(Source: Journal of the American Academy of Dermatology)

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Apr 17, 2014 01:12PM

Information for Readers

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Dermatology Calendar

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Localized bullous fixed drug eruption following yellow fever vaccine

To the Editor: Yellow fever is a potentially fatal, mosquito-borne disease endemic to areas of South America and Africa. The yellow fever vaccine is recommended to those traveling to high-risk areas and is considered one of the safest and most effective vaccines ever developed. The vaccine is a live attenuated version of the 17D strain grown in egg embryos and imparts durable immunity for 10 years. Reported dermatologic side effects of the vaccine include mild injection site reactions, urticaria, and anaphylaxis. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Iotaderma #244

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

April iotaderma (#243)

(Source: Journal of the American Academy of Dermatology)

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Apr 17, 2014 01:12PM

Editorial Board

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Treatment of molluscum contagiosum with ingenol mebutate

Molluscum contagiosum (MC) is a common and benign contagious viral skin condition of childhood that accounts for approximately 1% of all diagnoses of skin disorders and up to 10% of skin disorder diagnoses in the pediatric population (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

A unique protective bandage for preauricular surgery

Creating a pressure dressing for preauricular surgery can be difficult because of the anatomy of the ear and nearby hair. This dressing is indicated for scars located in the preauricular region, between the apex of the helix and ear lobe, 3 cm from the pinna?s anterior implantation (tragus; , A). After covering the surgical scar with ointment and sterile gauze (, B), the bandage is fixed in a vertical direction with hypoallergenic adhesive tape (25 × 12 mm; , C). (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Brimonidine effective but may lead to significant rebound erythema

We report a case of facial erythema of rosacea that responded well to this medication, however, rebounded with significantly greater erythema than baseline for the patient. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Trigeminal trophic syndrome secondary to recurrent meningioma

To the Editor: A 45-year-old man with a history of childhood acute lymphocytic leukemia and radiation-induced bilateral recurrent meningiomas requiring resection in 2001 and resection and Gamma-Knife in 2010 presented with a 4-week history of unexplained facial ulcerations followed by the development of headaches. He reported waking with ?bloody lesions? on his face, which were preceded by facial pain he rated on a scale of 1 to 10 as an 8. He denied pruritus and picking his face. His headaches were associated with left-sided photophobia and facial numbness. Physical exam revealed a red, ulcerated, indurated left tragus. Scattered 5- to 10-mm annular pink atrophic scars with peripheral hyperpigmentation were seen on the left cheek, forehead, and nose (). A 2- x 1-cm superficial ulcerat...

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Apr 17, 2014 01:12PM

Striking leflunomide efficacy against refractory cutaneous sarcoidosis

We describe leflunomide efficacy in 2 patients whose cutaneous sarcoidoses were refractory to conventional therapies. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Painless papules on the hands

A 56-year-old man presented with a 6-month history of a progressive asymptomatic papular eruption that began on the dorsal surfaces of his thumbs (, A). The physical examination revealed hundreds of monomorphic firm, clustered 1- to 2-mm skin-colored papules that were symmetrically distributed on the dorsal surfaces of his hands, arms, upper back, neck, and forehead (, B). The hands were notable for skin thickening over the proximal interphalangeal joints (, C). A skin biopsy specimen obtained from a papule on the dorsal surface of one of his hands revealed marked fibroblast proliferation and increased collagen with separation of fibers in the papillary dermis (, A, hematoxylin and eosin stain) caused by diffuse dermal mucin (, B, alcian blue stain). Serum thyroid studies were within norma...

Apr 17, 2014 01:12PM

A woman with pruritic papules in her tattoo

A 46-year-old woman presented with a 3-month history of pruritic, burning papules within a 10-year-old tattoo. The physical examination revealed a large, multicolored tattoo across her back with discrete papules in the black portion (). Tender, red subcutaneous nodules were present on the anterior aspect of the lower legs. The patient developed systemic symptoms, including low-grade fevers, fatigue, chest pain, arthralgias, shortness of breath, and cough. A computed tomography scan of the chest was performed, and it revealed bilateral hilar lymphadenopathy. Pertinent laboratory tests include an elevated serum angiotensin-converting enzyme titer at 80 U/L (reference range, 8-53 U/L). Punch biopsy specimens were obtained from the mid-back tattoo and a left dorsal thumb papule (). (Source: Jo...

Apr 17, 2014 01:12PM

Uncovering a hidden basal cell carcinoma

The routine clinical examination of a 63-year-old man with a 3-year history of plaque psoriasis (PP) revealed numerous erythematous scaly papules and plaques on the trunk and extremities (). (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Adhesive tape technique to enhance potassium hydroxide diagnosis of occult fungal infections

Most potassium hydroxide (KOH) preparations are readily executed and interpreted. Occasionally, hyphae are few or none. When the lesion is clinically suspect of fungal disease and KOH negative, we use adhesive tape not to take a specimen for direct examination but to produce a moist environment under occlusion. Fungal infections generally occur in moist or warm areas because fungi can easily flourish under such conditions. We apply plastic tape to the active outer border of their lesion and request that the patient reattach this tape with additional tape whenever it loosens (). Fungi therefore flourish under the tape. After 2 to 3 days, there will be a high quality sample for examination, which enables a physician to identify mycelia and spores. This simple technique provides a satisfacto...

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Apr 17, 2014 01:12PM

Vacation dermatoses

A 6-year-old boy presented with an intensely pruritic rash on his left lower extremity after vacationing in Costa Rica (). He was seen in a local urgent care center, and over the course of 2 weeks was treated with multiple antibiotic ointments and oral antibiotics with no improvement. His mother reported that the patient frequented the beach while in Costa Rica, and that there were often stray dogs on the beach. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Important Notice Regarding JAAD Grand Rounds

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

JAAD Grand Rounds quiz? Adult with vesicles and bullae

Learning objectives: At the conclusion of this learning activity, physician participants should be able to assess their own diagnostic and patient management skills and use the results of this exercise to help determine personal learning needs.Instructions: In answering each question, refer to the specific directions provided. Because it is often necessary to provide information occurring later in a series that give away answers to earlier questions, please answer the questions in each series in sequence. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Necrotic plaques in a traveler

A 76-year-old man presented to the emergency department with a 5-day history of severe supraorbital headaches, significant muscle weakness, continuous fevers, and nonpainful ulcers on his right leg. His symptoms began 2 days after returning from a hunting trip to the rural area between Durban and Port Elizabeth, South Africa. The patient?s travel partner also had been having fevers since their return. The physical examination revealed 2 purpuric plaques with a central ulceration and black eschar involving the right medial aspect of the upper thigh and the right popliteal fossa (). There was palpable lymphadenopathy in the right groin. A punch biopsy specimen obtained from the right popliteal fossa lesion was bisected and sent for both routine histology () and culture. A histopathologic e...

Apr 17, 2014 01:12PM

Expression of programmed death receptor ligand 1 in melanoma may indicate tumor progression and poor patient survival

To the Editor: Melanoma is characterized by a high potential to metastasize at low primary tumor volumes and by a high resistance to conventional therapies. One reason for this is that the tumor microenvironment can protect tumor cells from immune surveillance by a mechanism called ?tumor evasion.? Programmed death receptor ligand 1 (PD-L1) plays an important role in this mechanism by negatively regulating T-cell function. Aberrant PD-L1 expression has been described in melanoma, but its prognostic relevance remains controversial. Therefore, we aimed to analyze PD-L1 expression in melanoma and evaluate its relationship with prognosis. (Source: Journal of the American Academy of Dermatology)

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Apr 17, 2014 01:12PM

Change of Address

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Ductal hypoxia in acne: Is it the missing link between comedogenesis and inflammation?

Two visions of the etiopathogenesis of acne vulgaris and acne inversa exist. The traditional considers the main driver of acne to be androgens, causing excess proliferation of sebocytes and ductal keratinocytes. The impact of androgens on the components of the folliculopilosebaceous unit (FPSU) has been known for decades. Androgens induce the proliferation of the ductal keratinocytes in the follicular canal. This expanding plug of compact keratin stretches the duct to its maximal circumference, anoxia occurs, the duct leaks and ruptures, keratin and other stimuli are released into the dermis, the toll-like receptors of the innate immune system are activated, and inflammation follows. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Maintenance of certification in dermatology?what we know, what we don't

To the Editor: The Federation of State Medical Boards (FSMB) appreciates the article about the value of lifelong learning and the overview of the FSMB's Maintenance of Licensure (MOL) initiative. As several state medical boards begin to study the implementation of MOL, it is important to recognize that our recommendations do not include, as the article suggests, a ?proctored examination.? The MOL framework adopted in 2010 by FSMB's member boards does not require physicians to take examinations to comply with MOL. While an exam may be an option that some physicians wish to utilize to demonstrate their knowledge and skills in their area of practice, we do not believe such an exam should be mandatory to renew a state medical license. (Source: Journal of the American Academy of Dermatology...

Apr 17, 2014 01:12PM

Comment on ?A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis?

To the Editor: Recently, the University of Ottawa?s Division of Dermatology (Canada) reviewed ?A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis? by Pariser et al during our monthly journal club. While we commend the authors on several fronts, the conclusion of the article seems disconnected from the data presented. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

A response to "Comment on ?A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis?"

To the Editor: The letter of Drs Sauder, Beecker, and Ramsay makes some points with which I agree. This small trial was an attempt to address the lack of controlled clinical data for cutaneous sarcoidosis. The choice of adalimumab was based on a believable pathophysiologic rationale and on anecdotal reports. The concern that adalimumab has been associated with the onset of sarcoidosis seems questionable. Do we avoid adalimumab in patients with psoriasis because it has been associated with the onset of pustular psoriasis in some individuals with rheumatoid arthritis? (Source: Journal of the American Academy of Dermatology)

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Apr 17, 2014 01:12PM

Robotic teledermatopathology from an African dermatology clinic

In this study, we summarize our experience with nearly 300 cases seen via the robotic telepathology system in Gaborone, Botswana (in which the microscope is controlled and slides are viewed remotely by the consulting pathologist) and attempt to gauge its impact on the care of patients with dermatologic conditions in that country. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

The ethical implications of ?more than one way to skin a cat? Increasing use of radiation therapy to treat nonmelanoma skin cancers by dermatologists

Dr Will B. Rich (Dr R) runs a successful dermatology practice but is intrigued by the possibility of increasing his profits in an environment of declining reimbursements. A representative from a company visits his office and introduces him to a novel way to treat skin cancer with a relatively new Food and Drug Administration (FDA)-approved radiation device. The company representative advises Dr R that this technology will allow him to retain patients rather than refer them to a Mohs surgeon for the treatment of nonmelanoma skin cancers (NMSCs). The actual treatment will be performed by a radiation oncologist whose fee is much less than the code the company suggests Dr R use for reimbursement. Dr R realizes that this procedure has the potential to significantly diversify his practice and to...

Apr 17, 2014 01:12PM

American Board of Dermatology Examination Dates

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Answers to CME examination

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

CME examination

(Source: Journal of the American Academy of Dermatology)

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Apr 17, 2014 01:12PM

The spectrum of oculocutaneous disease: Part II. Neoplastic and drug-related causes of oculocutaneous disease

There are a multitude of diseases that commonly affect both the skin and the eye. Part II of this 2-part series reviews the oculocutaneous manifestations of neoplasms, both benign and malignant, and adverse drug reactions affecting the skin and the eye. Though rare, a number of neoplasms that primarily involve the skin, such as melanoma and basal cell carcinoma, can metastasize to the eye, leading to permanent damage if not properly treated. In addition, periocular neoplasms can irritate the conjunctiva and lid, reducing a patient's ability to see clearly. Neoplastic diseases, such as xeroderma pigmentosum, Sturge?Weber syndrome, and multiple myeloma, can also lead to permanent changes in the eye if not discovered and managed promptly. Furthermore, there are a multitude of drugs, includi...

Apr 17, 2014 01:12PM

CME examination

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

Answers to CME examination

(Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 01:12PM

The spectrum of oculocutaneous disease: Part I. Infectious, inflammatory, and genetic causes of oculocutaneous disease

Many skin diseases are associated with ocular findings, emphasizing the need for dermatologists to be fully aware of their presence, and as a result, avoid overlooking conditions with potentially major ocular complications, including blindness. We review important oculocutaneous disease associations with recommendations for the management of the ocular complications and appropriate referral to our ophthalmology colleagues. Part I of this 2-part review focuses on the infectious, inflammatory, and genetic relationships. (Source: Journal of the American Academy of Dermatology)

Apr 17, 2014 06:06AM

Propeller flap reconstruction of abdominal defects: Review of the literature and case report

The abdominal wall is perfused anteriorly by the superior and deep epigastric vessels with a smaller contribution from the superficial system. The lateral abdominal wall is perfused predominantly from perforators arising from the intercostal vessels. Reconstruction of soft tissue defects involving the abdomen presents a difficult challenge for reconstructive surgeons. Pedicle perforator propeller flaps can be used to reconstruct defects of the abdomen, and here we present a thorough review of the literature as well as a case illustrating the perforasome propeller flap concept. A patient underwent resection for dermatofibrosarcoma protuberans resulting in a large defect of the epigastric soft tissue. A propeller flap was designed based on a perforator arising from the superior deep epigastr...

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Apr 17, 2014 02:42AM

Clinical Quality Measures and Meaningful Use

No abstract available (Source: Advances in Skin and Wound Care)

Apr 17, 2014 02:42AM

New Products

No abstract available (Source: Advances in Skin and Wound Care)

Apr 17, 2014 02:42AM

The Toenail: The Distal End of Human Oxygenation

No abstract available (Source: Advances in Skin and Wound Care)

Apr 16, 2014 04:00PM

Randomized controlled trial to evaluate the effects of ethyl-2-cyanoacrylate on pain intensity and quality of life in head and neck cancer patients suffering from cetuximab-induced rhagades during radioimmunotherapy: the support trial

DiscussionDuring treatment with EGFR inhibitors it is necessary to recognize and manage side effects promptly to assure better patient QoL. The SUPPORT trial is the first randomized clinical trial evaluating a new treatment option for painful cetuximab-induced rhagades. Furthermore, the new SUPO score will be prospectively assessed in terms of clinical usefulness for classification of EGFR inhibitor-induced rhagades.Trial registration: Current Controlled Trials NCT01693159. (Source: BMC Cancer)

Apr 15, 2014 11:15PM

Dermoscopic features of dermatofibrosarcoma protuberans.

Authors: Avilés-Izquierdo JA, Conde-Montero E, Barchino-Ortiz L, Lázaro-Ochaita P PMID: 24720426 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

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Apr 15, 2014 11:15PM

A retrospective review of the therapeutic response with remission in patients with newly diagnosed bullous pemphigoid.

Authors: Chuah SY, Tan SH, Chua SH, Tang MB, Lim YL, Neoh CY, Tan AW Abstract We reviewed the clinical characteristics and therapeutic response in cases of newly diagnosed bullous pemphigoid at the National Skin Centre between June 2009 and December 2010. Most (76%, n?=?68/90) achieved clinical remission within 6 months of commencement of therapy. Oral mucosal involvement was identified as a risk factor associated with a prolonged duration of treatment beyond 6 months. PMID: 24720427 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

Apr 15, 2014 11:15PM

In other journals.

Authors: Watson A PMID: 24720428 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

Apr 15, 2014 11:15PM

Appearance of de novo dysplastic spitzoid compound naevus in an adalimumab-treated psoriatic patient: Case report and review of the possible causal relationship with TNF-? blockers.

Authors: Sousa M, Freitas JP, Antunes J, Soares-de-Almeida L, Filipe PL PMID: 24720429 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

Apr 15, 2014 11:15PM

Verrucous skin lesions on the feet in diabetic neuropathy: Successful treatment using a hollowed-out sponge.

Authors: Yamauchi K, Kobayashi T, Kawakubo C, Fujimoto N, Takahiro S, Tajima S PMID: 24720430 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

Apr 15, 2014 11:15PM

Penile lentigo (genital mucosal macule) following annular lichen planus: a possible association?

Authors: Isbary G, Dyall-Smith D, Coras-Stepanek B, Stolz W PMID: 24720431 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

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Apr 15, 2014 11:15PM

Male frontal fibrosing alopecia with generalised hair loss.

Authors: Chen W, Kigitsidou E, Prucha H, Ring J, Andres C Abstract Frontal fibrosing alopecia predominantly affects postmenopausal women and is regarded as a variant of lichen planopilaris. Male cases have rarely been reported. Here we describe a 66-year-old man with a typical receding fronto-temporal hair line in a form of scarring alopecia, which shows features of lichen planopilaris in histology. An extensive loss of body hair involving bilateral axillae, limbs and pubic area was also observed. PMID: 24720432 [PubMed - in process] (Source: The Australasian Journal of Dermatology)

Apr 15, 2014 04:00PM

Contrasting echogenicity in flexor digitorum profundus?flexor carpi ulnaris: A diagnostic ultrasound pattern in sporadic inclusion body myositis

Conclusions: FDP?FCU echogenicity contrast in muscle US is a sensitive diagnostic indicator of s?IBM. Muscle Nerve 49: 745?748, 2014 (Source: Muscle and Nerve)

Apr 15, 2014 04:00PM

Effect of sitting position on equal?dose spinal anaesthetic for caesarean section and post?partum tubal ligation

ConclusionThe same dose of hyperbaric bupivacaine 12?mg and morphine 100??g administered in the sitting position to both PPTL and CS parturients yielded similar maximal sensory blocks, but PPTL exhibited faster block regression and less hypotension/vasopressor requirement. (Source: Acta Anaesthesiologica Scandinavica)

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Apr 15, 2014 04:00PM

Dermoscopy as an adjuvant tool for detecting skin leiomyomas in patient with uterine fibroids and cerebral cavernomas

Conclusions: This observation highlights the usefulness of dermoscopy in the diagnosis of cutaneous leiomyomas disclosing multiple cutaneous and uterine leiomyomatosis syndrome. Dermoscopy should be performed for non-melanocytic multiple lesions mimicking leiomyomas in a large number of patients, to establish a strict classification and identify false negative cases or evaluate them as dermatofibromas. In this case, the dermatologist recognized the risk of renal cancer and cerebral cavernomas. (Source: BMC Dermatology)

Apr 15, 2014 04:00PM

The spectrum of skin diseases in a black population in Durban, KwaZulu?Natal, South Africa

ConclusionAcne, eczemas, dyschromias, infections, and hair disorders are, in that order, the five most common disorders encountered. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Focal epithelial hyperplasia associated with human papillomavirus 13 and common human leukocyte antigen alleles in a Turkish family

ConclusionThis report is the first step for the investigation of involvement of HLA types in the pathogenesis of Turkish patients with FEH. (Source: International Journal of Dermatology)

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Apr 15, 2014 04:00PM

Antinuclear antibodies in atopic dermatitis: a cross?sectional study on 346 children

ConclusionNo significant differences were observed between AD and the control group, or between different subtypes of AD in ANA prevalence. In both groups, ANA frequency increased with age, but in patients with AD, ANA had a tendency to appear earlier. Therefore, active AD during the early years of life could dispose selected patients towards earlier development of systemic autoreactivity and stress the need for regular follow?up of patients with ANA?positive AD. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Acute generalized exanthematous pustulosis induced by clopidogrel

(Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Post?kala?azar dermal leishmaniasis in pregnancy: hitherto unaccounted

(Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Occult tinea pedis in an Israeli population and predisposing factors for the acquisition of the disease

ConclusionsThe prevalence of occult tinea pedis is similar to that of clinical tinea pedis. This may imply that patients with subclinical infection carry a risk for transmitting disease similar to that of clinical carriers. This is of great importance in the prevention and management of the disease as high?risk asymptomatic carriers can be identified. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Dermoscopy of angioma serpiginosum: a case report

(Source: International Journal of Dermatology)

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Apr 15, 2014 04:00PM

Artefactual skin lesions in children and adolescents: review of the literature and two cases of factitious purpura

ConclusionThe presence of purpura in children and adolescents typically causes extensive intervention programs due to the possible serious pathological consequences. The two cases demonstrate a need for a high degree of attention to psychological disturbances, lesional evolution, and distribution once the suspicion is established. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Nodular cutaneous mucinosis associated with systemic lupus erythematosus

(Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long?term follow?up

ConclusionFrontal fibrosing alopecia is increasingly seen in postmenopausal women and rarely in men. Despite the limitations of a retrospective study, we conclude early intervention and treatment with intralesional triamcinolone acetonide may halt the progression of the disease; however, further controlled prospective studies are needed to establish treatment guidelines for frontal fibrosing alopecia. (Source: International Journal of Dermatology)

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Apr 15, 2014 04:00PM

Cost?efficacy of biologic therapies for moderate to severe psoriasis from the perspective of the Taiwanese healthcare system

ConclusionsIn a Taiwanese setting, adalimumab and ustekinumab had lower 1?year costs per PASI 75 responder than etanercept, and ustekinumab had the lowest 2?year cost per PASI 75 responder. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Periorbital edema

(Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Assessment of quality of life in patients with psoriasis: a study from Serbia

ConclusionOur results support the importance of assessing the quality of life in psoriasis and effects of stress in patients' adjustment to their condition and may have important implications for a psychological stress management approach in the clinical management of psoriasis. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Darier's disease with cystic changes in the kidney

(Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

Antibiotic resistance in acne: is it time to look beyond antibiotics and Propionobacterium acnes?

(Source: International Journal of Dermatology)

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Apr 15, 2014 04:00PM

Comparative study of the effect of narrowband ultraviolet B phototherapy plus methotrexate vs. narrowband ultraviolet B alone and methotrexate alone in the treatment of plaque?type psoriasis

ConclusionsCombination of NBUVB plus MTX provided rapid improvement with less cumulative doses of both therapies compared with each one alone in the treatment of psoriasis. (Source: International Journal of Dermatology)

Apr 15, 2014 04:00PM

The first Mal de Meleda case in Libya: identification of a SLURP1 mutation

(Source: International Journal of Dermatology)

Apr 15, 2014 11:42AM

Spinal and supraspinal processing of thermal stimuli: An fMRI study

ConclusionSpinal fMRI successfully demonstrates increased spinal activity and secondary changes in activation of supraspinal centers involved in pain modulation caused by peripheral nociceptor sensitization.J. Magn. Reson. Imaging 2014. © 2014 Wiley Periodicals, Inc. (Source: Journal of Magnetic Resonance Imaging)

Apr 15, 2014 09:01AM

Periorbital papules and erythematous?brownish plaques on the neck and axilla

(Source: Journal of the European Academy of Dermatology and Venereology)

Apr 15, 2014 06:20AM

A case of stings in humans caused by Sclerodermus sp. in Italy

In the last years, stings of Sclerodermus species in humans have been sporadically reported in Italy. In order to draw attention to these bethylid wasps of medical importance, we report the case of documented Sclerodermus sp. stings on the dorsum, abdomen, arms, and thighs of a 40-year-old man and his wife. The sting sites developed raised red itchy rash. The source of environmental contamination was identified in a worm-eaten sofa purchased from a used furniture dealer and placed in the living room about a month and half earlier. The lesions on the man and his wife rapidly healed within 3 to 4 days once they left the house and treatment for the lesions was instituted. Physicians, dermatologists, medical and public health entomologists, as well as specific categories of workers should be a...

Apr 14, 2014 09:00PM

DERMA 1 HEALTHCARE HAND WASH (Chloroxylenol) Liquid [Woodbine Products Company]

Updated Date: Apr 15, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Apr 14, 2014 05:22PM

Hawaii dermatologist reopens former Kapolei practice under new ownership

Hawaii dermatologist Dr. Alex S. Carcamo has bought a practice that he originally opened for U.S. Dermatology in Kapolei and reopened the office on Monday as its new owner. Complete Dermatology is located 1001 Kamokila Blvd., across the street from Kapolei Regional Park. Carcamo had been with U.S. Dermatology of Hawaii, which is headquartered in Arlington, Texas. He opened the office in Kapolei in 2010 for the company, which closed it last year. Carcomo ended up purchasing two U.S. Dermatology? (Source: bizjournals.com Health Care:Hospitals headlines)

Apr 14, 2014 04:00PM

Extended negative pressure wound therapy-assisted dermatotraction for the closure of large open fasciotomy wounds in necrotizing fasciitis patients

Conclusions: Extended NPWT-assisted dermatotraction advances scarred, stiff fasciotomy wound margins synergistically in NF and allows direct closure of the wound without complications. This method can be another good treatment option for the NF patient with large open wounds whose general condition is unsuitable for extensive reconstructive surgery. (Source: World Journal of Emergency Surgery)

Apr 14, 2014 04:00PM

Increased serum level of N?terminal Pro?B?type natriuretic peptide as a possible biomarker of cardiovascular risk in psoriatic patients

ConclusionsThe study findings confirmed higher NT?proBNP concentrations in psoriatic patients, which could be a useful biomarker of CV disease in both normo? and hyperlipidaemic groups. (Source: Journal of the European Academy of Dermatology and Venereology)

Apr 14, 2014 04:00PM

Systemic sclerosis after silicone injections for facial cosmetic surgery

(Source: Journal of the European Academy of Dermatology and Venereology)

Apr 14, 2014 04:00PM

Current practice of methotrexate use for psoriasis: results of a worldwide survey among dermatologists

ConclusionCurrent clinical practice of methotrexate use in psoriasis is not uniform, depends on geographical location, and is not in full agreement with clinical guidelines. (Source: Journal of the European Academy of Dermatology and Venereology)

Apr 14, 2014 04:00PM

Infected urachal cyst in an adult

An otherwise healthy 34-year-old man presented with a 2 day history of lower abdominal pain. Abdominal examination revealed periumbilical tenderness. No umbilical purulent discharge or erythema was noted. Contrast enhanced CT revealed an enhanced, fluid filled cystic lesion extending up to umbilicus (figures 1, 2), and cyst cultures grew Klebsiella pneumoniae. A diagnosis of infected urachal cyst was established. The urachus, which usually disappears during fetal life, is used by the fetus for communication between the bladder and umbilicus. Urachal remnants are rare anomalies, with an estimated incidence of 2%, and if present, commonly accompanied by urachal cysts1; however, they usually remain clinically silent unless infection develops. Symptoms are often non-specific but include purule...

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Apr 14, 2014 04:00PM

Phantom first metacarpal

A 65-year-old man presented with a 1-month history of left hand pain, erythema and swelling over the thenar eminence. He had a history of moderately differentiated squamous cell carcinoma of the oesophagus, T3 N1 and was under oncology. Left hand x-ray (figure 1) showed complete destruction of the first metacarpal bone consistent with bony metastasis. Metastasis to the hand and wrist bones represents around 0.1% of all bone metastasis. It most commonly occurs after lung (42%), kidney (11%) and breast (11%) cancers.1 Metastasis from oesophageal cancer is an even rarer entity. We identified four previous cases in literature. Three of those involved the distal phalanges and one the scaphoid bone, but none of them involved a metacarpal bone. Metastasis to the metacarpal is known to be less fre...

Apr 14, 2014 04:00PM

Frostbite from frosting

A child presented to the emergency department with circular burns to both hands. History revealed participation in a game testing ability to withstand discomfort associated with close proximity discharge of aerosol canister. Examination revealed two circular partial thickness burns (0.5–1% TBSA) (figure 1). The recreational practice of ‘frosting’ (‘having a frosty’) involves the discharging of pressurised aerosol contents onto body surfaces.1 Reinforcement mechanisms include recreational substance abuse (inhalational euphoria), ‘curiosity’ or simply a misguided peer endurance test. Isolated cases have been reported, however, prevalence is likely under-reported. Resultant frostbite depends on duration of exposure and absolute temperature reached; ti...

Apr 14, 2014 04:00PM

Unremitting abdominal pain: obscure until the first CT

We present a patient with a clinical entity that deserves better recognition, first suspected by its typical imaging findings. The case A healthy elderly patient presented with several months’ history of diffuse abdominal pain of mild to moderate intensity becoming relentless with time with no associated weight loss, fever or anorexia. Examination, X-rays, laboratory tests, gastroscopy and colonoscopy were normal and no diagnosis was reached over several months. On admission, abdominal CT revealed lymphadenopathy (up to 3.0x1.5 cm) and mesenteric fat infiltration suggestive of sclerosing mesenteritis (SCM) (figure 1). Extensive laboratory studies and chest... (Source: Postgraduate Medical Journal)

Apr 14, 2014 04:00PM

Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease

The interstitial lung diseases (ILD) include a large number of chronic, progressive, irreversible respiratory disorders involving pulmonary fibrosis, the most common of which are idiopathic pulmonary fibrosis and scleroderma lung disease (SSc ILD). Because bleomycin causes lung fibrosis when used in cancer chemotherapy, it is used to model human ILD in rodents. In most studies, bleomycin has been delivered directly into the lung by intratracheal or intraoral administration. Here we have compared the effects in mice of bleomycin delivered directly into the lungs (direct model) or systemically using osmotic minipumps (pump model) to determine which more closely resembles human ILD. The pump model is more similar to human SSc ILD in that: 1) lung injury/fibrosis is limited to the subpleural p...

Apr 14, 2014 04:00PM

Clinical spectrum of females with HCCS mutation: from no clinical signs to a neonatal lethal form of the microphthalmia with linear skin defects (MLS) syndrome

Conclusion: Our findings showed a wide phenotypic spectrum ranging from asymptomatic females with an HCCS mutation to patients with a neonatal lethal MLS form. Somatic mosaicism and the different ability of embryonic cells to cope with an OXPHOS defect and/or enhanced cell death upon HCCS deficiency likely underlie the great variability in phenotypes. (Source: Orphanet Journal of Rare Diseases)

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Apr 14, 2014 04:00PM

Editor's Choice

(Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Shared decision making in dermatology: asking patients, ?What is important to you??

(Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

The outstanding record of clinical trials in the British Journal of Dermatology

(Source: British Journal of Dermatology)

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Apr 14, 2014 04:00PM

The association between beta?blockers and melanoma survival: evidence of absence or absence of evidence?

ORIGINAL ARTICLE, p 930 (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Diagnosing and treating psoriatic arthritis: an update

Summary Psoriatic arthritis (PsA) is an inflammatory arthritis of uncertain pathogenesis, affecting approximately one in four patients with psoriasis. Onset of psoriasis typically precedes the development of PsA. Therefore, the dermatologist is ideally positioned to recognize the early signs and symptoms of PsA for diagnosis and subsequent treatment. The role of the dermatologist in early diagnosis and treatment is essential for preventing pain and functional disabilities, as well as the joint deterioration that accompanies progressive forms of PsA. Diagnosis of PsA is a key aspect of the clinical decision process for the dermatologist, as psoriasis plus PsA requires a different therapeutic approach from that required for psoriasis alone. Furthermore, PsA is associated with an increased ri...

Apr 14, 2014 04:00PM

Applicability of dermoscopy for evaluation of patients' response to nonablative therapies for the treatment of superficial basal cell carcinoma

ConclusionsRDADC accurately predict residual disease. Absence of dermoscopic criteria of sBCC safely predicts complete histopathological clearance. Detection of white/red structureless areas and/or superficial fine telangiectasias warrants close monitoring to recognize early recurrence. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Inflammasome activation and vitiligo/nonsegmental vitiligo progression

ConclusionsOur findings suggest that markers of the NLRP1 inflammasome could be a useful test for assessing disease activity in addition to the detection of inflammatory infiltrates in the progressing margins of vitiligo/NSV lesions. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Factors associated with pruritic papular eruption of human immunodeficiency virus infection in the antiretroviral therapy era

ConclusionsPruritic papular eruption in HIV?infected persons receiving ART for ? 15 months was associated with greater HIV viraemia at ART commencement, independent of CD4 count. Skin biopsies are important to distinguish between PPE and other itchy papular eruptions. (Source: British Journal of Dermatology)

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Apr 14, 2014 04:00PM

Fractional carbon dioxide laser resurfacing of rhytides and photoageing: a prospective study using profilometric analysis

ConclusionsAfter a serial treatment with the fractional CO2 laser, we measured considerably varying wrinkle reduction depending on the area of the face, and the best results were found for the cheeks. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Histopathological analysis and clinical correlation of drug reaction with eosinophilia and systemic symptoms (DRESS)

ConclusionsThe severe dyskeratosis detected in patients with DRESS may correlate with a greater extent of systemic involvement compared with that noted in MPE. However, the histopathological changes associated with DRESS are not entirely specific. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Impact of mitotic activity on the pathological substaging of pT1 cutaneous melanoma

ConclusionsThe addition of mitotic activity to the pathological staging system, according to the seventh edition of the AJCC staging system, resulted in a considerable change in the classification of thin cutaneous melanomas. This shift has clear clinical implications, as it is advised in the Dutch guideline that patients with pT1b melanoma should be offered a sentinel lymph node biopsy. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

The prevalence of inverse recurrent suppuration: a population?based study of possible hidradenitis suppurativa

ConclusionsData on IRS suggest that HS may be more prevalent than previously suggested, and the prevalence may be comparable to other major dermatoses, e.g. psoriasis. However, as no physician examination was done, the risk of recall and information bias is a major limitation. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

Aplasia cutis congenita with dystrophic epidermolysis bullosa: clinical and mutational study

ConclusionsOur findings suggest that ACC is a frequent manifestation in patients with DEB irrespective of the severity of the disease, and is due to leg rubbing in utero. In children with a moderate form of DEB with no or moderate skin fragility, a glycine substitution near the THD interruption domain of the collagen VII leading to thermolabile protein could explain this phenomenon. (Source: British Journal of Dermatology)

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Apr 14, 2014 04:00PM

Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies

ConclusionsThis is the first prospective American study to document the incidence of IHs in infants followed from birth to early infancy. The association with placental anomalies was statistically significant. The overall incidence mirrors prior estimates, but the need for treatment was lower than previously reported. (Source: British Journal of Dermatology)

Apr 14, 2014 04:00PM

The effect of tacrolimus compared with betamethasone valerate on the skin barrier in volunteers with quiescent atopic dermatitis

ConclusionIn quiescent AD, 4 weeks of BMVc treatment adversely affected the biophysical properties of the skin and reduced the levels of natural moisturizing factor, whereas TACo improved the condition of the skin barrier. (Source: British Journal of Dermatology)