Dr. William Ting, Board-Certified Dermatologist
at California Dermatology Care
2262 Camino Ramon, San Ramon, CA 94583
500 Alfred Nobel Drive, Suite #185, Hercules, CA 94547
Tel: 925-328-0255
Email: staff@CalDermCare.com


Advanced Care with a Personal Touch

   

 

 

Medical Dermatology    Evidence-based medicine   Customized solution   Personal care

Latest Dermatology Headlines

Dr. William Ting has expertise in treating the entire spectrum of medical dermatology, with emphasis in preventive medicine and personalized recommendations. He enjoys taking care of patients with acne, eczema, hair and nail disorders, rashes, psoriasis and skin cancers.

He is at the forefront of medical dermatology and dermatologic research. He continues to publish articles in peer-reviewed dermatology journals. He is an early pioneer of photodynamic therapy (PDT) and one of the most experienced practitioners of PDT in the Bay Area. He is the first dermatologist in the San Francisco Bay Area and Northern California to introduce Lutronic Spectra, GenesisPlus, Picosure Lasers for melasma, acne, scar revision, pore size reduction as well as the Cutera GenesisPlus laser for advanced nail fungus laser treatment, keloid and hypertrophic scar, warts and scar revision.

Dr. Ting is a fellow of the American Academy of Dermatology (AAD) and American Society of Dermatologic Surgery (ASDS). He is a member of the National Psoriasis Foundation and International Hyperhidrosis Society.

Innovative Therapeutic Approach to Common Skin Conditions

Acne

Eczema (Atopic Dermatitis)

Hair and Nail disorders

  • Maximize therapeutic synergy and efficacy by utilizing both prescription-strength and over-the counter products when available
  • Comprehensive workup including bloodwork and biopsy if necessary
  • Systemic oral hormonal therapy for women and men when indicated

Psoriasis 

Rosacea

  • Multi-prong approach to minimize redness
  • Low-dose 'non-antibiotic' anti-inflammatory oral medication for long-term remission 
  • Emphasis on prevention
  • Fotofacial/IPL laser utilizing Cynosure XPL/Elite MPX
  • Cutera GenesisPlus Laser with or without combination with IPL 
  • Diode laser for facial veins
  • VBeam Pulse Dye Laser, the new gold standard for rosacea and facial redness

Skin Cancer 

  • Emphasis on prophylactic treatments with topical 5-FU, imiquimod, diclofenac, ingenol mebutate and oral chemopreventive therapy such as Erivedge, and Soriatane.
  • Reduce future risks of skin cancer with photodynamic therapy, TCA chemical peels and/or fractional CO2 resurfacing laser  
  • Superficial Radiotherapy (SRT) may be the new gold standard as a nonsurgical modality to treat non-melanoma skincancer
  • Mohs Surgery to achieve highest cure rate and tissue sparing
  • Close colloboration with plastic surgeon(s) as needed  

Sweating Disorder (Hyperhidrosis) 

Vitiligo

Warts 


ABCD of Mole Check

 

 

Common Medical Dermatology Diagnostics and Therapeutics:

Dermatology Links:

American Academy of Dermatology
American Society of Dermatologic Surgery
American Society of Mohs Surgery
International Hyperhidrosis Society
National Psoriasis Foundation

 Latest Dermatology Headlines:

Latest Dermatology Headlines
Sat, 13 Feb 2016 03:09:44 +0100

http://www.medworm.com/rss/index.php/Dermatology/12/

Feb 12, 2016 07:09PM

Use of Low-Cost Videomicroscopy versus Standard Videodermatoscopy in Trichoscopy: A Controlled, Blinded Noninferiority Trial

In conclusion, our study suggests that the potential accuracy of low-cost VMs in the evaluation of hair loss may have some pitfalls. Therefore, a low-cost VM should not be routinely used for reliable scalp trichoscopy, unless supported by individual controlled noninferiority trials.Skin Appendage Disord 2015;1:172-174 (Source: Skin Appendage Disorders)

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Feb 12, 2016 07:09PM

Actinic Granuloma with Focal Segmental Glomerulosclerosis

We report a case of a 52-year-old woman who presented with asymptomatic annular erythematous plaques on the forehead and both cheeks persisting for 2 years. The clinical presentation and histopathologic findings support the diagnosis of actinic granuloma. During that period of time, she also developed focal segmental glomerulosclerosis. The association between actinic granuloma and focal segmental glomerulosclerosis needs to be clarified by further studies.Case Rep Dermatol 2016;8:36-41 (Source: Case Reports in Dermatology)

Feb 12, 2016 07:09PM

Acquired Localized Cutis Laxa due to Increased Elastin Turnover

In conclusion, we report a case of acquired localized cutis laxa with a lack of elastic fibers in the skin of the patient's upper body. The lack of elastic fibers in the affected skin was combined with increased mRNA expression and protein levels of elastin. These findings indicate that elastin synthesis was increased but did not lead to deposited elastic fibers in the tissue.Case Rep Dermatol 2016;8:42-51 (Source: Case Reports in Dermatology)

Feb 12, 2016 07:08PM

Hyperkeratosis in human lower limb lymphedema: the effect of stagnant tissue fluid/lymph

ConclusionHyperkeratosis in lymphedema may be the effect of a high concentration of cytokines in the stagnant TF/L tissue, but not because of presumed changes in the KC. (Source: Journal of the European Academy of Dermatology and Venereology)

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Feb 12, 2016 07:08PM

The FDA Pivots Toward Patient-Centeredness: Patient Engagement Advisory Committee

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Ankle Brachial Index and Foot Ulcer Etiology

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

From the editor?s desk

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Clinical trial news

No abstract available (Source: Advances in Skin and Wound Care)

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Feb 12, 2016 07:08PM

Industry news

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Association news

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Pieces of the HOPD Payment Puzzle: NCCI Edits, OPPS Payment Status Indicators, and LCDs

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Negative-Pressure Therapy to Reduce the Risk of Wound Infection Following Diverting Loop Ileostomy Reversal: An Initial Study

CONCLUSIONS: The negative-pressure Prevena System was safe and easy to use and may prevent SSIs in dirty wounds, such as those from ileostomy closure. (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Tissue-Engineered Skin Substitute Enhances Wound Healing after Radiation Therapy

CONCLUSIONS: These results indicate that BTESS is the preferred treatment for irradiated wound ulcers. (Source: Advances in Skin and Wound Care)

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Feb 12, 2016 07:08PM

Assessment of Chicken-Egg Membrane as a Dressing for Wound Healing

CONCLUSION: Chicken-egg membrane dressing significantly improves healing of cutaneous wounds in the early stages of wound healing. (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Development of a Nutrition Screening Tool for an Outpatient Wound Center

CONCLUSIONS: Although further studies of validity and reliability are necessary to establish the tool before widespread use, the MEAL Scale is a needed step toward nutrition screening in a wound patient population. (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

The Strategic View of Modified Stage 2 Meaningful Use: Part 3

No abstract available (Source: Advances in Skin and Wound Care)

Feb 12, 2016 07:08PM

Development of a Nutrition Screening Tool for an Outpatient Wound Center

No abstract available (Source: Advances in Skin and Wound Care)

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Feb 12, 2016 07:08PM

Three Cases of Intravascular Large B-Cell Lymphoma Detected in a Biopsy of Skin Lesions

Intravascular large B-cell lymphoma (IVL) is a rare subtype of extranodal malignant lymphoma. The proliferation of neoplastic B cells within small blood vessels causes eruptions and other symptoms in a variety of organs. The random skin biopsy is useful for diagnosing this condition in its early stages. In order to assess the diagnostic utility of this method, we examined 3 cases with the aim of comparing the occurrence of tumor cells in lesional and healthy-looking skin by performing a random skin biopsy of 32 separate sites. Our findings from the total of 32 biopsy specimens collected from the 3 cases indicated that 16 of the 17 sites on the lesional skin and 1 of the 15 sites on the healthy-looking skin were positive for neoplastic cells. This finding suggested that IVL cells occurred m...

Feb 12, 2016 07:08PM

Facial Scars following Toxic Epidermal Necrolysis: Role of Adnexal Involvement

In this report, we present particular facial cutaneous sequelae with histological analysis after TEN. Two young patients who had survived TEN presented permanent multiple hypopigmented papules on the face affecting their quality of life. Histological analysis revealed areas of scarring, dystrophic microcalcifications and sebaceous hyperplasia. Late cutaneous sequelae are well documented; however, the physiopathological mechanisms leading to different clinical presentations remain unknown. We suggest that the destruction of the hair follicle by necrolysis leads to secondary dermal microcalcifications, scarring and sebaceous hyperplasia. Further studies are needed for a better understanding of these findings.Dermatology (Source: Dermatology)

Feb 12, 2016 07:07PM

Polypoid and fungating form of elephantiasic pretibial myxedema with involvement of the hands

(Source: International Journal of Dermatology)

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Feb 12, 2016 05:08PM

Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III?IVB tongue cancer

Conclusions PBT-IACT for stage III?IVB tongue cancer has an acceptable toxicity profile and showed good treatment results. This protocol should be considered as a treatment option for locally advanced tongue cancer. (Source: Journal of Cancer Research and Clinical Oncology)

Feb 12, 2016 04:00PM

John Davies D.Sc.

Publication date: Available online 11 February 2016 Source:Burns Author(s): Peter Shakespeare (Source: Burns)

Feb 12, 2016 01:57PM

CMS clarifies how to report Medicare overpayments

There is finally some clarity about how to report and return Medicare overpayments, under a final rule released by the Centers for Medicare & Medicaid Services Feb. 11. The final regulation clarifies... (Source: Skin and Allergy News)

Feb 12, 2016 08:16AM

CMS extends deadline for 2015 EHR attestation

Physicians and hospitals will have an extra 2 weeks to attest to meaningful use of electronic health records in 2015. (Source: Skin and Allergy News)

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Feb 12, 2016 03:35AM

Distribution of Malassezia species in Mexican seborrheic dermatitis patients

Yeasts of the Malassezia genus are linked to seborrheic dermatitis (SD) in humans; however, etiological species causing this disease can vary according to their geographical location. M. globosa and M. restricta are the most often isolated microorganisms and can be found in the skin of patients with SD. Nevertheless, species identification by molecular methods and the relationship among etio... (Source: African Journal of Microbiology Research)

Feb 12, 2016 01:50AM

An analysis of the teaching of intravenous self?administration in patients with hereditary angio?oedema

ConclusionC1 inhibitor self?administration for the treatment of HAE allows patients to quickly treat attacks at home, potentially reducing attack severity. The results also demonstrate the benefit of self?administered routine prevention therapy in a real?world patient population. Self?administered therapy potentially allows patients to gain greater control over their attacks, resulting in a reduction in healthcare utilization. (Source: Clinical And Experimental Dermatology)

Feb 12, 2016 12:45AM

Panorama Dermatologische Praxis.

Authors: PMID: 26861128 [PubMed - as supplied by publisher] (Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete)

Feb 12, 2016 12:45AM

[Localized, irregular pigmentation of the maxillary gingiva].

Authors: Rahimi-Nedjat RK, Sagheb K, Tuettenberg A, Renné C, Walter C PMID: 26861127 [PubMed - as supplied by publisher] (Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete)

Feb 11, 2016 09:46PM

Alopecia due to an allergic reaction to metal head-pins used in a neurosurgical operation.

CONCLUSION: The history of metal allergy should have been carefully elicited because head fixation with head-pins is essential for neurosurgical procedures. PMID: 26862455 [PubMed] (Source: Surgical Neurology International)

Feb 11, 2016 07:21PM

Increased expression of dermatopontin and its implications for testicular dysfunction in mice.

In conclusion, the present study provided evidence to suggest that DPT may be indicative of mouse testicular dysfunction, since increased expression may be associated with damage to the BTB. PMID: 26861869 [PubMed - as supplied by publisher] (Source: Molecular Medicine Reports)

Feb 11, 2016 04:00PM

[This Week in Science] Bringing atopic dermatitis up to scratch

Author: Angela Colmone (Source: ScienceNOW)

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Feb 11, 2016 04:00PM

[Report] The phenotypic legacy of admixture between modern humans and Neandertals

Many modern human genomes retain DNA inherited from interbreeding with archaic hominins, such as Neandertals, yet the influence of this admixture on human traits is largely unknown. We analyzed the contribution of common Neandertal variants to over 1000 electronic health record (EHR)?derived phenotypes in ~28,000 adults of European ancestry. We discovered and replicated associations of Neandertal alleles with neurological, psychiatric, immunological, and dermatological phenotypes. Neandertal alleles together explained a significant fraction of the variation in risk for depression and skin lesions resulting from sun exposure (actinic keratosis), and individual Neandertal alleles were significantly associated with specific human phenotypes, including hypercoagulation and tobacco use. Our r...

Feb 11, 2016 04:00PM

[Allergy] Bringing atopic dermatitis up to scratch

Targeted therapies are transforming medicine, but complex diseases such as atopic dermatitis are difficult to target. Now, Jarrett et al. report a mechanism that links two contributors ? [Read More] (Source: This Week in Science)

Feb 11, 2016 04:00PM

Table of Contents

(Source: Clinical And Experimental Dermatology)

Feb 11, 2016 04:00PM

An overview of burning mouth syndrome for the dermatologist

This article summarizes the important aspects of the condition, including theories of pathogenesis, diagnosis and management. (Source: Clinical And Experimental Dermatology)

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Feb 11, 2016 04:00PM

Bacterial agents in 248 ticks removed from people from 2002 to 2013

Publication date: Available online 6 February 2016 Source:Ticks and Tick-borne Diseases Author(s): Camille Aubry, Cristina Socolovschi, Didier Raoult, Philippe Parola A retrospective study was conducted to analyze the tick species removed from people and to detect tick-infecting bacteria in the specimens collected over the past 10 years at the reference center for rickettsioses, Marseille, France. A total of 248 ticks were removed from 200 people, including Dermacentor (73), Rhipicephalus (67), Ixodes (60), Amblyomma (8), Argas (3), Hyalomma (1), and Haemaphysalis (1) species. Bacterial DNA was detected in 101 ticks: Rickettsia slovaca (34%) and Rickettsia raoultii (23%) were detected in Dermacentor ticks; Rickettsia conorii (16%) and Rickettsia massiliae (18%) were found in Rhipicep...

Feb 11, 2016 04:00PM

De Novo Mutation in ABCC9 Causes Hypertrichosis Acromegaloid Facial Features Disorder

Abstract A 13?year?old Egyptian girl with generalized hypertrichosis, gingival hyperplasia, coarse facial appearance, no cardiovascular or skeletal anomalies, keloid formation, and multiple labial frenula was referred to our clinic for counseling. Molecular analysis of the ABCC9 gene showed a de novo missense mutation located in exon 27, which has been described previously with Cantu syndrome. An overlap between Cantu syndrome, acromegaloid facial syndrome, and hypertrichosis acromegaloid facial features disorder is apparent at the phenotypic and molecular levels. The patient reported here gives further evidence that these syndromes are an expression of the ABCC9?related disorders, ranging from hypertrichosis and acromegaloid facies to the severe end of Cantu syndrome. (Source: Pedia...

Feb 11, 2016 04:00PM

Treatment of Moderate to Severe Pediatric Psoriasis: A Retrospective Case Series

ConclusionAlthough sample size and study design limit the data from this study, the study provides some guidance where little exists and helps to support the use of these treatments in this setting. (Source: Pediatric Dermatology)

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Feb 11, 2016 04:00PM

Case of metachronous and multifocal extramammary Paget's disease

(Source: The Journal of Dermatology)

Feb 11, 2016 04:00PM

Increase of interleukin?10?producing B cells associated with long?term remission after i.v. immunoglobulin treatment for pemphigus

We present a refractory case of pemphigus vulgaris that achieved long?term remission after i.v. immunoglobulin treatment (IVIG). We evaluated the fluctuation of circulating interleukin?10?producing B cells (B10 cells) during the course in our case and other three patients with pemphigus treated with IVIG without clinical remission. B10 cells were observed predominantly in CD1d?, CD5?, CD9? and CD27+ populations among CD19+ cells in healthy controls, as well as in patients with pemphigus. The frequency of B10 cells among CD19+ cells increased in our case, but not in the other three patients without clinical remission, which leads to speculation on the association between the increase of B10 cells and the achievement of long?term remission after IVIG treatment. (Source: The Jou...

Feb 11, 2016 04:00PM

Unilateral prurigo pigmentosa: A report of two cases

(Source: The Journal of Dermatology)

Feb 11, 2016 04:00PM

Founding an undergraduate society: a student?led initiative to improve dermatology education

This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

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Feb 11, 2016 04:00PM

Development of core outcome sets in hidradenitis suppurativa:a systematic review of outcome measure instruments to inform the process

ConclusionsMultiple, usually unvalidated outcome measure instruments have been used in HS RCTs. Where validation evidence is available there are issues of low methodological quality or incomplete validity assessment and so no instruments can be fully recommended currently.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Is early detection of basal cell carcinoma worthwhile? Systematic review based on the WHO criteria for screening

ConclusionsThe available data point to a slow increase in size of BCC over time. This size is one of the major determinants in the choice of an effective treatment and the associated cost especially for facial BCC. Therefore we conclude that current data support early detection and adequate management of BCCs on the face.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Infiltration of M2?polarized macrophages in infected lymphatic malformations: possible role in disease progression

ConclusionsM2?polarized macrophages that may be recruited through TLOs in infected LMs may contribute to the progression of the disease by secreting VEGF?C, and therefore accelerating the proliferation of lymphatic endothelial cells.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Epidemiology of chronic spontaneous urticaria: results from a nationwide, population?based study in Italy

ConclusionsOur findings on CSU prevalence are consistent with those obtained in previous studies. Furthermore, this large population?based study provides important information regarding the association of CSU with demographic and clinical determinants, which have been examined in the primary care setting.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Editor's Choice

(Source: British Journal of Dermatology)

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Feb 11, 2016 04:00PM

Time for a patient?oriented outcome in vitiligo: the vitiligo noticeability scale

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Rare inherited skin diseases and the Genomics England 100 000 Genome Project

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

A biosimilarity index for psoriasis

Linked Article: Blauvelt, et al. Br J Dermatol 2016; 174: 282?286. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Treating actinic keratosis

Linked Article: Sinnya, et al. Br J Dermatol 2016; 174: 305?311. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Prediction of high total naevus count to estimate melanoma risk. We need more, don't we?

Linked Article: Ribero, et al. Br J Dermatol 2016; 174: 312?318. (Source: British Journal of Dermatology)

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Feb 11, 2016 04:00PM

CARD14 alterations and psoriasis: are psoriasis and related disorders genetic autoinflammatory diseases?

Linked Article: Ammar, et al. Br J Dermatol 2016; 174: 330?337. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

A possible mechanism of hypercoagulation status in scleroderma

Linked Article: Saigusa, et al. Br J Dermatol 2016; 174: 338?347. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Hand dermatitis in construction workers: a lesson in genetic epidemiology

Linked Article: Timmerman, et al. Br J Dermatol 2016; 174: 348?355. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Labelling: do we have it right?

Linked Article: Hauksson, et al. Br J Dermatol 2016; 174: 371?379. (Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Kidney disease in moderate?to?severe psoriasis: a critical appraisal

ConclusionsModerate?to?severe psoriasis is associated with an increased risk of moderate?to?advanced CKD, independently of traditional risk factors. (Source: British Journal of Dermatology)

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Feb 11, 2016 04:00PM

Response to ?Kidney disease in moderate?to?severe psoriasis: a critical appraisal?

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Kidney disease in moderate?to?severe psoriasis: commentary

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Cover Image: Music box spines

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

News and Notices

(Source: British Journal of Dermatology)

Feb 11, 2016 04:00PM

Plain language summaries

Linked Article: Diepgen et al. Br J Dermatol 2016; 174: 319?329. Linked Article: Nemoto et al. Br J Dermatol 2016; 174: 296?304. Linked Article: Batchelor et al. Br J Dermatol 2016; 174: 386?394. Linked Article: Timmerman et al. Br J Dermatol 2016; 174: 348?355. Linked Article: Venturini et al. Br J Dermatol 2016; 174: 380?385. Linked Article: Lee et al. Br J Dermatol 2016; 174: 356?363. Linked Article: Tschandl et al. Br J Dermatol 2016; 174: 364?370. (Source: British Journal of Dermatology)

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Feb 11, 2016 04:00PM

Trachyonychia as the presenting sign of myeloma?associated amyloidosis

(Source: International Journal of Dermatology)

Feb 11, 2016 04:00PM

Langerhans cell histiocytosis in an adult patient presenting with eruptions on the scalp and trunk accompanied by lytic lesions on the skull

(Source: International Journal of Dermatology)

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Feb 11, 2016 04:00PM

The effects of narrowbands of visible light upon some skin disorders: a review

Abstract This review article focuses on clinical studies published in the fields of (i) photorejuvenation and anti?ageing, (ii) oily or acne?prone skin and related imperfections, (iii) skin pigmentation and lightening, (iv) dandruff and other Malassezia?related skin disorders and (v) prevention and reversal of hair loss using non?thermal, non?ablative devices (principally light?emitting diodes). It mainly focuses on clinical proof of performance and also on in vitro studies that support the clinical findings. The mode of action of narrowbands of visible light upon the skin is only briefly discussed since their biological effects have been previously reviewed. Résumé Cet article établit une revue des études cliniques publiées dans les domaines (i) du photorajeunissement et...

Feb 11, 2016 04:00PM

Modulation of ROS levels in fibroblasts by altering mitochondria regulates the process of wound healing

Abstract Mitochondria are the major source of reactive oxygen species (ROS) in fibroblasts which are thought to be crucial regulators of wound healing with a potential to affect the expression of nuclear genes involved in this process. ROS generated by mitochondria are involved in all stages of tissue repair process but the regulation of ROS-generating system in fibroblasts still remains poorly understood. The purpose of this study was to better understand molecular mechanisms of how the regulation of ROS levels generated by mitochondria may influence the process of wound repair. Cybrid model system of mtDNA variations was used to study the functional consequences of altered ROS levels on wound healing responses in a uniform nuclear background of cultured ?0 fibroblasts. Mitochon...

Feb 11, 2016 04:00PM

Cutaneous Lupus Erythematosus: An Update on Pathogenesis, Diagnosis and Treatment

Abstract Cutaneous lupus erythematosus (CLE) includes a broad range of dermatologic manifestations, which may or may not be associated with systemic disease. Recent studies in this area continue to shape our understanding of this disease and treatment options. Epidemiologic studies have found an incidence of CLE of 4.30 per 100,000, which approaches similar analysis for systemic lupus erythematosus (SLE). Although there have been extensive efforts to define SLE, the classification of CLE and its subgroups remains a challenge. Currently, diagnosis relies on clinical and laboratory findings as well as skin histology. The Cutaneous Lupus Area and Severity Index? (CLASI?) is a validated measure of disease activity and damage. CLE pathogenesis is multifactorial and includes genetic...

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Feb 11, 2016 04:00PM

Ultraviolet B Phototherapy for Psoriasis: Review of Practical Guidelines

Abstract Psoriasis is an inflammatory skin condition that affects approximately 2 % of people worldwide. Topical treatments, systemic treatments, biologic agents, and phototherapy are all treatment options for psoriasis. Ultraviolet (UV) B phototherapy is most appropriate for patients with >10 % affected body surface area who have not responded to topical treatments. This review outlines the use, dosage, safety, and efficacy of narrowband UVB (NB-UVB) and targeted phototherapy. NB-UVB and excimer laser are effective treatment options for psoriasis; they are administered two to three times weekly until clearance followed by maintenance treatment before discontinuation. Long-term data on NB-UVB indicate that it has a good safety profile. NB-UVB is commonly used with adjunctive...

Feb 11, 2016 12:27PM

Dermatologic features may help distinguish Zika infection

Dermatologists may be seeing patients who have recently traveled to an area affected by the current Zika outbreaks, who present with a rash and possibly a fever. (Source: Skin and Allergy News)

Feb 11, 2016 09:00AM

Neanderthal DNA has subtle but significant impact on human traits

The first study comparing Neanderthal DNA from the genomes of adults of European ancestry and their medical records has revealed its effect on modern human biology. Reporting in Science, investigators with Vanderbilt University funded by NHGRI's Electronic Medical Records and Genomics (eMERGE) program found associations between Neanderthal DNA and immunological, dermatological, neurological, psychiatric and reproductive diseases. (Source: NHGRI Homepage Highlights)

Feb 11, 2016 06:52AM

Borrelia mayonii is new cause of Lyme disease variant

A new species of Borrelia has been linked to a variant of Lyme disease with symptoms that differ somewhat from typical Lyme borreliosis. Of 100,545 routine clinical specimens tested at the Mayo Clinic in Rochester, Minn., for Lyme borreliosis between 2003 and 2014, six clinical specimens ?... (Source: Skin and Allergy News)

Feb 11, 2016 06:09AM

Erratum

Skin Appendage Disord 2015;1:168 (Source: Skin Appendage Disorders)

Feb 11, 2016 06:09AM

Disseminated nodules after vaccines for hyposensitization for mites. Pseudolymphoma or lymphoma?

(Source: Journal of the European Academy of Dermatology and Venereology)

Feb 11, 2016 06:08AM

Facial Scars following Toxic Epidermal Necrolysis: Role of Adnexal Involvement?

In this report, we present particular facial cutaneous sequelae with histological analysis after TEN. Two young patients who had survived TEN presented permanent multiple hypopigmented papules on the face affecting their quality of life. Histological analysis revealed areas of scarring, dystrophic microcalcifications and sebaceous hyperplasia. Late cutaneous sequelae are well documented; however, the physiopathological mechanisms leading to different clinical presentations remain unknown. We suggest that the destruction of the hair follicle by necrolysis leads to secondary dermal microcalcifications, scarring and sebaceous hyperplasia. Further studies are needed for a better understanding of these findings.Dermatology (Source: Dermatology)

Feb 11, 2016 06:08AM

False-Negative Cases on Confocal Microscopy Examination: A Retrospective Evaluation and Critical Reappraisal

Conclusion: Confocal and dermoscopic examination, along with patient-related information and clinical history, can lead to an optimal patient management.Dermatology (Source: Dermatology)

Feb 10, 2016 11:00PM

Skin Infections Common in High School Wrestlers, Study Finds

Title: Skin Infections Common in High School Wrestlers, Study FindsCategory: Health NewsCreated: 2/10/2016 12:00:00 AMLast Editorial Review: 2/11/2016 12:00:00 AM (Source: MedicineNet Skin General)

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Feb 10, 2016 04:00PM

Infantile Hemangiomas in Twins: A Prospective Cohort Study

ConclusionsThese findings suggest that the origin of IHs is multifactorial and that predisposing factors such as birthweight, sex, and GA may interact with one another such that a threshold is reached for clinical expression. (Source: Pediatric Dermatology)

Feb 10, 2016 04:00PM

Unique coexistence of cold and solar urticaria and its efficient treatment

(Source: British Journal of Dermatology)

Feb 10, 2016 04:00PM

Kaposi sarcoma secondary to endogenous adrenocorticotropic hormone?dependent Cushing syndrome

We report a case of KS secondary to endogenous Cushing syndrome (ECS) due to a pituitary adenoma, an association that has been reported only once. We also conducted a search through the Medline and PubMed databases for cases involving KS and ECS, finding only three additional cases that shared common clinical and prognostic features with ours. ECS might favour the development of KS due to immunosuppression. Dermatologists and other clinicians should be aware of this association, as it might be an underdiagnosed condition. It also has an important impact on the management of KS, and based on this review it relies on a good prognosis when ECS is well controlled. (Source: British Journal of Dermatology)

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Feb 10, 2016 04:00PM

Immunobullous disease and ulcerative colitis ? the need of an accurate diagnosis

(Source: British Journal of Dermatology)

Feb 10, 2016 04:00PM

A patient with acantholytic pustular purpuric eruption due to gefitinib successfully treated with systemic antibiotics

Publication date: Available online 9 February 2016 Source:Dermatologica Sinica Author(s): Kai-Lung Chen, Yung-Tsu Cho, Che-Wen Yang, Yi-Shuan Sheen, Jau-Yu Liau, Chia-Yu Chu (Source: Dermatologica Sinica)

Feb 10, 2016 04:00PM

Endurance Exercise Improves Molecular Pathways of Aerobic Metabolism in Patients with Myositis

Conclusion Our data indicate that endurance exercise in patients with established PM and DM may activate an aerobic phenotype, promote muscle growth, and simultaneously suppress the inflammatory response in these patients' muscles as supported by a combination of data on gene expression, proteomics and capillary density in repeated muscle biopsies. This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)

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Feb 10, 2016 04:00PM

Health-related quality-of-life improvements during 98 weeks of infliximab therapy in patients with plaque-type psoriasis in real-world practice

Conclusions Patients with plaque-type psoriasis who received treatment with IFX for 50 weeks or up to 98 weeks reported substantial HRQoL improvement. (Source: Quality of Life Research)

Feb 10, 2016 04:00PM

Carbon dioxide laser ablation of dermatosis papulosa nigra: high satisfaction and few complications in patients with pigmented skin

We report the largest case series to date of patients with DPN ablated with the carbon dioxide (CO2) laser. A retrospective case note review was conducted of all patients with DPN treated in our laser clinic in the last five years, and a post-treatment telephone survey was undertaken to assess patient satisfaction. Forty-five patients were identified, with a median age of 41 years (range 25?74 years), of whom 37 (82 %) were female. The median number of treatments undertaken was three (range 1?10). Of the 18 respondents to the telephone survey, when asked to grade their satisfaction with the procedure out of 10, median response was 9.5 (range 6?10) with nine patients citing the maximum score of 10. All patients replied that their confidence had improved following the procedure and ...

Feb 10, 2016 04:00PM

Babesiosis in dogs

WE read with interest the news that the RSPCA was shocked at the number of dogs being imported from countries in Eastern Europe among others (VR, January30, 2016, vol 178, p 106). We would like to report what we believe is the first outbreak of babesiosis in Harlow, Essex. Three dogs from separate households have, within the past three months, contracted babesiosis without travelling abroad. A common link between the three is that they are all regularly exercised in an uncultivated park area of land within the town. We have recovered what we believe to be Dermacentor species ticks from two dogs. There has been a marked increase in the number of dogs being rescued from abroad into the area but we are at a loss to know why the requirement to treat dogs for ticks upon entry to the UK was rela...

Feb 10, 2016 04:00PM

Secukinumab improves patient?reported psoriasis symptoms of itching, pain, and scaling: results of two phase 3, randomized, placebo?controlled clinical trials

ConclusionSecukinumab significantly improves patient?reported itching, pain, and scaling in adults with moderate to severe psoriasis compared with placebo. (Source: International Journal of Dermatology)

Feb 10, 2016 04:00PM

Cutaneous involvement in multiple myeloma (MM): A case series with clinicopathologic correlation

Disease-specific skin lesions are rare in patients with multiple myeloma (MM). (Source: Journal of the American Academy of Dermatology)

Feb 10, 2016 04:00PM

Resolution of Cutaneous Sarcoidosis Following Topical Application of Ganoderma lucidum (Reishi Mushroom)

Abstract Ganoderma lucidum (reishi mushroom) has been used in traditional Chinese and Japanese medicine as a herbal remedy for over 2000 years. Studies have shown that G. lucidum has anti-allergic, anti-oxidant, anti-tumor, anti-viral, and anti-inflammatory properties. A review of the literature revealed that there were no studies examining the use of G. lucidum for the treatment of skin diseases. Here, we report the case of a 44-year-old male patient who used soap enriched with G. lucidum and goat?s milk for 3 days in treating annular cutaneous sarcoidosis. The patient showed almost complete regression of the lesions. (Source: Dermatology and Therapy)

Feb 10, 2016 02:04PM

[Isolated epidermal cysts of the vulva].

Authors: Kalampalikis A, Scheungraber C, Goetze S, Schliemann S, Elsner P Abstract Vulvar cysts are rare und benign entities. They are epidermoid cysts which may develop following trauma or surgery. They can also spontaneously develop. They vary in number and size. They grow slowly and tend to show calcification. The treatment consists of surgical removal. Other methods are pinch-punch excision, heat application, and incision. PMID: 26857133 [PubMed - as supplied by publisher] (Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete)

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Feb 10, 2016 02:04PM

[Eczematous disorders in adolescents].

Authors: Fölster-Holst R Abstract Eczematous disorders in adolescence (definition WHO: the period between 10 and 20 years) are common and include mainly atopic dermatitis, contact eczema, and seborrheic dermatitis. They all share the similarity of inflammatory reactions which mainly affect the epidermis and can take a chronic course, depending on the underlying dermatosis. In the following article, the particularities of eczematous diseases in adolescents are discussed. PMID: 26857132 [PubMed - as supplied by publisher] (Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete)

Feb 10, 2016 02:04PM

[Overview of dermatological registries in Germany].

Authors: Nast A PMID: 26857131 [PubMed - as supplied by publisher] (Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete)

Feb 10, 2016 12:40PM

The response of tenocytes to commercial scaffolds used for rotator cuff repair.

Authors: Smith RD, Carr A, Dakin SG, Snelling SJ, Yapp C, Hakimi O Abstract Surgical repairs of rotator cuff tears have high re-tear rates and many scaffolds have been developed to augment the repair. Understanding the interaction between patients' cells and scaffolds is important for improving scaffold performance and tendon healing. In this in vitro study, we investigated the response of patient-derived tenocytes to eight different scaffolds. Tested scaffolds included X-Repair, Poly-Tape, LARS Ligament, BioFiber (synthetic scaffolds), BioFiber-CM (biosynthetic scaffold), GraftJacket, Permacol, and Conexa (biological scaffolds). Cell attachment, proliferation, gene expression, and morphology were assessed. After one day, more cells attached to synthetic scaffolds with dense, fine ...

Feb 10, 2016 11:23AM

EXCLUSIVE: Dermatologist reveals hidden sun dangers that might give YOU cancer

AS EXPERTS warn there is no such thing as a ?healthy? tan, a dermatologist discusses how severe the risk of deadly sun damage really is. (Source: Daily Express - Health)